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ChemicalBook >> CAS DataBase List >> ML-180

ML-180

ML-180 price.
  • $37 - $2000
  • Product name: ML-180
  • CAS: 863588-32-3
  • MF: C20H25ClN4O2
  • MW: 388.89
  • EINECS:
  • MDL Number:MFCD05894342
  • Synonyms:ML-180;SR1848;6-[4-(3-chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1H-pyrimidine-2,4-dione;2,4(1H,3H)-Pyrimidinedione, 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-;6-(4-(3-chlorophenyl)piperazin-1-yl)-3-cyclohexylpyrimidine-2,4(1H,3H)-dione;SR1848 >=98% (HPLC);ML-180 (SR1848);6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexylpyrimidine- ,4(1H,3H)dione
18 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • Cayman Chemical
  • CSNpharm
  • DC Chemicals
Package
  • 002
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 003
  • 1g
  • 001
  • ManufacturerAK Scientific
  • Product numberSYN5289
  • Product descriptionML180
  • Packaging10mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1210813
  • Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1210813
  • Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
  • Packaging10mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1210813
  • Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
  • Packaging50mg
  • Price$189
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1210813
  • Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
  • Packaging100mg
  • Price$339
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1210813
  • Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
  • Packaging250mg
  • Price$633
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1210813
  • Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
  • Packaging1g
  • Price$1629
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15181
  • Product descriptionML-180 ≥98%
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15181
  • Product descriptionML-180 ≥98%
  • Packaging5mg
  • Price$108
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15181
  • Product descriptionML-180 ≥98%
  • Packaging10mg
  • Price$161
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15181
  • Product descriptionML-180 ≥98%
  • Packaging25mg
  • Price$345
  • Updated2024-03-01
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN27223
  • Product descriptionML-180
  • Packaging1mg
  • Price$47
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN27223
  • Product descriptionML-180
  • Packaging5mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN27223
  • Product descriptionML-180
  • Packaging10mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN27223
  • Product descriptionML-180
  • Packaging100mg
  • Price$630
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product number020423
  • Product descriptionML-180(SR1848)
  • Packaging001
  • Price$600
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5289 ML180 10mg $160 2021-12-16 Buy
Ambeed A1210813 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% 5mg $60 2021-12-16 Buy
Ambeed A1210813 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% 10mg $96 2021-12-16 Buy
Ambeed A1210813 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% 50mg $189 2021-12-16 Buy
Ambeed A1210813 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% 100mg $339 2021-12-16 Buy
Ambeed A1210813 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% 250mg $633 2021-12-16 Buy
Ambeed A1210813 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% 1g $1629 2021-12-16 Buy
Cayman Chemical 15181 ML-180 ≥98% 1mg $37 2024-03-01 Buy
Cayman Chemical 15181 ML-180 ≥98% 5mg $108 2024-03-01 Buy
Cayman Chemical 15181 ML-180 ≥98% 10mg $161 2024-03-01 Buy
Cayman Chemical 15181 ML-180 ≥98% 25mg $345 2024-03-01 Buy
CSNpharm CSN27223 ML-180 1mg $47 2021-12-16 Buy
CSNpharm CSN27223 ML-180 5mg $75 2021-12-16 Buy
CSNpharm CSN27223 ML-180 10mg $120 2021-12-16 Buy
CSNpharm CSN27223 ML-180 100mg $630 2021-12-16 Buy
DC Chemicals 020423 ML-180(SR1848) 001 $600 2021-12-16 Buy

Properties

Density :1.312±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 10 mg/ml
form :A crystalline solid
pka :9.37±0.40(Predicted)
color :Off-white to light yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

ML-180 is an inverse agonist of liver receptor homolog-1 (LRH-1, IC50 = 3.7 μM) with maximum efficacy of 64% repression. It is inactive at the related steroidogenic factor-1 transcriptional activator. Through LRH-1, ML-180 alters the expression of haptoglobin and serum amyloid proteins A1 and A4, induces the death of estrogen-receptor negative MDA-MB-231 breast cancer cells, and inhibits the steroidogenic acute regulatory promoter (IC50 = 2.05 μM).

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