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ChemicalBook >> CAS DataBase List >> ARRY-334543

ARRY-334543

ARRY-334543 price.
  • $44 - $2700
  • Product name: ARRY-334543
  • CAS: 845272-21-1
  • MF: C22H19ClN6O2S
  • MW: 466.94
  • EINECS:
  • MDL Number:MFCD20275099
  • Synonyms:ARRY-334543;AR-00334543;Varlitinib;(R)-4-[[3-Chloro-4-[(thiazol-2-yl)methoxy]phenyl]amino]-6-[(4-methyl-4,5-dihydrooxazol-2-yl)amino]quinazoline;(R)-N4-(3-chloro-4-(thiazol-2-ylmethoxy)phenyl)-N6-(4-methyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine;Varlitinib ARRY 334543;ARRY 334543 (Varlitinib);N4-[3-chloro-4-(2-thiazolylmethoxy)phenyl]-N6-[(4R)-4,5-dihydro-4-methyl-2-oxazolyl]-4,6-Quinazoline diamine
19 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • TRC
Package
  • 1mg
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 1g
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0002467
  • Product description(R)-N4-(3-CHLORO-4-(THIAZOL-2-YLMETHOXY)PHENYL)-N6-(4-METHYL-4,5-DIHYDROOXAZOL-2-YL)QUINAZOLINE-4,6-DIAMINE 95.00%
  • Packaging5MG
  • Price$502.12
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8365
  • Product descriptionVarlitinib(ARRY334543)
  • Packaging5mg
  • Price$173
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number27651
  • Product descriptionVarlitinib
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27651
  • Product descriptionVarlitinib
  • Packaging5mg
  • Price$183
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27651
  • Product descriptionVarlitinib
  • Packaging10mg
  • Price$341
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27651
  • Product descriptionVarlitinib
  • Packaging25mg
  • Price$745
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5222
  • Product descriptionVarlitinib ≥98.0%
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5222
  • Product descriptionVarlitinib ≥98.0%
  • Packaging10mg
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5222
  • Product descriptionVarlitinib ≥98.0%
  • Packaging50mg
  • Price$470
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5222
  • Product descriptionVarlitinib ≥98.0%
  • Packaging100mg
  • Price$780
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000651
  • Product descriptionVarlitinib 98+%
  • Packaging5mg
  • Price$126
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000651
  • Product descriptionVarlitinib 98+%
  • Packaging10mg
  • Price$196
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000651
  • Product descriptionVarlitinib 98+%
  • Packaging50mg
  • Price$567
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000651
  • Product descriptionVarlitinib 98+%
  • Packaging100mg
  • Price$770
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8486
  • Product descriptionVarlitinib(ARRY-334543) >98%
  • Packaging1g
  • Price$2700
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number62578
  • Product descriptionVarlitinib
  • Packaging5mg
  • Price$750
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation KIN0002467 (R)-N4-(3-CHLORO-4-(THIAZOL-2-YLMETHOXY)PHENYL)-N6-(4-METHYL-4,5-DIHYDROOXAZOL-2-YL)QUINAZOLINE-4,6-DIAMINE 95.00% 5MG $502.12 2021-12-16 Buy
ApexBio Technology A8365 Varlitinib(ARRY334543) 5mg $173 2021-12-16 Buy
Cayman Chemical 27651 Varlitinib 1mg $44 2024-03-01 Buy
Cayman Chemical 27651 Varlitinib 5mg $183 2024-03-01 Buy
Cayman Chemical 27651 Varlitinib 10mg $341 2024-03-01 Buy
Cayman Chemical 27651 Varlitinib 25mg $745 2024-03-01 Buy
ChemScene CS-5222 Varlitinib ≥98.0% 5mg $120 2021-12-16 Buy
ChemScene CS-5222 Varlitinib ≥98.0% 10mg $190 2021-12-16 Buy
ChemScene CS-5222 Varlitinib ≥98.0% 50mg $470 2021-12-16 Buy
ChemScene CS-5222 Varlitinib ≥98.0% 100mg $780 2021-12-16 Buy
Crysdot CD31000651 Varlitinib 98+% 5mg $126 2021-12-16 Buy
Crysdot CD31000651 Varlitinib 98+% 10mg $196 2021-12-16 Buy
Crysdot CD31000651 Varlitinib 98+% 50mg $567 2021-12-16 Buy
Crysdot CD31000651 Varlitinib 98+% 100mg $770 2021-12-16 Buy
DC Chemicals DC8486 Varlitinib(ARRY-334543) >98% 1g $2700 2021-12-16 Buy
Medical Isotopes, Inc. 62578 Varlitinib 5mg $750 2021-12-16 Buy

Properties

Boiling point :637.1±65.0 °C(Predicted)
Density :1.51±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO : 50 mg/mL (107.08 mM; Need ultrasonic)
form :Powder
pka :6.54±0.70(Predicted)
color :Off-white to yellow
CAS DataBase Reference :845272-21-1

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330 Rinse mouth.
P391 Collect spillage. Hazardous to the aquatic environment
P501 Dispose of contents/container to..…

Description

ARRY334543 is a selective and potent ErbB1 and ErbB2 inhibitor with IC50 of 7 nM and 2 nM, respectively.

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