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ChemicalBook >> CAS DataBase List >> ARRY-424704, ARRY-704

ARRY-424704, ARRY-704

ARRY-424704, ARRY-704 price.
  • $62 - $9435.2
  • Product name: ARRY-424704, ARRY-704
  • CAS: 869357-68-6
  • MF: C16H17FIN3O4
  • MW: 461.23
  • EINECS:642-441-7
  • MDL Number:MFCD18384989
  • Synonyms:ARRY-424704, ARRY-704;AZD8330;2-(2-Fluoro-4-iodophenylamino)-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxamide;ARRY424704;ARRY-424704;ARRY704;ARRY-704;AZD8330/ARRY-424704/arry-704/AZD8330/AZD-8330
30 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • TRC
  • Usbiological
Package
  • 1MG
  • 5mg
  • 2.5mg
  • 10mM(in 1mL DMSO)
  • 10MG
  • 50mg
  • 2x25mg
  • 100mg
  • 200MG
  • 250mg
  • 1G
  • 5g
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1195-M005
  • Product descriptionAZD-8330 ≥95%
  • Packaging5mg
  • Price$184
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN5687
  • Product descriptionAZD8330
  • Packaging50mg
  • Price$968
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000910
  • Product descriptionAZD-8330 95.00%
  • Packaging1MG
  • Price$228.9
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000910
  • Product descriptionAZD-8330 95.00%
  • Packaging10MG
  • Price$1006.58
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000910
  • Product descriptionAZD-8330 95.00%
  • Packaging200MG
  • Price$3384.15
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000910
  • Product descriptionAZD-8330 95.00%
  • Packaging1G
  • Price$9435.2
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8374
  • Product descriptionAZD8330
  • Packaging5mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8374
  • Product descriptionAZD8330
  • Packaging10mM(in 1mL DMSO)
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8374
  • Product descriptionAZD8330
  • Packaging10mg
  • Price$224
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8374
  • Product descriptionAZD8330
  • Packaging50mg
  • Price$679
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8374
  • Product descriptionAZD8330
  • Packaging100mg
  • Price$950
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1999
  • Product descriptionAZD8330 98%
  • Packaging5mg
  • Price$115.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1999
  • Product descriptionAZD8330 98%
  • Packaging2x25mg
  • Price$616
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA103093
  • Product descriptionAZD 8330
  • Packaging10mg
  • Price$185
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA103093
  • Product descriptionAZD 8330
  • Packaging50mg
  • Price$647.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11588
  • Product descriptionAZD 8330 ≥98%
  • Packaging1mg
  • Price$62
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences SYN-1195-M005 AZD-8330 ≥95% 5mg $184 2021-12-16 Buy
AK Scientific SYN5687 AZD8330 50mg $968 2021-12-16 Buy
American Custom Chemicals Corporation INB0000910 AZD-8330 95.00% 1MG $228.9 2021-12-16 Buy
American Custom Chemicals Corporation INB0000910 AZD-8330 95.00% 10MG $1006.58 2021-12-16 Buy
American Custom Chemicals Corporation INB0000910 AZD-8330 95.00% 200MG $3384.15 2021-12-16 Buy
American Custom Chemicals Corporation INB0000910 AZD-8330 95.00% 1G $9435.2 2021-12-16 Buy
ApexBio Technology A8374 AZD8330 5mg $119 2021-12-16 Buy
ApexBio Technology A8374 AZD8330 10mM(in 1mL DMSO) $130 2021-12-16 Buy
ApexBio Technology A8374 AZD8330 10mg $224 2021-12-16 Buy
ApexBio Technology A8374 AZD8330 50mg $679 2021-12-16 Buy
ApexBio Technology A8374 AZD8330 100mg $950 2021-12-16 Buy
Axon Medchem Axon1999 AZD8330 98% 5mg $115.5 2021-12-16 Buy
Axon Medchem Axon1999 AZD8330 98% 2x25mg $616 2021-12-16 Buy
Biosynth Carbosynth FA103093 AZD 8330 10mg $185 2021-12-16 Buy
Biosynth Carbosynth FA103093 AZD 8330 50mg $647.5 2021-12-16 Buy
Cayman Chemical 11588 AZD 8330 ≥98% 1mg $62 2024-03-01 Buy

Properties

Density :1.732
storage temp. :Store at -20°C
solubility :≥23.05 mg/mL in DMSO; insoluble in H2O; ≥46.1 mg/mL in EtOH
form :solid
pka :14.31±0.10(Predicted)
color :Off-white to pink

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P314 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

AZD 8330 is a selective allosteric inhibitor of MEK1/2 (IC50 = 7 nM). It blocks phosphorylation of ERK1/2 and inhibits proliferation of certain cancer cells. AZD 8330 is orally bioavailable, inhibits ERK phosphorylation in vivo, and reduces tumor growth in a Calu-6 nude rat xenograft model.

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