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ChemicalBook >> CAS DataBase List >> Pimavanserin

Pimavanserin

Pimavanserin price.
  • $22 - $1871.1
  • Product name: Pimavanserin
  • CAS: 706779-91-1
  • MF: C25H34FN3O2
  • MW: 427.55
  • EINECS:1806241-263-5
  • MDL Number:
  • Synonyms:Pimavanserin;PIMAVANSERIN/1-(4-FLUOROBENZYL)-3-(4-ISOBUTOXYBENZYL)-1-(1-METHYLPIPERIDIN-4-YL)UREA;Unii-jz963p0dik;Pimavamserin;1-[(4-fluorophenyl)Methyl]-1-(1-Methylpiperidin-4-yl)-3-{[4-(2-Methylpropoxy)phenyl]Methyl}urea;N-(4-Fluorobenzyl)-N-(1-Methylpiperidin-4-yl)-N'-[[4-(2-Methylpropyloxy)phenyl]Methyl]carbaMide;N-[(4-Fluorophenyl)Methyl]-N-(1-Methyl-4-piperidinyl)-N'-[[4-(2-Methylpropoxy)phenyl]Methyl]urea;Urea,N-[(4-fluorophenyl)Methyl]-N-(1-Methyl-4-piperidinyl)-N'-[[4-(2-Methylpropoxy)phenyl]Methyl]-
24 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Chemtos
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 25mg
  • 50mg
  • 250mg
  • 500mg
  • 5mg
  • 10mg
  • 100MG
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product numberJ97003
  • Product descriptionPimavanserin
  • Packaging10mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0393
  • Product descriptionPimavanserin
  • Packaging5mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003848
  • Product descriptionPIMAVANSERIN 95.00%
  • Packaging100MG
  • Price$1871.1
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003848
  • Product descriptionPIMAVANSERIN 95.00%
  • Packaging10MG
  • Price$739.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003848
  • Product descriptionPIMAVANSERIN 95.00%
  • Packaging5MG
  • Price$236.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB8019
  • Product descriptionPimavanserin
  • Packaging5mg
  • Price$58
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB8019
  • Product descriptionPimavanserin
  • Packaging10mM(in 1mL DMSO)
  • Price$61
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB8019
  • Product descriptionPimavanserin
  • Packaging10mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFP27045
  • Product descriptionPimavanserin
  • Packaging25mg
  • Price$62.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFP27045
  • Product descriptionPimavanserin
  • Packaging100mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number23462
  • Product descriptionPimavanserin ≥98%
  • Packaging5mg
  • Price$22
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23462
  • Product descriptionPimavanserin ≥98%
  • Packaging10mg
  • Price$41
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23462
  • Product descriptionPimavanserin ≥98%
  • Packaging25mg
  • Price$86
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23462
  • Product descriptionPimavanserin ≥98%
  • Packaging50mg
  • Price$108
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3378
  • Product descriptionPimavanserin 99.99%
  • Packaging25mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3378
  • Product descriptionPimavanserin 99.99%
  • Packaging50mg
  • Price$80
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J97003 Pimavanserin 10mg $60 2021-12-16 Buy
AK Scientific Y0393 Pimavanserin 5mg $45 2021-12-16 Buy
American Custom Chemicals Corporation API0003848 PIMAVANSERIN 95.00% 100MG $1871.1 2021-12-16 Buy
American Custom Chemicals Corporation API0003848 PIMAVANSERIN 95.00% 10MG $739.2 2021-12-16 Buy
American Custom Chemicals Corporation API0003848 PIMAVANSERIN 95.00% 5MG $236.5 2021-12-16 Buy
ApexBio Technology B8019 Pimavanserin 5mg $58 2021-12-16 Buy
ApexBio Technology B8019 Pimavanserin 10mM(in 1mL DMSO) $61 2021-12-16 Buy
ApexBio Technology B8019 Pimavanserin 10mg $75 2021-12-16 Buy
Biosynth Carbosynth FP27045 Pimavanserin 25mg $62.5 2021-12-16 Buy
Biosynth Carbosynth FP27045 Pimavanserin 100mg $150 2021-12-16 Buy
Cayman Chemical 23462 Pimavanserin ≥98% 5mg $22 2024-03-01 Buy
Cayman Chemical 23462 Pimavanserin ≥98% 10mg $41 2024-03-01 Buy
Cayman Chemical 23462 Pimavanserin ≥98% 25mg $86 2024-03-01 Buy
Cayman Chemical 23462 Pimavanserin ≥98% 50mg $108 2024-03-01 Buy
ChemScene CS-3378 Pimavanserin 99.99% 25mg $50 2021-12-16 Buy
ChemScene CS-3378 Pimavanserin 99.99% 50mg $80 2021-12-16 Buy

Properties

Melting point :100-103oC
Boiling point :604.2±55.0 °C(Predicted)
Density :1.15±0.1 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :Methanol (Slightly)
pka :13.52±0.46(Predicted)
form :Solid
color :Pale Yellow to Pale Orange
InChI :InChI=1S/C25H34FN3O2/c1-19(2)18-31-24-10-6-20(7-11-24)16-27-25(30)29(23-12-14-28(3)15-13-23)17-21-4-8-22(26)9-5-21/h4-11,19,23H,12-18H2,1-3H3,(H,27,30)
InChIKey :RKEWSXXUOLRFBX-UHFFFAOYSA-N
SMILES :N(CC1=CC=C(F)C=C1)(C1CCN(C)CC1)C(NCC1=CC=C(OCC(C)C)C=C1)=O
CAS DataBase Reference :706779-91-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Pimavanserin is a kind of novel oral administrated drug for treatment of Parkinson's psychosis developed by Acadia pharmaceutical Company (US) with the trade name being Pimavanserin. In September 3rd 2014, it has been granted by the US Food and Drug Administration (FDA) for breakthrough therapy certification. Breakthrough therapy certification is created by the FDA for accelerating the development and review of new drugs for treatment of serious or life-threatening diseases.
Currently there are about seven millions to ten million of patients of Parkinson's disease worldwide with China contributing 2.6 million, ranking first in the world with 100,000 new patients emerging every year. More than 50% of patients of Parkinson's disease have had psychiatric symptoms (PDP). These psychiatric symptoms are mainly manifested as hallucinations and delusions, bringing greater challenge to the treatment and care for patients of Parkinson's disease. Dopamine is the primary target for the treatment of Parkinson's disease because most antipsychotics drugs will block the dopamine in the brain of the patients of Parkinson’s disease, making their situation of motor dysfunction be even worse, and thus currently not being suitable for these patients.
structure of Pimavanserin