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ChemicalBook >> CAS DataBase List >> Decernotinib

Decernotinib

Decernotinib price.
  • $36 - $1900
  • Product name: Decernotinib
  • CAS: 944842-54-0
  • MF: C18H19F3N6O
  • MW: 392.38
  • EINECS:-0
  • MDL Number:MFCD27987896
  • Synonyms:Decernotinib;Decernotinib(VX-509);(R)-2-((2-(1H-Pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl)amino)-2-methyl-N-(2,2,2-trifluoroethyl)butanamide;(2R)-2-Methyl-2-[[2-(1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]-N-(2,2,2-trifluoroethyl)butanamide;VRT 831509;VX 509;Butanamide, 2-methyl-2-[[2-(1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]-N-(2,2,2-trifluoroethyl)-, (2R)-;adelatinib
22 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 2mg
  • 5MG
  • 10mg
  • 25mg
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product number4499DP
  • Product descriptionDecernotinib
  • Packaging10mg
  • Price$268
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number4499DP
  • Product descriptionDecernotinib
  • Packaging25mg
  • Price$479
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0024520
  • Product descriptionDECERNOTINIB 95.00%
  • Packaging5MG
  • Price$497.95
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5929
  • Product descriptionDecernotinib(VX-509)
  • Packaging2mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5929
  • Product descriptionDecernotinib(VX-509)
  • Packaging5mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5929
  • Product descriptionDecernotinib(VX-509)
  • Packaging10mM(in 1mL DMSO)
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5929
  • Product descriptionDecernotinib(VX-509)
  • Packaging25mg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19513
  • Product descriptionVX-509 ≥98%
  • Packaging1mg
  • Price$36
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19513
  • Product descriptionVX-509 ≥98%
  • Packaging5mg
  • Price$120
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19513
  • Product descriptionVX-509 ≥98%
  • Packaging10mg
  • Price$172
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19513
  • Product descriptionVX-509 ≥98%
  • Packaging25mg
  • Price$384
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3990
  • Product descriptionDecernotinib 99.45%
  • Packaging2mg
  • Price$72
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3990
  • Product descriptionDecernotinib 99.45%
  • Packaging5mg
  • Price$108
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3990
  • Product descriptionDecernotinib 99.45%
  • Packaging10mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3990
  • Product descriptionDecernotinib 99.45%
  • Packaging25mg
  • Price$324
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3990
  • Product descriptionDecernotinib 99.45%
  • Packaging50mg
  • Price$600
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4499DP Decernotinib 10mg $268 2021-12-16 Buy
AK Scientific 4499DP Decernotinib 25mg $479 2021-12-16 Buy
American Custom Chemicals Corporation API0024520 DECERNOTINIB 95.00% 5MG $497.95 2021-12-16 Buy
ApexBio Technology B5929 Decernotinib(VX-509) 2mg $70 2021-12-16 Buy
ApexBio Technology B5929 Decernotinib(VX-509) 5mg $95 2021-12-16 Buy
ApexBio Technology B5929 Decernotinib(VX-509) 10mM(in 1mL DMSO) $120 2021-12-16 Buy
ApexBio Technology B5929 Decernotinib(VX-509) 25mg $280 2021-12-16 Buy
Cayman Chemical 19513 VX-509 ≥98% 1mg $36 2024-03-01 Buy
Cayman Chemical 19513 VX-509 ≥98% 5mg $120 2024-03-01 Buy
Cayman Chemical 19513 VX-509 ≥98% 10mg $172 2024-03-01 Buy
Cayman Chemical 19513 VX-509 ≥98% 25mg $384 2024-03-01 Buy
ChemScene CS-3990 Decernotinib 99.45% 2mg $72 2021-12-16 Buy
ChemScene CS-3990 Decernotinib 99.45% 5mg $108 2021-12-16 Buy
ChemScene CS-3990 Decernotinib 99.45% 10mg $180 2021-12-16 Buy
ChemScene CS-3990 Decernotinib 99.45% 25mg $324 2021-12-16 Buy
ChemScene CS-3990 Decernotinib 99.45% 50mg $600 2021-12-16 Buy

Properties

Density :1.363±0.06 g/cm3(Predicted)
storage temp. :4°C, protect from light, stored under nitrogen
solubility :insoluble in H2O; ≥16.95 mg/mL in DMSO; ≥2.92 mg/mL in EtOH with ultrasonic
form :solid
pka :12.36±0.40(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P501 Dispose of contents/container to..…

Description

VX-509 is a selective inhibitor of Janus kinase 3 (JAK3) with a Ki value of 2.5 nM in enzyme assays and an IC50 value of 50-170 nM in cellular assays dependent on JAK3 activity with no measurable activity against other JAK isotypes. At 10-100 mg/kg, it has been shown to dose dependently reduce proinflammatory responses in a rat collagen-induced arthritis model and a mouse model of oxazolone-induced delayed-type hypersensitivity.

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