CCT 018159
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- $29 - $711
- Product name: CCT 018159
- CAS: 171009-07-7
- MF: C20H20N2O4
- MW: 352.38
- EINECS:
- MDL Number:MFCD00710300
- Synonyms:CCT 018159;4-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-methyl-1H-pyrazol-3-yl]-6-ethyl-1,3-benzenediol;HSP90 Inhibitor, CCT018159 - CAS 171009-07-7 - Calbiochem;1,3-Benzenediol, 4-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methyl-1H-pyrazol-3-yl]-6-ethyl-;4-(4-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-5-methyl-1H-pyrazol-3-yl)-6-ethylbenzene-1,3-diol;CCT 018159, Hsp90 ATPase inhibitor
15 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- CSNpharm
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 50
- 1MG
- 5mg
- 10mg
- 50mg
- ManufacturerAK Scientific
- Product number9331BA
- Product description4-[4-(2,3-Dihydro-1,4-benzodioxin-6-YL)-3-methyl-1H-pyrazol-5-YL]-6-ethylbenzene-1,3-diol
- Packaging5mg
- Price$179
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number9331BA
- Product description4-[4-(2,3-Dihydro-1,4-benzodioxin-6-YL)-3-methyl-1H-pyrazol-5-YL]-6-ethylbenzene-1,3-diol
- Packaging10mg
- Price$240
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0004033
- Product description4-(4-(2,3-DIHYDROBENZO[B][1,4]DIOXIN-6-YL)-5-METHYL-1H-PYRAZOL-3-YL)-6-ETHYLBENZENE-1,3-DIOL 95.00%
- Packaging1MG
- Price$137.55
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0004033
- Product description4-(4-(2,3-DIHYDROBENZO[B][1,4]DIOXIN-6-YL)-5-METHYL-1H-PYRAZOL-3-YL)-6-ETHYLBENZENE-1,3-DIOL 95.00%
- Packaging5MG
- Price$499.8
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3212
- Product descriptionCCT018159
- Packaging10mg
- Price$145
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10012591
- Product descriptionCCT018159 ≥98%
- Packaging1mg
- Price$29
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10012591
- Product descriptionCCT018159 ≥98%
- Packaging5mg
- Price$85
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10012591
- Product descriptionCCT018159 ≥98%
- Packaging10mg
- Price$156
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10012591
- Product descriptionCCT018159 ≥98%
- Packaging50mg
- Price$492
- Updated2022-04-27
- Buy
- ManufacturerCSNpharm
- Product numberCSN22743
- Product descriptionCCT018159
- Packaging10mg
- Price$128
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product number385920
- Product descriptionHSP90 Inhibitor, CCT018159 - CAS 171009-07-7 - Calbiochem
The HSP90 Inhibitor, CCT018159, also referenced under CAS 171009-07-7, controls the biological activity of HSP90. - Packaging5mg
- Price$230
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number2435
- Product descriptionCCT018159 ≥98%(HPLC)
- Packaging10
- Price$170
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number2435
- Product descriptionCCT018159 ≥98%(HPLC)
- Packaging50
- Price$711
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberC227958
- Product descriptionCCT018159
- Packaging10mg
- Price$115
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number254905
- Product descriptionCCT 018159
- Packaging10mg
- Price$409
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 9331BA | 4-[4-(2,3-Dihydro-1,4-benzodioxin-6-YL)-3-methyl-1H-pyrazol-5-YL]-6-ethylbenzene-1,3-diol | 5mg | $179 | 2021-12-16 | Buy |
| AK Scientific | 9331BA | 4-[4-(2,3-Dihydro-1,4-benzodioxin-6-YL)-3-methyl-1H-pyrazol-5-YL]-6-ethylbenzene-1,3-diol | 10mg | $240 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0004033 | 4-(4-(2,3-DIHYDROBENZO[B][1,4]DIOXIN-6-YL)-5-METHYL-1H-PYRAZOL-3-YL)-6-ETHYLBENZENE-1,3-DIOL 95.00% | 1MG | $137.55 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0004033 | 4-(4-(2,3-DIHYDROBENZO[B][1,4]DIOXIN-6-YL)-5-METHYL-1H-PYRAZOL-3-YL)-6-ETHYLBENZENE-1,3-DIOL 95.00% | 5MG | $499.8 | 2021-12-16 | Buy |
| ApexBio Technology | C3212 | CCT018159 | 10mg | $145 | 2021-12-16 | Buy |
| Cayman Chemical | 10012591 | CCT018159 ≥98% | 1mg | $29 | 2024-03-01 | Buy |
| Cayman Chemical | 10012591 | CCT018159 ≥98% | 5mg | $85 | 2024-03-01 | Buy |
| Cayman Chemical | 10012591 | CCT018159 ≥98% | 10mg | $156 | 2024-03-01 | Buy |
| Cayman Chemical | 10012591 | CCT018159 ≥98% | 50mg | $492 | 2022-04-27 | Buy |
| CSNpharm | CSN22743 | CCT018159 | 10mg | $128 | 2021-12-16 | Buy |
| Sigma-Aldrich | 385920 | HSP90 Inhibitor, CCT018159 - CAS 171009-07-7 - Calbiochem The HSP90 Inhibitor, CCT018159, also referenced under CAS 171009-07-7, controls the biological activity of HSP90. |
5mg | $230 | 2024-03-01 | Buy |
| Tocris | 2435 | CCT018159 ≥98%(HPLC) | 10 | $170 | 2021-12-16 | Buy |
| Tocris | 2435 | CCT018159 ≥98%(HPLC) | 50 | $711 | 2021-12-16 | Buy |
| TRC | C227958 | CCT018159 | 10mg | $115 | 2021-12-16 | Buy |
| Usbiological | 254905 | CCT 018159 | 10mg | $409 | 2021-12-16 | Buy |
Properties
Boiling point :547.3±50.0 °C(Predicted)
Density :1.322±0.06 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :≤30mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide
pka :8.84±0.48(Predicted)
form :White solid
color :White to off-white
Density :1.322±0.06 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :≤30mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide
pka :8.84±0.48(Predicted)
form :White solid
color :White to off-white
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
CCT 018159 is a cell-permeable pyrazoloresorcinol compound that inhibits Hsp90 ATPase activity (IC50 = 3.2 μM and 6.6 μM against human HSP 90 beta and yeast Hsp90, respectively) by targeting the enzyme's N-terminal ATP binding site. CCT 018159 exhibits no detectable effects against human HSP 70 or topoisomerase II even at concentrations as high as 100 μM and inhibits a panel of 20 commonly studied kinases only at much higher concentrations. Unlike 17-AAG , the antitumor activity of CCT018159 is not affected by the expression of NQ01/DT-diaphorase or P-glycoprotein.More related product prices
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