Betulin
56 prices
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Brand
- Adipogen Life Sciences
- AHH
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Iris Biotech GmbH
- Labseeker
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 10mg
- 20mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- 2g
- 5g
- 10G
- 25g
- 50g
- 100g
- 250g
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0476-G001
- Product descriptionBetulin ≥98%(NMR)
- Packaging1g
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberMT-47881
- Product descriptionBetulinol 98%
- Packaging5g
- Price$280
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberV0184
- Product descriptionBetulin
- Packaging25g
- Price$324
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0001703
- Product descriptionBETULIN 95.00%
- Packaging1G
- Price$653.73
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0001703
- Product descriptionBETULIN 95.00%
- Packaging5G
- Price$970.2
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0001703
- Product descriptionBETULIN 95.00%
- Packaging10G
- Price$1353.66
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN1290
- Product descriptionBetulin
- Packaging20mg
- Price$32
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberSY038977
- Product descriptionBetulin
- Packaging10mg
- Price$16.36
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN98710
- Product descriptionBetulin
- Packaging20mg
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3092
- Product descriptionBetulin
- Packaging25mg
- Price$25
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3092
- Product descriptionBetulin
- Packaging100mg
- Price$35
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3092
- Product descriptionBetulin
- Packaging1g
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3092
- Product descriptionBetulin
- Packaging10g
- Price$345
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546098
- Product descriptionbetulin >98%
- Packaging10mg
- Price$136
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb593790
- Product descriptionBetulin
- Packaging20mg
- Price$187
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546098
- Product descriptionbetulin >98%
- Packaging50mg
- Price$244.8
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Adipogen Life Sciences | AG-CN2-0476-G001 | Betulin ≥98%(NMR) | 1g | $90 | 2021-12-16 | Buy |
AHH | MT-47881 | Betulinol 98% | 5g | $280 | 2021-12-16 | Buy |
AK Scientific | V0184 | Betulin | 25g | $324 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0001703 | BETULIN 95.00% | 1G | $653.73 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0001703 | BETULIN 95.00% | 5G | $970.2 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0001703 | BETULIN 95.00% | 10G | $1353.66 | 2021-12-16 | Buy |
ApexBio Technology | N1290 | Betulin | 20mg | $32 | 2021-12-16 | Buy |
Arctom | SY038977 | Betulin | 10mg | $16.36 | 2021-12-16 | Buy |
Arctom | CFN98710 | Betulin | 20mg | $30 | 2021-12-16 | Buy |
AvaChem | 3092 | Betulin | 25mg | $25 | 2021-12-16 | Buy |
AvaChem | 3092 | Betulin | 100mg | $35 | 2021-12-16 | Buy |
AvaChem | 3092 | Betulin | 1g | $85 | 2021-12-16 | Buy |
AvaChem | 3092 | Betulin | 10g | $345 | 2021-12-16 | Buy |
Biorbyt Ltd | orb546098 | betulin >98% | 10mg | $136 | 2021-12-16 | Buy |
Biorbyt Ltd | orb593790 | Betulin | 20mg | $187 | 2021-12-16 | Buy |
Biorbyt Ltd | orb546098 | betulin >98% | 50mg | $244.8 | 2021-12-16 | Buy |
Properties
Melting point :256-257 °C(lit.)
alpha :D15 +20° (c = 2 in pyridine)
Boiling point :493.26°C (rough estimate)
Density :0.9882 (rough estimate)
refractive index :1.5045 (estimate)
storage temp. :2-8°C
solubility :Chloroform (Slightly), Methanol (Slightly, Heated)
form :Off-white powder
pka :15.10±0.10(Predicted)
color :Pale Brown to Beige
optical activity :+2015 (c 6, pyridine)
Merck :14,1189
Stability :Hygroscopic
InChIKey :FVWJYYTZTCVBKE-ROUWMTJPSA-N
LogP :8.607 (est)
CAS DataBase Reference :473-98-3(CAS DataBase Reference)
NIST Chemistry Reference :Betulin(473-98-3)
alpha :D15 +20° (c = 2 in pyridine)
Boiling point :493.26°C (rough estimate)
Density :0.9882 (rough estimate)
refractive index :1.5045 (estimate)
storage temp. :2-8°C
solubility :Chloroform (Slightly), Methanol (Slightly, Heated)
form :Off-white powder
pka :15.10±0.10(Predicted)
color :Pale Brown to Beige
optical activity :+2015 (c 6, pyridine)
Merck :14,1189
Stability :Hygroscopic
InChIKey :FVWJYYTZTCVBKE-ROUWMTJPSA-N
LogP :8.607 (est)
CAS DataBase Reference :473-98-3(CAS DataBase Reference)
NIST Chemistry Reference :Betulin(473-98-3)
Safety Information
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Signal word: | Warning | ||||||||||||||
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Precautionary statements: |
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Description
Sterol regulatory element binding protein 2 (SREBP-2) regulates cholesterol synthesis by activating the transcription of genes for HMG-CoA reductase and other enzymes of the cholesterol synthetic pathway. When cellular sterol levels are high, SREBP is bound by SCAP and Insig to ER membranes as a glycosylated precursor protein. Upon cholesterol depletion, the protein is cleaved to its active form and translocated into the nucleus to stimulate transcription of genes involved in the uptake and synthesis of cholesterol. Betulin, the precursor of betulinic acid, is a pentacyclic triterpene found in the bark of birch trees. Betulin inhibits the SREBP-driven pathway of cholesterol and fatty acid biosynthesis by promoting SCAP–Insig binding which prevents the activation and release of SREBP-2 from the ER. At 15-30 mg/kg/day, betulin has been shown to decrease lipid levels and increase insulin sensitivity in mice fed a western-type diet. In an atherosclerosis disease model, 30 mg/kg/day betulin can reduce the size and improve the stability of atherosclerotic plaques in LDLR-knockout mice. At 2.5-5 μg/ml betulin, in combination with cholesterol, demonstrates anticancer effects by inducing apoptosis in Jurkat cells, A549 lung carcinoma cells, and HeLa cervical carcinoma cells.More related product prices
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Suppliers and manufacturers
Henan Tianfu Chemical Co.,Ltd.
Hangzhou FandaChem Co.,Ltd.
Nanjing Finetech Chemical Co., Ltd.