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ChemicalBook >> CAS DataBase List >> PF-562271

PF-562271

PF-562271 price.
  • $28 - $2541.5
  • Product name: PF-562271
  • CAS: 939791-38-5
  • MF: C27H26F3N7O6S2
  • MW: 665.66
  • EINECS:-0
  • MDL Number:MFCD14105612
  • Synonyms:PF-562271 PhSO3H salt;PF-562271 benzenesulfonate salt;PF-00562271 (PF-562271);N-[3-[[[2-[(2,3-Dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]-N-methyl-methanesulfonamide benzenesulfonate;PF-562271 (besylate);N-methyl-N-(3-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)pyridin-2-yl)methanesulfonamide benzenesulfonate;PF-00562271, >=98%;PF-562271 benzenesulfonate
23 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 1unit
  • 1mg
  • 5MG
  • 10mg
  • 25mg
  • 10mM(in 1mL DMSO)
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberY0329
  • Product descriptionN-methyl-N-(3-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)pyridin-2-yl)methanesulfonamidebenzenesulfonate
  • Packaging50mg
  • Price$961
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0014065
  • Product descriptionPF-562271 BENZENE SULPHONATE 95.00%
  • Packaging5MG
  • Price$459.8
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8320
  • Product descriptionPF-00562271
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8320
  • Product descriptionPF-00562271
  • Packaging5mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8320
  • Product descriptionPF-00562271
  • Packaging10mM(in 1mL DMSO)
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8320
  • Product descriptionPF-00562271
  • Packaging25mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146153
  • Product descriptionPF-562271 PHSO3H SALT >98%
  • Packaging100mg
  • Price$734.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146153
  • Product descriptionPF-562271 PHSO3H SALT >98%
  • Packaging250mg
  • Price$1356.6
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146153
  • Product descriptionPF-562271 PHSO3H SALT >98%
  • Packaging1g
  • Price$2541.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18499
  • Product descriptionPF-562271 (besylate) ≥98%
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18499
  • Product descriptionPF-562271 (besylate) ≥98%
  • Packaging5mg
  • Price$161
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18499
  • Product descriptionPF-562271 (besylate) ≥98%
  • Packaging10mg
  • Price$266
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18499
  • Product descriptionPF-562271 (besylate) ≥98%
  • Packaging50mg
  • Price$775
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM148801
  • Product descriptionN-methyl-N-(3-(((2-((2-oxoindolin-5-yl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)methyl)pyridin-2-yl)methanesulfonamidebenzenesulfonate 95%+
  • Packaging100mg
  • Price$562
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2663
  • Product descriptionPF-562271besylate 99.17%
  • Packaging5mg
  • Price$144
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2663
  • Product descriptionPF-562271besylate 99.17%
  • Packaging10mg
  • Price$180
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y0329 N-methyl-N-(3-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)pyridin-2-yl)methanesulfonamidebenzenesulfonate 50mg $961 2021-12-16 Buy
American Custom Chemicals Corporation API0014065 PF-562271 BENZENE SULPHONATE 95.00% 5MG $459.8 2021-12-16 Buy
ApexBio Technology A8320 PF-00562271 1unit $28 2021-12-16 Buy
ApexBio Technology A8320 PF-00562271 5mg $70 2021-12-16 Buy
ApexBio Technology A8320 PF-00562271 10mM(in 1mL DMSO) $105 2021-12-16 Buy
ApexBio Technology A8320 PF-00562271 25mg $160 2021-12-16 Buy
Biorbyt Ltd orb146153 PF-562271 PHSO3H SALT >98% 100mg $734.4 2021-12-16 Buy
Biorbyt Ltd orb146153 PF-562271 PHSO3H SALT >98% 250mg $1356.6 2021-12-16 Buy
Biorbyt Ltd orb146153 PF-562271 PHSO3H SALT >98% 1g $2541.5 2021-12-16 Buy
Cayman Chemical 18499 PF-562271 (besylate) ≥98% 1mg $37 2024-03-01 Buy
Cayman Chemical 18499 PF-562271 (besylate) ≥98% 5mg $161 2024-03-01 Buy
Cayman Chemical 18499 PF-562271 (besylate) ≥98% 10mg $266 2024-03-01 Buy
Cayman Chemical 18499 PF-562271 (besylate) ≥98% 50mg $775 2024-03-01 Buy
Chemenu CM148801 N-methyl-N-(3-(((2-((2-oxoindolin-5-yl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)methyl)pyridin-2-yl)methanesulfonamidebenzenesulfonate 95%+ 100mg $562 2021-12-16 Buy
ChemScene CS-2663 PF-562271besylate 99.17% 5mg $144 2021-12-16 Buy
ChemScene CS-2663 PF-562271besylate 99.17% 10mg $180 2021-12-16 Buy

Properties

storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :insoluble in EtOH; insoluble in H2O; ≥11.1 mg/mL in DMSO with gentle warming
form :solid
color :Off-white to light yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P330 Rinse mouth.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.

Description

Focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) are non-receptor tyrosine kinases that constitute the FAK subfamily and play a vital role in many oncogenic pathways. PF-562271 is an ATP-competitive, reversible inhibitor of FAK (IC50 = 1.5 nM) that demonstrates 10-fold reduced potency for PYK2 (IC50 = 14 nM) and >100-fold selectivity against other protein kinases. PF-562271 inhibits FAK phosphorylation with an EC50 value of 93 ng/ml in glioblastoma-bearing mice and has been shown to regress tumors in multiple xenograft models.

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