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ChemicalBook >> CAS DataBase List >> BMS813160

BMS813160

BMS813160 price.
  • $140 - $1950
  • Product name: BMS813160
  • CAS: 1286279-29-5
  • MF: C25H40N8O2
  • MW: 484.64
  • EINECS:-0
  • MDL Number:MFCD31540731
  • Synonyms:CS-2742;BMS-813160;BMS813160;BMS 813160;N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-3-(7-tert-butylpyrazolo[1,5-a][1,3,5]triazin-4-ylamino)-2-oxopyrrolidin-1-yl)cyclohexyl)acetamide;BMS813160;Acetamide, N-[(1R,2S,5R)-5-[(1,1-dimethylethyl)amino]-2-[(3S)-3-[[7-(1,1-dimethylethyl)pyrazolo[1,5-a]-1,3,5-triazin-4-yl]amino]-2-oxo-1-pyrrolidinyl]cyclohexyl]-;Inhibitor,CC chemokine receptor,CCR,dual antagonist,peritonitis,CD11b,BMS-813160,inflammation,CTX,thioglycollate,BMS813160,inhibit,mouse,oral;BMS-813160, 10 mM in DMSO;BMS-585059
10 prices
Selected condition：
Brand
  • AK Scientific
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number8980DH
  • Product descriptionN-[(1R,2S,5R)-5-(Tert-butylamino)-2-[(3S)-3-[(7-tert-butylpyrazolo[1,5-a][1,3,5]triazin-4-yl)amino]-2-oxopyrrolidin-1-yl]cyclohexyl]acetamide
  • Packaging5mg
  • Price$1174
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number28421
  • Product descriptionBMS 813160
  • Packaging1mg
  • Price$242
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28421
  • Product descriptionBMS 813160
  • Packaging5mg
  • Price$965
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0033469
  • Product descriptionBMS-813160 99.89%
  • Packaging2mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0033469
  • Product descriptionBMS-813160 99.89%
  • Packaging5mg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0033469
  • Product descriptionBMS-813160 99.89%
  • Packaging10mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0033469
  • Product descriptionBMS-813160 99.89%
  • Packaging50mg
  • Price$1350
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0033469
  • Product descriptionBMS-813160 99.89%
  • Packaging100mg
  • Price$1950
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10494
  • Product descriptionBMS813160 >98%
  • Packaging100mg
  • Price$650
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberB595925
  • Product descriptionBMS-813160
  • Packaging1mg
  • Price$305
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8980DH N-[(1R,2S,5R)-5-(Tert-butylamino)-2-[(3S)-3-[(7-tert-butylpyrazolo[1,5-a][1,3,5]triazin-4-yl)amino]-2-oxopyrrolidin-1-yl]cyclohexyl]acetamide 5mg $1174 2021-12-16 Buy
Cayman Chemical 28421 BMS 813160 1mg $242 2024-03-01 Buy
Cayman Chemical 28421 BMS 813160 5mg $965 2024-03-01 Buy
ChemScene CS-0033469 BMS-813160 99.89% 2mg $140 2021-12-16 Buy
ChemScene CS-0033469 BMS-813160 99.89% 5mg $280 2021-12-16 Buy
ChemScene CS-0033469 BMS-813160 99.89% 10mg $450 2021-12-16 Buy
ChemScene CS-0033469 BMS-813160 99.89% 50mg $1350 2021-12-16 Buy
ChemScene CS-0033469 BMS-813160 99.89% 100mg $1950 2021-12-16 Buy
DC Chemicals DC10494 BMS813160 >98% 100mg $650 2021-12-16 Buy
TRC B595925 BMS-813160 1mg $305 2021-12-16 Buy

Properties

Density :1.31±0.1 g/cm3(Predicted)
storage temp. :4°C, protect from light
solubility :DMSO:61.0(Max Conc. mg/mL);125.86(Max Conc. mM)
Ethanol:97.0(Max Conc. mg/mL);200.14(Max Conc. mM) form :A crystalline solid
pka :15.46±0.60(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P307+P311, P321,P405, P501
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P341 IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P310 Immediately call a POISON CENTER or doctor/physician.
P321 Specific treatment (see … on this label).
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.
P342+P311 IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P363 Wash contaminated clothing before reuse.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

BMS 813160 is a dual antagonist of chemokine receptor 2 (CCR2) and CCR5 (IC50s = 6.2 and 3.6 nM, respectively, in radioligand binding assays). It inhibits chemotaxis induced by the CCR2 ligand MCP-1 in THP-1 cells the CCR5 ligand MIP-1β in isolated peripheral T cells with IC50 values of 0.8 and 1.1 nM, respectively. BMS 813160 inhibits peritoneal monocyte and macrophage infiltration in an hCCR-2 KI mouse model of thioglycolate-induced peritonitis, with 54% inhibition when administered at a dose of 50 mg/kg twice per day.

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