C 646
- $7 - $1500
- Product name: C 646
- CAS: 328968-36-1
- MF: C24H19N3O6
- MW: 445.42
- EINECS:
- MDL Number:MFCD01784780
- Synonyms:C 646;(E)-4-(4-((5-(4,5-diMethyl-2-nitrophenyl)furan-2-yl)Methylene)-3-Methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid;(Z)-4-(4-((5-(4,5-diMethyl-2-nitrophenyl)furan-2-yl)Methylene)-3-Methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid;4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]-benzoic acid;Benzoic acid, 4-[4-[[5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]-;4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]-benzoic acid C646;C 646 4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]-benzoic acid;C646, p300/CBP Inhibitor
36 prices
Selected condition:
Brand
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- Arctom
- Axon Medchem
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 2mg
- 10
- 1mg
- 5MG
- 10mg
- 25MG
- 50
- 50mg
- 100MG
- 250mg
- 1g
- ManufacturerACHEMBLOCK
- Product numberO32800
- Product description(Z)-4-(4-((5-(4,5-Dimethyl-2-nitrophenyl)furan-2-yl)methylene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoicacid 98%
- Packaging5MG
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerACHEMBLOCK
- Product numberO32800
- Product description(Z)-4-(4-((5-(4,5-Dimethyl-2-nitrophenyl)furan-2-yl)methylene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoicacid 98%
- Packaging25MG
- Price$145
- Updated2021-12-16
- Buy
- ManufacturerACHEMBLOCK
- Product numberO32800
- Product description(Z)-4-(4-((5-(4,5-Dimethyl-2-nitrophenyl)furan-2-yl)methylene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoicacid 98%
- Packaging100MG
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3508-M001
- Product descriptionC646 ≥98%(NMR)
- Packaging1mg
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2295AH
- Product description4-[(4Z)-4-[[5-(4,5-Dimethyl-2-nitrophenyl)furan-2-yl]methylidene]-3-methyl-5-oxopyrazol-1-yl]benzoicacid
- Packaging1mg
- Price$88
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2295AH
- Product description4-[(4Z)-4-[[5-(4,5-Dimethyl-2-nitrophenyl)furan-2-yl]methylidene]-3-methyl-5-oxopyrazol-1-yl]benzoicacid
- Packaging10mg
- Price$184
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA122218
- Product descriptionC646 98+%
- Packaging1mg
- Price$7
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA122218
- Product descriptionC646 98+%
- Packaging5mg
- Price$14
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA122218
- Product descriptionC646 98+%
- Packaging10mg
- Price$21
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA122218
- Product descriptionC646 98+%
- Packaging50mg
- Price$52
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA122218
- Product descriptionC646 98+%
- Packaging100mg
- Price$77
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA122218
- Product descriptionC646 98+%
- Packaging250mg
- Price$129
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA122218
- Product descriptionC646 98+%
- Packaging1g
- Price$318
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0305948
- Product description4-[4-[[5-(4,5-DIMETHYL-2-NITROPHENYL)-2-FURANYL]METHYLENE]-4,5-DIHYDRO-3-METHYL-5-OXO-1H-PYRAZOL-1-YL]BENZOIC ACID 95.00%
- Packaging5MG
- Price$501.81
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60146
- Product descriptionC646 ≥98%
- Packaging10mg
- Price$188
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1781
- Product descriptionC646 99%
- Packaging2mg
- Price$66
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
