GSK-CXCR2
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- $97 - $2230
- Product name: GSK-CXCR2
- CAS: 211096-49-0
- MF: C14H9BrN6O
- MW: 357.16
- EINECS:
- MDL Number:MFCD09971124
- Synonyms:GSK-CXCR2;N-(2-Bromophenyl)-N'-(7-cyano-1H-benzotriazol-4-yl)urea;SB 265610;1-(2-Bromophenyl)-3-(4-cyano-1H-benzo[d] [1,2,3]triazol-7-yl)urea;Urea, N-(2-bromophenyl)-N'-(4-cyano-1H-benzotriazol-7-yl)-;SB265610 >=98% (HPLC);CXCR,nonpeptide,inhibit,Inhibitor,SB-265610,inflammation,recruitment,Delay,SB 265610,healing,neutrophil,SB265610,wound,CXC chemokine receptors
20 prices
Selected condition：
Brand
- AK Scientific
- Alichem
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- Sigma-Aldrich
- Tocris
- TRC
Package
- 10
- 1
- 1mg
- 50
- 5mg
- 10mg
- 25mg
- 1g
- 5g
- ManufacturerAK Scientific
- Product number3699BB
- Product descriptionN-(2-Bromophenyl)-N'-(7-cyano-1H-benzotriazol-4-YL)urea
- Packaging1mg
- Price$206
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3699BB
- Product descriptionN-(2-Bromophenyl)-N'-(7-cyano-1H-benzotriazol-4-YL)urea
- Packaging10mg
- Price$345
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number211096490
- Product description1-(2-Bromophenyl)-3-(4-cyano-1H-benzo[d][1,2,3]triazol-7-yl)urea
- Packaging1g
- Price$929.5
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number211096490
- Product description1-(2-Bromophenyl)-3-(4-cyano-1H-benzo[d][1,2,3]triazol-7-yl)urea
- Packaging5g
- Price$2207.7
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001078
- Product descriptionSB-265610 95.00%
- Packaging1MG
- Price$617.3
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5333
- Product descriptionSB265610
- Packaging10mg
- Price$252
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17879
- Product descriptionSB 265610 ≥98%
- Packaging10mg
- Price$223
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17879
- Product descriptionSB 265610 ≥98%
- Packaging5mg
- Price$130
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17879
- Product descriptionSB 265610 ≥98%
- Packaging1mg
- Price$97
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0004245
- Product descriptionSB-265610 >99.0%
- Packaging10mg
- Price$650
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0004245
- Product descriptionSB-265610 >99.0%
- Packaging25mg
- Price$1150
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11166715
- Product description1-(2-Bromophenyl)-3-(4-cyano-1H-benzo[d][1,2,3]triazol-7-yl)urea 97%
- Packaging1g
- Price$845
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11166715
- Product description1-(2-Bromophenyl)-3-(4-cyano-1H-benzo[d][1,2,3]triazol-7-yl)urea 97%
- Packaging5g
- Price$2230
- Updated2021-12-16
- Buy
- ManufacturerCSNpharm
- Product numberCSN23101
- Product descriptionSB265610
- Packaging25mg
- Price$1070
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML0421
- Product descriptionSB265610 ≥98% (HPLC)
- Packaging5mg
- Price$160
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML0421
- Product descriptionSB265610 ≥98% (HPLC)
- Packaging25mg
- Price$642
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3699BB | N-(2-Bromophenyl)-N'-(7-cyano-1H-benzotriazol-4-YL)urea | 1mg | $206 | 2021-12-16 | Buy |
| AK Scientific | 3699BB | N-(2-Bromophenyl)-N'-(7-cyano-1H-benzotriazol-4-YL)urea | 10mg | $345 | 2021-12-16 | Buy |
| Alichem | 211096490 | 1-(2-Bromophenyl)-3-(4-cyano-1H-benzo[d][1,2,3]triazol-7-yl)urea | 1g | $929.5 | 2021-12-16 | Buy |
| Alichem | 211096490 | 1-(2-Bromophenyl)-3-(4-cyano-1H-benzo[d][1,2,3]triazol-7-yl)urea | 5g | $2207.7 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001078 | SB-265610 95.00% | 1MG | $617.3 | 2021-12-16 | Buy |
| ApexBio Technology | B5333 | SB265610 | 10mg | $252 | 2021-12-16 | Buy |
| Cayman Chemical | 17879 | SB 265610 ≥98% | 10mg | $223 | 2024-03-01 | Buy |
| Cayman Chemical | 17879 | SB 265610 ≥98% | 5mg | $130 | 2024-03-01 | Buy |
| Cayman Chemical | 17879 | SB 265610 ≥98% | 1mg | $97 | 2024-03-01 | Buy |
| ChemScene | CS-0004245 | SB-265610 >99.0% | 10mg | $650 | 2021-12-16 | Buy |
| ChemScene | CS-0004245 | SB-265610 >99.0% | 25mg | $1150 | 2021-12-16 | Buy |
| Crysdot | CD11166715 | 1-(2-Bromophenyl)-3-(4-cyano-1H-benzo[d][1,2,3]triazol-7-yl)urea 97% | 1g | $845 | 2021-12-16 | Buy |
| Crysdot | CD11166715 | 1-(2-Bromophenyl)-3-(4-cyano-1H-benzo[d][1,2,3]triazol-7-yl)urea 97% | 5g | $2230 | 2021-12-16 | Buy |
| CSNpharm | CSN23101 | SB265610 | 25mg | $1070 | 2021-12-16 | Buy |
| Sigma-Aldrich | SML0421 | SB265610 ≥98% (HPLC) | 5mg | $160 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0421 | SB265610 ≥98% (HPLC) | 25mg | $642 | 2024-03-01 | Buy |
Properties
Boiling point :527.0±45.0 °C(Predicted)
Density :1.77±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble15mg/mL, clear
pka :6.13±0.40(Predicted)
form :powder
color :white to light brown
Density :1.77±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble15mg/mL, clear
pka :6.13±0.40(Predicted)
form :powder
color :white to light brown
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | ||||||||||||||
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Description
CXCR2 (IL-8RB) is a seven-transmembrane G protein-coupled receptor whose physiological ligands include IL-8 (CXCL8) and many other CXC chemokines involved in the trafficking and activation of inflammatory cells. It is involved in various inflammatory diseases, including chronic obstructive pulmonary disease, psoriasis, rheumatoid arthritis, and ulcerative colitis. SB 265610 is a nonpeptide, allosteric, inverse agonist of CXCR2 (Kd = 2.51 nM) that prevents receptor activation by binding to a region distinct from the agonist binding site. It does not bind to the related CXCR1 receptor. It has been shown to prevent neutrophil chemotaxis both in vitro and in a rat model of hyperoxia-induced lung injury.More related product prices
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