BMS 303141
- $30 - $2691.1
- Product name: BMS 303141
- CAS: 943962-47-8
- MF: C19H15Cl2NO4S
- MW: 424.3
- EINECS:
- MDL Number:MFCD25976797
- Synonyms:BMS 303141;BMS30314;3,5-dichloro-2-hydroxy-N-(4-Methoxybiphenyl-3-yl)benzenesulfonaMide;3,5-Dichloro-2-hydroxy-N-(4-methoxy[1,1'-biphenyl]-3-yl)benzenesulfonamide;3,5-Dichloro-2-hydroxy-N-(4-methoxy[1,1'-biphenyl]-3-yl)-benzenesulfonamide BMS 303141;BMS 303141, >=98%;3,5-dichloro-2-hydroxy-N-(2-methoxy-5-phenylphenyl)benzenesulfonamide;CS-887
39 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 50
- 1mg
- 5mg
- 10
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1000mg
- 1g
- 10mM(in 1mL DMSO)
- ManufacturerAK Scientific
- Product number3497AH
- Product descriptionBMS-303141
- Packaging250mg
- Price$397
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169881
- Product description3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+%
- Packaging1mg
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169881
- Product description3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+%
- Packaging5mg
- Price$51
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169881
- Product description3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+%
- Packaging10mg
- Price$66
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169881
- Product description3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+%
- Packaging50mg
- Price$112
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169881
- Product description3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+%
- Packaging100mg
- Price$163
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169881
- Product description3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+%
- Packaging250mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169881
- Product description3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+%
- Packaging1g
- Price$631
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0009814
- Product descriptionBMS-303141 95.00%
- Packaging5MG
- Price$451.43
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1079
- Product descriptionBMS-303141
- Packaging10mM(in 1mL DMSO)
- Price$72
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1079
- Product descriptionBMS-303141
- Packaging10mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1079
- Product descriptionBMS-303141
- Packaging25mg
- Price$170
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1079
- Product descriptionBMS-303141
- Packaging50mg
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2506
- Product descriptionBMS303141 100%
- Packaging50mg
- Price$319
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545898
- Product descriptionbMS-303141 >98%
- Packaging5mg
- Price$190.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545898
- Product descriptionbMS-303141 >98%
- Packaging25mg
- Price$521.9
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 3497AH | BMS-303141 | 250mg | $397 | 2021-12-16 | Buy |
Ambeed | A169881 | 3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+% | 1mg | $30 | 2021-12-16 | Buy |
Ambeed | A169881 | 3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+% | 5mg | $51 | 2021-12-16 | Buy |
Ambeed | A169881 | 3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+% | 10mg | $66 | 2021-12-16 | Buy |
Ambeed | A169881 | 3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+% | 50mg | $112 | 2021-12-16 | Buy |
Ambeed | A169881 | 3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+% | 100mg | $163 | 2021-12-16 | Buy |
Ambeed | A169881 | 3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+% | 250mg | $250 | 2021-12-16 | Buy |
Ambeed | A169881 | 3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+% | 1g | $631 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0009814 | BMS-303141 95.00% | 5MG | $451.43 | 2021-12-16 | Buy |
ApexBio Technology | B1079 | BMS-303141 | 10mM(in 1mL DMSO) | $72 | 2021-12-16 | Buy |
ApexBio Technology | B1079 | BMS-303141 | 10mg | $85 | 2021-12-16 | Buy |
ApexBio Technology | B1079 | BMS-303141 | 25mg | $170 | 2021-12-16 | Buy |
ApexBio Technology | B1079 | BMS-303141 | 50mg | $300 | 2021-12-16 | Buy |
Axon Medchem | Axon2506 | BMS303141 100% | 50mg | $319 | 2021-12-16 | Buy |
Biorbyt Ltd | orb545898 | bMS-303141 >98% | 5mg | $190.4 | 2021-12-16 | Buy |
Biorbyt Ltd | orb545898 | bMS-303141 >98% | 25mg | $521.9 | 2021-12-16 | Buy |
Properties
Boiling point :591.5±60.0 °C(Predicted)
Density :1.462±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
pka :4.94±0.48(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Density :1.462±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
pka :4.94±0.48(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Safety Information
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Description
ATP citrate lyase (ACL) catalyzes the synthesis of acetyl-CoA and oxaloacetate using citrate, CoA, and ATP as substrates and Mg2+ as a cofactor. The ACL-dependent synthesis of acetyl-CoA is important for the de novo synthesis of fatty acids and cholesterol. Furthermore, as a key enzyme for linking glucose and lipid metabolism, ACL is thought to contribute to the Warburg effect in cancer cells. BMS 303141 is a cell-permeable, 2-hydroxy-N-arylbenzenesulfonamide that inhibits ACL with an IC50 value of 0.13 μM. At an oral dose of 100 mg/kg/day, BMS 303141 has been reported to reduce weight gain and lower plasma cholesterol, triglycerides, and glucose in a mouse model of hyperlipidemia.More related product prices
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Suppliers and manufacturers
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