ACHEMBLOCK | O32800 | (Z)-4-(4-((5-(4,5-Dimethyl-2-nitrophenyl)furan-2-yl)methylene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoicacid 98% | 5MG | $65 | 2021-12-16 | Buy |
ACHEMBLOCK | O32800 | (Z)-4-(4-((5-(4,5-Dimethyl-2-nitrophenyl)furan-2-yl)methylene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoicacid 98% | 25MG | $145 | 2021-12-16 | Buy |
ACHEMBLOCK | O32800 | (Z)-4-(4-((5-(4,5-Dimethyl-2-nitrophenyl)furan-2-yl)methylene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoicacid 98% | 100MG | $450 | 2021-12-16 | Buy |
Adipogen Life Sciences | AG-CR1-3508-M001 | C646 ≥98%(NMR) | 1mg | $30 | 2021-12-16 | Buy |
AK Scientific | 2295AH | 4-[(4Z)-4-[[5-(4,5-Dimethyl-2-nitrophenyl)furan-2-yl]methylidene]-3-methyl-5-oxopyrazol-1-yl]benzoicacid | 1mg | $88 | 2021-12-16 | Buy |
AK Scientific | 2295AH | 4-[(4Z)-4-[[5-(4,5-Dimethyl-2-nitrophenyl)furan-2-yl]methylidene]-3-methyl-5-oxopyrazol-1-yl]benzoicacid | 10mg | $184 | 2021-12-16 | Buy |
Ambeed | A122218 | C646 98+% | 1mg | $7 | 2021-12-16 | Buy |
Ambeed | A122218 | C646 98+% | 5mg | $14 | 2021-12-16 | Buy |
Ambeed | A122218 | C646 98+% | 10mg | $21 | 2021-12-16 | Buy |
Ambeed | A122218 | C646 98+% | 50mg | $52 | 2021-12-16 | Buy |
Ambeed | A122218 | C646 98+% | 100mg | $77 | 2021-12-16 | Buy |
Ambeed | A122218 | C646 98+% | 250mg | $129 | 2021-12-16 | Buy |
Ambeed | A122218 | C646 98+% | 1g | $318 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | CHM0305948 | 4-[4-[[5-(4,5-DIMETHYL-2-NITROPHENYL)-2-FURANYL]METHYLENE]-4,5-DIHYDRO-3-METHYL-5-OXO-1H-PYRAZOL-1-YL]BENZOIC ACID 95.00% | 5MG | $501.81 | 2021-12-16 | Buy |
Arctom | CFN60146 | C646 ≥98% | 10mg | $188 | 2021-12-16 | Buy |
Axon Medchem | Axon1781 | C646 99% | 2mg | $66 | 2021-12-16 | Buy |
Properties
Melting point :224-226℃
Boiling point :662.6±65.0 °C(Predicted)
Density :1.38±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >25mg/mL
form :powder
pka :4.20±0.10(Predicted)
color :red to brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
InChIKey :HEKJYZZSCQBJGB-XDHOZWIPSA-N
Boiling point :662.6±65.0 °C(Predicted)
Density :1.38±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >25mg/mL
form :powder
pka :4.20±0.10(Predicted)
color :red to brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
InChIKey :HEKJYZZSCQBJGB-XDHOZWIPSA-N
Safety Information
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Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Precautionary statements: |
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Description
C646 is an inhibitor of the histone acetyltransferase p300 (IC50 = 1.6 μM). It competitively (versus acetyl-CoA) binds p300 (Ki = 400 nM) and does not inhibit several other acetyltransferases. The action of C646 appears to be irreversible through covalent modification of the enzyme target. It blocks the growth of human melanoma, leukemia, lung, and prostate cancer cells in vitro. C646 has been used to study the role of p300-mediated acetylation in such models as fear extinction memory and the regulation of immediate-early genes.More related product prices
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Suppliers and manufacturers
career henan chemical co
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Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd
Dideu Industries Group Limited
Baoji Guokang Bio-Technology Co., Ltd.
Zhejiang J&C Biological Technology Co.,Limited
$1.00 /1KG
4-[(4Z)-4-[[5-(4,5-dimethyl-2-nitrophenyl)furan-2-yl]methylidene]-3-methyl-5-oxopyrazol-1-yl]benzoic acid CAS:328968-36-1
4-[(4Z)-4-[[5-(4,5-dimethyl-2-nitrophenyl)furan-2-yl]methylidene]-3-methyl-5-oxopyrazol-1-yl]benzoic acid CAS:328968-36-1