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ChemicalBook >> CAS DataBase List >> Azathioprine

Azathioprine

Azathioprine price.
  • $13 - $1880
  • Product name: Azathioprine
  • CAS: 446-86-6
  • MF: C9H7N7O2S
  • MW: 277.26
  • EINECS:207-175-4
  • MDL Number:MFCD00069203
  • Synonyms:6-((1-methyl-4-nitro-1h-imidazol-5-yl)thio)-1h-purin ;6-((1-methyl-4-nitroimidazol-5-yl)thio)-purin ;6-(1’-methyl-4’-nitro-5’-imidazolyl)-mercaptopurine ;6-(1-Methyl-4-nitro-5-imidazolythio)-9H-pur-ine ;6-(1-methyl-4-nitroimidazol-5-ylthio)purin ;6-(1-methyl-p-nitro-5-imidazolyl)-thiopurine ;Azathioprine (200 mg);USP30/EP5 API
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  • AHH
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  • Ambeed
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  • ApexBio Technology
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  • Cayman Chemical
  • Chemenu
  • Chem-Impex
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  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
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  • a1500000
  • 25g
  • 50g
  • ManufacturerAHH
  • Product numberAPI-1241
  • Product descriptionAzathiopurine 98%
  • Packaging25g
  • Price$340
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ11494
  • Product descriptionAzathioprine
  • Packaging25mg
  • Price$49
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ62314
  • Product descriptionAzathioprine
  • Packaging1g
  • Price$102.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ62314
  • Product descriptionAzathioprine
  • Packaging5g
  • Price$327.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ62314
  • Product descriptionAzathioprine
  • Packaging10g
  • Price$704.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA101947
  • Product description6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-9H-purine 98+%
  • Packaging100mg
  • Price$13
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA101947
  • Product description6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-9H-purine 98+%
  • Packaging250mg
  • Price$19
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA101947
  • Product description6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-9H-purine 98+%
  • Packaging1g
  • Price$37
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA101947
  • Product description6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-9H-purine 98+%
  • Packaging5g
  • Price$109
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0024285
  • Product descriptionAZATHIOPRINE 95.00%
  • Packaging1G
  • Price$190.05
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0001569
  • Product description6-(3-METHYL-5-NITROIMIDAZOL-4-YL)SULFANYL-7H-PURINE 95.00%
  • Packaging100MG
  • Price$1593.9
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB1892
  • Product descriptionAzathioprine
  • Packaging1g
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS426285
  • Product description6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-9H-purine ≥98%
  • Packaging100mg
  • Price$13
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS426285
  • Product description6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-9H-purine ≥98%
  • Packaging250mg
  • Price$19
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS426285
  • Product description6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-9H-purine ≥98%
  • Packaging1g
  • Price$37
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS426285
  • Product description6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-9H-purine ≥98%
  • Packaging5g
  • Price$108
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH API-1241 Azathiopurine 98% 25g $340 2021-12-16 Buy
AK Scientific J11494 Azathioprine 25mg $49 2021-12-16 Buy
Alfa Aesar J62314 Azathioprine 1g $102.65 2024-03-01 Buy
Alfa Aesar J62314 Azathioprine 5g $327.65 2024-03-01 Buy
Alfa Aesar J62314 Azathioprine 10g $704.65 2024-03-01 Buy
Ambeed A101947 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-9H-purine 98+% 100mg $13 2021-12-16 Buy
Ambeed A101947 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-9H-purine 98+% 250mg $19 2021-12-16 Buy
Ambeed A101947 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-9H-purine 98+% 1g $37 2021-12-16 Buy
Ambeed A101947 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-9H-purine 98+% 5g $109 2021-12-16 Buy
American Custom Chemicals Corporation API0024285 AZATHIOPRINE 95.00% 1G $190.05 2021-12-16 Buy
American Custom Chemicals Corporation API0001569 6-(3-METHYL-5-NITROIMIDAZOL-4-YL)SULFANYL-7H-PURINE 95.00% 100MG $1593.9 2021-12-16 Buy
ApexBio Technology B1892 Azathioprine 1g $50 2021-12-16 Buy
Arctom AS426285 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-9H-purine ≥98% 100mg $13 2021-12-16 Buy
Arctom AS426285 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-9H-purine ≥98% 250mg $19 2021-12-16 Buy
Arctom AS426285 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-9H-purine ≥98% 1g $37 2021-12-16 Buy
Arctom AS426285 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-9H-purine ≥98% 5g $108 2021-12-16 Buy

Properties

Melting point :243-244°C
Boiling point :521.0±60.0 °C(Predicted)
Density :1.5379 (rough estimate)
refractive index :1.7400 (estimate)
storage temp. :2-8°C
solubility :Soluble in Dichloromethane and dimethyl sulfoxide.
pka :8.2(at 25℃)
form :Solid
color :Pale-yellow crystals from Me2CO (aq)
Water Solubility :<0.1 g/100 mL at 23 ºC
Merck :14,902
BCS Class :4
Stability :Stable. Incompatible with strong oxidizing agents, strong bases.
InChIKey :LMEKQMALGUDUQG-UHFFFAOYSA-N
CAS DataBase Reference :446-86-6(CAS DataBase Reference)
IARC :1 (Vol. 26, Sup 7, 100A) 2012
EPA Substance Registry System :Azathioprine (446-86-6)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Azathioprine is a purine analog with immunosuppressive effects. It serves as a prodrug for 6-mercaptopurine, which alters purine processing and DNA synthesis, interfering with the proliferation of lymphocytes and other myeloid cells. Its immunomodulating actions are used to benefit inflammatory bowel disease, as well as a wide range of additional diseases with immunological or autoimmunological components, including rheumatoid arthritis and lupus nephritis.

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