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ChemicalBook >> CAS DataBase List >> Pazopanib Hydrochloride

Pazopanib Hydrochloride

Pazopanib Hydrochloride price.
  • $25 - $1620
  • Product name: Pazopanib Hydrochloride
  • CAS: 635702-64-6
  • MF: C21H24ClN7O2S
  • MW: 473.98
  • EINECS:619-728-0
  • MDL Number:MFCD12546138
  • Synonyms:Unii-33Y9anm545;BenzenesulfonaMide, 5-[[4-[(2,3-diMethyl-2H-indazol-6-yl)MethylaMino]-2-pyriMidinyl]aMino]-2-Methyl-, hydrochloride;786034;ArMala;Pazopanib Hydrochloride (GW786034);5-(4-((2,3-diMethyl-2H-indazol-6-yl)(Methyl)aMino)pyriMidin-2-ylaMino)-2-MethylbenzenesulfonaMide hydrochloride;Pazopanib HCl (GW786034 HCl);Pazopanib HCI
32 prices
Selected condition：
Brand
  • Abosyn
  • Adipogen Life Sciences
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Atlantic Research Chemicals
  • AvaChem
  • Biosynth Carbosynth
  • Chemcia Scientific
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
Package
  • 20mg
  • 100mg
  • 250mg
  • 500mg
  • 2g
  • 5g
  • 5gm:
  • 10mM(in 1mL DMSO)
  • 1mg
  • 1unit
  • 5MG
  • 10mg
  • 25MG
  • 50mg
  • 1g
  • ManufacturerAbosyn
  • Product number61-11484
  • Product descriptionPazopanibhydrochloride 95-98%
  • Packaging1g
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3748-M010
  • Product descriptionPazopanib.hydrochloride ≥98%(HPLC)
  • Packaging10mg
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1058A-M001
  • Product descriptionPazopanibhydrochloride ≥95%
  • Packaging1mg
  • Price$54
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3748-M050
  • Product descriptionPazopanib.hydrochloride ≥98%(HPLC)
  • Packaging50mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0024414
  • Product descriptionPAZOPANIB HYDROCHLORIDE 95.00%
  • Packaging1MG
  • Price$166.95
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0024414
  • Product descriptionPAZOPANIB HYDROCHLORIDE 95.00%
  • Packaging5MG
  • Price$765.89
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0024414
  • Product descriptionPAZOPANIB HYDROCHLORIDE 95.00%
  • Packaging25MG
  • Price$1119.41
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8347
  • Product descriptionPazopanibHydrochloride
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8347
  • Product descriptionPazopanibHydrochloride
  • Packaging25mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8347
  • Product descriptionPazopanibHydrochloride
  • Packaging10mM(in 1mL DMSO)
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8347
  • Product descriptionPazopanibHydrochloride
  • Packaging100mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8347
  • Product descriptionPazopanibHydrochloride
  • Packaging500mg
  • Price$480
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60423
  • Product descriptionPazopanibHCl(GW786034HCl) ≥98%
  • Packaging20mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerAtlantic Research Chemicals
  • Product numberXS0011866
  • Product descriptionPazopanibhydrochloride 95%
  • Packaging5gm:
  • Price$282.77
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2631S
  • Product descriptionPazopanib Hydrochloride
  • Packaging10mg
  • Price$29
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2631S
  • Product descriptionPazopanib Hydrochloride
  • Packaging25mg
  • Price$39
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Abosyn 61-11484 Pazopanibhydrochloride 95-98% 1g $160 2021-12-16 Buy
Adipogen Life Sciences AG-CR1-3748-M010 Pazopanib.hydrochloride ≥98%(HPLC) 10mg $25 2021-12-16 Buy
Adipogen Life Sciences SYN-1058A-M001 Pazopanibhydrochloride ≥95% 1mg $54 2021-12-16 Buy
Adipogen Life Sciences AG-CR1-3748-M050 Pazopanib.hydrochloride ≥98%(HPLC) 50mg $75 2021-12-16 Buy
American Custom Chemicals Corporation API0024414 PAZOPANIB HYDROCHLORIDE 95.00% 1MG $166.95 2021-12-16 Buy
American Custom Chemicals Corporation API0024414 PAZOPANIB HYDROCHLORIDE 95.00% 5MG $765.89 2021-12-16 Buy
American Custom Chemicals Corporation API0024414 PAZOPANIB HYDROCHLORIDE 95.00% 25MG $1119.41 2021-12-16 Buy
ApexBio Technology A8347 PazopanibHydrochloride 1unit $28 2021-12-16 Buy
ApexBio Technology A8347 PazopanibHydrochloride 25mg $50 2021-12-16 Buy
ApexBio Technology A8347 PazopanibHydrochloride 10mM(in 1mL DMSO) $55 2021-12-16 Buy
ApexBio Technology A8347 PazopanibHydrochloride 100mg $150 2021-12-16 Buy
ApexBio Technology A8347 PazopanibHydrochloride 500mg $480 2021-12-16 Buy
Arctom CFN60423 PazopanibHCl(GW786034HCl) ≥98% 20mg $70 2021-12-16 Buy
Atlantic Research Chemicals XS0011866 Pazopanibhydrochloride 95% 5gm: $282.77 2021-12-16 Buy
AvaChem 2631S Pazopanib Hydrochloride 10mg $29 2021-12-16 Buy
AvaChem 2631S Pazopanib Hydrochloride 25mg $39 2021-12-16 Buy

Properties

Melting point :>290°C (dec.)
storage temp. :Hygroscopic, Refrigerator, under inert atmosphere
solubility :Acetonitrile (Slightly), DMSO (Slightly)
form :Yellow powder.
color :White to Off-White
Stability :Hygroscopic
InChIKey :MQHIQUBXFFAOMK-UHFFFAOYSA-N
SMILES :CC1N(N=C2C=C(N(C3C=CN=C(NC4C=CC(C)=C(S(=O)(=O)N)C=4)N=3)C)C=CC=12)C.Cl

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Pazopanib Hydrochloride is the hydrochloride salt of a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. It is an oral second-generation multitarget TKI developed by GSK and approved for marketing by the FDA in 2009 and the EMA in 2010. It targets the VEGFR, platelet-derived growth factor receptor, and c-kit, key proteins responsible for tumor growth and survival. It is used to treat patients with advanced RCC and advanced soft tissue sarcoma who have experienced chemotherapy. Pazopanib Hydrochloride has a role as an antineoplastic agent, a vascular endothelial growth factor receptor antagonist, a tyrosine kinase inhibitor, and an angiogenesis-modulating agent.

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