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ChemicalBook >> CAS DataBase List >> PF-6274484

PF-6274484

PF-6274484 price.
  • $34 - $2200
  • Product name: PF-6274484
  • CAS: 1035638-91-5
  • MF: C18H14ClFN4O2
  • MW: 372.78
  • EINECS:
  • MDL Number:MFCD30182370
  • Synonyms:PF-6274484;N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-2-propenamide;2-Propenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-;PF-6274484 >=98% (HPLC);oxidation,autophosphorylation,PF6274484,PF-6274484,EGFR,signaling,Epidermal growth factor receptor,HER1,protein,ErbB-1,inhibit,kinase,cysteine,Inhibitor;N-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)acrylamide
8 prices
Selected condition：
Brand
  • AK Scientific
  • Cayman Chemical
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 50mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number8711DW
  • Product descriptionN-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]prop-2-enamide
  • Packaging5mg
  • Price$209
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number8711DW
  • Product descriptionN-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]prop-2-enamide
  • Packaging10mg
  • Price$302
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number22698
  • Product descriptionPF-6274484 ≥98%
  • Packaging1mg
  • Price$34
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22698
  • Product descriptionPF-6274484 ≥98%
  • Packaging5mg
  • Price$100
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22698
  • Product descriptionPF-6274484 ≥98%
  • Packaging10mg
  • Price$166
  • Updated2024-03-01
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC11320
  • Product descriptionPF-6274484 >98%
  • Packaging250mg
  • Price$1100
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC11320
  • Product descriptionPF-6274484 >98%
  • Packaging1g
  • Price$2200
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberP294153
  • Product descriptionPF6274484
  • Packaging50mg
  • Price$820
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8711DW N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]prop-2-enamide 5mg $209 2021-12-16 Buy
AK Scientific 8711DW N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]prop-2-enamide 10mg $302 2021-12-16 Buy
Cayman Chemical 22698 PF-6274484 ≥98% 1mg $34 2024-03-01 Buy
Cayman Chemical 22698 PF-6274484 ≥98% 5mg $100 2024-03-01 Buy
Cayman Chemical 22698 PF-6274484 ≥98% 10mg $166 2024-03-01 Buy
DC Chemicals DC11320 PF-6274484 >98% 250mg $1100 2021-12-16 Buy
DC Chemicals DC11320 PF-6274484 >98% 1g $2200 2021-12-16 Buy
TRC P294153 PF6274484 50mg $820 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :DMF: 33 mg/ml; DMSO: 25 mg/ml
form :A crystalline solid
color :Light yellow to orange

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

PF-6274484 is an irreversible EGFR kinase inhibitor that covalently reacts with active-site cysteine residues in the ATP binding pocket. PF-6274484 inhibits autophosphorylation of both wild type and mutant EGFR in tumor cells with IC50 values of 5.8 nM and 6.6 nM, respectively.

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