BMS813160
- $140 - $1950
- Product name: BMS813160
- CAS: 1286279-29-5
- MF: C25H40N8O2
- MW: 484.64
- EINECS:-0
- MDL Number:MFCD31540731
- Synonyms:CS-2742;BMS-813160;BMS813160;BMS 813160;N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-3-(7-tert-butylpyrazolo[1,5-a][1,3,5]triazin-4-ylamino)-2-oxopyrrolidin-1-yl)cyclohexyl)acetamide;BMS813160;Acetamide, N-[(1R,2S,5R)-5-[(1,1-dimethylethyl)amino]-2-[(3S)-3-[[7-(1,1-dimethylethyl)pyrazolo[1,5-a]-1,3,5-triazin-4-yl]amino]-2-oxo-1-pyrrolidinyl]cyclohexyl]-;Inhibitor,CC chemokine receptor,CCR,dual antagonist,peritonitis,CD11b,BMS-813160,inflammation,CTX,thioglycollate,BMS813160,inhibit,mouse,oral
10 prices
Selected condition:
Brand
- AK Scientific
- Cayman Chemical
- ChemScene
- DC Chemicals
- TRC
Package
- 1mg
- 2mg
- 5mg
- 10mg
- 50mg
- 100mg
- ManufacturerAK Scientific
- Product number8980DH
- Product descriptionN-[(1R,2S,5R)-5-(Tert-butylamino)-2-[(3S)-3-[(7-tert-butylpyrazolo[1,5-a][1,3,5]triazin-4-yl)amino]-2-oxopyrrolidin-1-yl]cyclohexyl]acetamide
- Packaging5mg
- Price$1174
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number28421
- Product descriptionBMS 813160
- Packaging1mg
- Price$242
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28421
- Product descriptionBMS 813160
- Packaging5mg
- Price$965
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0033469
- Product descriptionBMS-813160 99.89%
- Packaging2mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0033469
- Product descriptionBMS-813160 99.89%
- Packaging5mg
- Price$280
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0033469
- Product descriptionBMS-813160 99.89%
- Packaging10mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0033469
- Product descriptionBMS-813160 99.89%
- Packaging50mg
- Price$1350
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0033469
- Product descriptionBMS-813160 99.89%
- Packaging100mg
- Price$1950
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10494
- Product descriptionBMS813160 >98%
- Packaging100mg
- Price$650
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberB595925
- Product descriptionBMS-813160
- Packaging1mg
- Price$305
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 8980DH | N-[(1R,2S,5R)-5-(Tert-butylamino)-2-[(3S)-3-[(7-tert-butylpyrazolo[1,5-a][1,3,5]triazin-4-yl)amino]-2-oxopyrrolidin-1-yl]cyclohexyl]acetamide | 5mg | $1174 | 2021-12-16 | Buy |
Cayman Chemical | 28421 | BMS 813160 | 1mg | $242 | 2024-03-01 | Buy |
Cayman Chemical | 28421 | BMS 813160 | 5mg | $965 | 2024-03-01 | Buy |
ChemScene | CS-0033469 | BMS-813160 99.89% | 2mg | $140 | 2021-12-16 | Buy |
ChemScene | CS-0033469 | BMS-813160 99.89% | 5mg | $280 | 2021-12-16 | Buy |
ChemScene | CS-0033469 | BMS-813160 99.89% | 10mg | $450 | 2021-12-16 | Buy |
ChemScene | CS-0033469 | BMS-813160 99.89% | 50mg | $1350 | 2021-12-16 | Buy |
ChemScene | CS-0033469 | BMS-813160 99.89% | 100mg | $1950 | 2021-12-16 | Buy |
DC Chemicals | DC10494 | BMS813160 >98% | 100mg | $650 | 2021-12-16 | Buy |
TRC | B595925 | BMS-813160 | 1mg | $305 | 2021-12-16 | Buy |
Properties
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :4°C, protect from light
solubility :DMSO:61.0(Max Conc. mg/mL);125.86(Max Conc. mM)
Ethanol:97.0(Max Conc. mg/mL);200.14(Max Conc. mM) form :A crystalline solid
pka :15.46±0.60(Predicted)
color :White to off-white
storage temp. :4°C, protect from light
solubility :DMSO:61.0(Max Conc. mg/mL);125.86(Max Conc. mM)
Ethanol:97.0(Max Conc. mg/mL);200.14(Max Conc. mM) form :A crystalline solid
pka :15.46±0.60(Predicted)
color :White to off-white
Safety Information
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Signal word: | Danger | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Hazard statements: |
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Description
BMS 813160 is a dual antagonist of chemokine receptor 2 (CCR2) and CCR5 (IC50s = 6.2 and 3.6 nM, respectively, in radioligand binding assays). It inhibits chemotaxis induced by the CCR2 ligand MCP-1 in THP-1 cells the CCR5 ligand MIP-1β in isolated peripheral T cells with IC50 values of 0.8 and 1.1 nM, respectively. BMS 813160 inhibits peritoneal monocyte and macrophage infiltration in an hCCR-2 KI mouse model of thioglycolate-induced peritonitis, with 54% inhibition when administered at a dose of 50 mg/kg twice per day.More related product prices
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