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ChemicalBook >> CAS DataBase List >> Hinokitiol

Hinokitiol

Hinokitiol price.
  • $18 - $858.92
  • Product name: Hinokitiol
  • CAS: 499-44-5
  • MF: C10H12O2
  • MW: 164.2
  • EINECS:207-880-7
  • MDL Number:MFCD00040180
  • Synonyms:HINOKITIOL;B-THUJAPLICIN;2-HYDROXY-4-ISOPROPYL-2,4,6-CYCLOHEPTATRIEN-1-ONE;2-hydroxy-6-isopropyl-cyclohepta-2,4,6-trien-1-one;2-hydroxy-6-propan-2-yl-cyclohepta-2,4,6-trien-1-one;2-hydroxy-6-propan-2-ylcyclohepta-2,4,6-trien-1-one;THUJAPLICIN, BETA- (RG);2-Hydroxy-4-isopropylcyclohepta-2,4,6-trien-1-one beta-Thujaplicine
22 prices
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Brand
  • AHH
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Arctom
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • CSNpharm
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 20mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 5G
  • 10g
  • 25g
  • ManufacturerAHH
  • Product numberMT-52558
  • Product descriptionHinokitiol 99%
  • Packaging25g
  • Price$380
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ96280
  • Product descriptionbeta-Thujaplicin
  • Packaging1g
  • Price$27
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA161005
  • Product descriptionHinokitiol 99+%
  • Packaging50mg
  • Price$18
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA161005
  • Product descriptionHinokitiol 99+%
  • Packaging100mg
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA161005
  • Product descriptionHinokitiol 99+%
  • Packaging250mg
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA161005
  • Product descriptionHinokitiol 99+%
  • Packaging1g
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberFFG0000170
  • Product descriptionBETA-THUJAPLICIN 95.00%
  • Packaging5G
  • Price$858.92
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN93995
  • Product descriptionHinokitiol ≥98%
  • Packaging20mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17538
  • Product descriptionHinokitiol ≥98%
  • Packaging25mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17538
  • Product descriptionHinokitiol ≥98%
  • Packaging50mg
  • Price$65
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17538
  • Product descriptionHinokitiol ≥98%
  • Packaging100mg
  • Price$115
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17538
  • Product descriptionHinokitiol ≥98%
  • Packaging250mg
  • Price$231
  • Updated2024-03-01
  • Buy
  • ManufacturerChem-Impex
  • Product number37925
  • Product descriptionHinokitiol,99%(GC) 99%(GC)
  • Packaging1G
  • Price$34.72
  • Updated2021-12-16
  • Buy
  • ManufacturerChem-Impex
  • Product number37925
  • Product descriptionHinokitiol,99%(GC) 99%(GC)
  • Packaging5G
  • Price$106.4
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-7724
  • Product descriptionHinokitiol 99.28%
  • Packaging50mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-7724
  • Product descriptionHinokitiol 99.28%
  • Packaging100mg
  • Price$100
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-52558 Hinokitiol 99% 25g $380 2021-12-16 Buy
AK Scientific J96280 beta-Thujaplicin 1g $27 2021-12-16 Buy
Ambeed A161005 Hinokitiol 99+% 50mg $18 2021-12-16 Buy
Ambeed A161005 Hinokitiol 99+% 100mg $25 2021-12-16 Buy
Ambeed A161005 Hinokitiol 99+% 250mg $25 2021-12-16 Buy
Ambeed A161005 Hinokitiol 99+% 1g $60 2021-12-16 Buy
American Custom Chemicals Corporation FFG0000170 BETA-THUJAPLICIN 95.00% 5G $858.92 2021-12-16 Buy
Arctom CFN93995 Hinokitiol ≥98% 20mg $50 2021-12-16 Buy
Cayman Chemical 17538 Hinokitiol ≥98% 25mg $37 2024-03-01 Buy
Cayman Chemical 17538 Hinokitiol ≥98% 50mg $65 2024-03-01 Buy
Cayman Chemical 17538 Hinokitiol ≥98% 100mg $115 2024-03-01 Buy
Cayman Chemical 17538 Hinokitiol ≥98% 250mg $231 2024-03-01 Buy
Chem-Impex 37925 Hinokitiol,99%(GC) 99%(GC) 1G $34.72 2021-12-16 Buy
Chem-Impex 37925 Hinokitiol,99%(GC) 99%(GC) 5G $106.4 2021-12-16 Buy
ChemScene CS-7724 Hinokitiol 99.28% 50mg $60 2021-12-16 Buy
ChemScene CS-7724 Hinokitiol 99.28% 100mg $100 2021-12-16 Buy

Properties

Melting point :50-52 °C(lit.)
Boiling point :140 °C10 mm Hg(lit.)
Density :1.0041 (rough estimate)
refractive index :1.5190 (estimate)
storage temp. :Sealed in dry,Room Temperature
solubility :Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
form :solid
pka :7.06±0.30(Predicted)
color :White
Odor :at 100.00 %. phenolic woody mossy
Odor Type :woody
Merck :14,9390
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 4 months.
LogP :1.137 (est)
CAS DataBase Reference :499-44-5(CAS DataBase Reference)
NIST Chemistry Reference :2,4,6-Cycloheptatrien-1-one, 2-hydroxy-4-(1-methylethyl)-(499-44-5)
EPA Substance Registry System :2,4,6-Cycloheptatrien-1-one, 2-hydroxy-4-(1-methylethyl)- (499-44-5)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P262 Do not get in eyes, on skin, or on clothing.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P391 Collect spillage. Hazardous to the aquatic environment
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Hinokitol, an iron chelator originally extracted from woods of Thuja plicata and Chamaecyparis obtuse, has been found to inhibit ultraviolet B-induced apoptosis in keratinocytes of murine ear skin via antioxidant activity of metallothionein. Additionally, this compound has been found to also cause apoptotic cell death and cell cycle arrest of proliferating F9 cells via iron deprivation, resulting in an arrest at the G1-S interface or S phase. Antimicrobial activity has also been displayed by Hinokitiol through CPA (carboxypeptidase A) inhibition. Other studies have reported Hinokitiol to inhibit melanin synthesis by reducing protein levels of microphthalmia-associated transcription factor (MITF) and of Tyrosinase, a rate limiting melanogenic enzyme. Hinokitiol is an inhibitor of 12-LO.

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