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ChemicalBook >> CAS DataBase List >> METYRAPONE

METYRAPONE

METYRAPONE price.
  • $20 - $729
  • Product name: METYRAPONE
  • CAS: 54-36-4
  • MF: C14H14N2O
  • MW: 226.27
  • EINECS:200-206-2
  • MDL Number:MFCD00006397
  • Synonyms:Metapirone;Metapyrone;Methapyrapone;Methbipyranone;Methopirapone;Methopyrapone;Methopyrinine;Methopyrone
23 prices
Selected condition：
Brand
  • AHH
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10mg
  • 50mg
  • 250mg
  • 5g
  • 10g
  • 50
  • 25mg
  • 100mg
  • 200mg
  • 500mg
  • 1g
  • 25g
  • ManufacturerAHH
  • Product numberMT-54292
  • Product descriptionMetyrapone 96%
  • Packaging25g
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberW6860
  • Product description2-Methyl-1,2-di-3-pyridyl-1-propanone
  • Packaging500mg
  • Price$145
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberW6860
  • Product description2-Methyl-1,2-di-3-pyridyl-1-propanone
  • Packaging1g
  • Price$182
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA341725
  • Product description2-Methyl-1,2-di(pyridin-3-yl)propan-1-one 95+%
  • Packaging25mg
  • Price$20
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA341725
  • Product description2-Methyl-1,2-di(pyridin-3-yl)propan-1-one 95+%
  • Packaging100mg
  • Price$29
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA341725
  • Product description2-Methyl-1,2-di(pyridin-3-yl)propan-1-one 95+%
  • Packaging1g
  • Price$188
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA341725
  • Product description2-Methyl-1,2-di(pyridin-3-yl)propan-1-one 95+%
  • Packaging5g
  • Price$729
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003315
  • Product descriptionMETYRAPONE 95.00%
  • Packaging1G
  • Price$642.47
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7347
  • Product descriptionMetyrapone
  • Packaging50mg
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14994
  • Product descriptionMetyrapone ≥98%
  • Packaging250mg
  • Price$25
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14994
  • Product descriptionMetyrapone ≥98%
  • Packaging500mg
  • Price$43
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14994
  • Product descriptionMetyrapone ≥98%
  • Packaging1g
  • Price$76
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM170969
  • Product description2-Methyl-1,2-di-3-pyridyl-1-propanone 97%
  • Packaging10g
  • Price$650
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4879
  • Product descriptionMetyrapone 99.84%
  • Packaging500mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number856525
  • Product description2-Methyl-1,2-di-3-pyridyl-1-propanone 96%
  • Packaging250mg
  • Price$48.5
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberM2696
  • Product descriptionMetyrapone ≥98% (HPLC), solid
  • Packaging10mg
  • Price$82.3
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-54292 Metyrapone 96% 25g $250 2021-12-16 Buy
AK Scientific W6860 2-Methyl-1,2-di-3-pyridyl-1-propanone 500mg $145 2021-12-16 Buy
AK Scientific W6860 2-Methyl-1,2-di-3-pyridyl-1-propanone 1g $182 2021-12-16 Buy
Ambeed A341725 2-Methyl-1,2-di(pyridin-3-yl)propan-1-one 95+% 25mg $20 2021-12-16 Buy
Ambeed A341725 2-Methyl-1,2-di(pyridin-3-yl)propan-1-one 95+% 100mg $29 2021-12-16 Buy
Ambeed A341725 2-Methyl-1,2-di(pyridin-3-yl)propan-1-one 95+% 1g $188 2021-12-16 Buy
Ambeed A341725 2-Methyl-1,2-di(pyridin-3-yl)propan-1-one 95+% 5g $729 2021-12-16 Buy
American Custom Chemicals Corporation API0003315 METYRAPONE 95.00% 1G $642.47 2021-12-16 Buy
ApexBio Technology B7347 Metyrapone 50mg $40 2021-12-16 Buy
Cayman Chemical 14994 Metyrapone ≥98% 250mg $25 2024-03-01 Buy
Cayman Chemical 14994 Metyrapone ≥98% 500mg $43 2024-03-01 Buy
Cayman Chemical 14994 Metyrapone ≥98% 1g $76 2024-03-01 Buy
Chemenu CM170969 2-Methyl-1,2-di-3-pyridyl-1-propanone 97% 10g $650 2021-12-16 Buy
ChemScene CS-4879 Metyrapone 99.84% 500mg $60 2021-12-16 Buy
Sigma-Aldrich 856525 2-Methyl-1,2-di-3-pyridyl-1-propanone 96% 250mg $48.5 2024-03-01 Buy
Sigma-Aldrich M2696 Metyrapone ≥98% (HPLC), solid 10mg $82.3 2024-03-01 Buy

Properties

Melting point :52-55 °C(lit.)
Boiling point :367.89°C (rough estimate)
Density :1.0852 (rough estimate)
refractive index :1.6419 (estimate)
Flash point :>230 °F
storage temp. :Inert atmosphere,Room Temperature
solubility :H2O: soluble (sparingly)
form :solid
pka :4.61±0.10(Predicted)
color :White
Merck :13,6181
BRN :163023
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
EPA Substance Registry System :Metyrapone (54-36-4)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Metyrapone blocks cortisol synthesis by inhibiting steroid 11β-hydroxylase in adrenal cortex (IC50 = 7.8 μM). Metyrapone binds with high affinity to cytochrome P(CYP)450 in hepatic microsomes and induces rat hepatic CYP1A1 and CYP3A gene expression. It is used to assess adrenal insufficiency, to address hypercortisolism characteristic of Cushing’s syndrome, and may be of clinical value in the treatment of depression and in reducing brain damage resulting from hypoxia-ischemia.

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