BKM120 (NVP-BKM120, Buparlisib)
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- $26 - $4200
- Product name: BKM120 (NVP-BKM120, Buparlisib)
- CAS: 944396-07-0
- MF: C18H21F3N6O2
- MW: 410.39
- EINECS:
- MDL Number:MFCD18251596
- Synonyms:5-[2,6-Di(4-morpholinyl)-4-pyrimidinyl]-4-(trifluoromethyl)-2-pyridinamine;5-(2,6-diMorpholinopyriMidin-4-yl)-4-(trifluoroMethyl)pyridin-2-aMine;BKM120 (NVP-BKM120);NVP-BKM-120;BKM120 (NVP-BKM120, Buparlisib);NVP-BKM120, Buparlisib;BKM120BASE;Buparlisib
31 prices
Selected condition：
Brand
- Adipogen Life Sciences
- ApexBio Technology
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- TRC
Package
- 1unit
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 2x25mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1200-M001
- Product descriptionBKM120 ≥95%
- Packaging1mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3015
- Product descriptionBKM120
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3015
- Product descriptionBKM120
- Packaging5mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60065
- Product descriptionBuparlisib(BKM120) ≥98%
- Packaging10mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1797
- Product descriptionNVP-BKM120-BKM120|Buparlisib 98%
- Packaging2x25mg
- Price$462
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146274
- Product descriptionBKM120 (NVP-BKM120, Buparlisib) >98%
- Packaging100mg
- Price$414.8
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146274
- Product descriptionBKM120 (NVP-BKM120, Buparlisib) >98%
- Packaging250mg
- Price$615.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146274
- Product descriptionBKM120 (NVP-BKM120, Buparlisib) >98%
- Packaging1g
- Price$1208.7
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD64903
- Product descriptionBKM 120
- Packaging10mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD64903
- Product descriptionBKM 120
- Packaging50mg
- Price$332.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number11587
- Product descriptionNVP-BKM120 ≥95%
- Packaging5mg
- Price$26
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11587
- Product descriptionNVP-BKM120 ≥95%
- Packaging1mg
- Price$31
- Updated2023-06-20
- Buy
- ManufacturerCayman Chemical
- Product number11587
- Product descriptionNVP-BKM120 ≥95%
- Packaging10mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11587
- Product descriptionNVP-BKM120 ≥95%
- Packaging25mg
- Price$102
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11587
- Product descriptionNVP-BKM120 ≥95%
- Packaging50mg
- Price$141
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM163600
- Product description5-(2,6-Dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine 98%
- Packaging250mg
- Price$224
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | SYN-1200-M001 | BKM120 ≥95% | 1mg | $65 | 2021-12-16 | Buy |
| ApexBio Technology | A3015 | BKM120 | 1unit | $28 | 2021-12-16 | Buy |
| ApexBio Technology | A3015 | BKM120 | 5mg | $90 | 2021-12-16 | Buy |
| Arctom | CFN60065 | Buparlisib(BKM120) ≥98% | 10mg | $218 | 2021-12-16 | Buy |
| Axon Medchem | Axon1797 | NVP-BKM120-BKM120|Buparlisib 98% | 2x25mg | $462 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146274 | BKM120 (NVP-BKM120, Buparlisib) >98% | 100mg | $414.8 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146274 | BKM120 (NVP-BKM120, Buparlisib) >98% | 250mg | $615.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146274 | BKM120 (NVP-BKM120, Buparlisib) >98% | 1g | $1208.7 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD64903 | BKM 120 | 10mg | $95 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD64903 | BKM 120 | 50mg | $332.5 | 2021-12-16 | Buy |
| Cayman Chemical | 11587 | NVP-BKM120 ≥95% | 5mg | $26 | 2024-03-01 | Buy |
| Cayman Chemical | 11587 | NVP-BKM120 ≥95% | 1mg | $31 | 2023-06-20 | Buy |
| Cayman Chemical | 11587 | NVP-BKM120 ≥95% | 10mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 11587 | NVP-BKM120 ≥95% | 25mg | $102 | 2024-03-01 | Buy |
| Cayman Chemical | 11587 | NVP-BKM120 ≥95% | 50mg | $141 | 2024-03-01 | Buy |
| Chemenu | CM163600 | 5-(2,6-Dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine 98% | 250mg | $224 | 2021-12-16 | Buy |
Properties
Melting point :143-147°C
Boiling point :645.7±65.0 °C(Predicted)
Density :1.382
storage temp. :-20°C
solubility :Soluble in DMSO (15 mg/ml)
form :White powder.
pka :5.94±0.50(Predicted)
color :White
Stability :Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Boiling point :645.7±65.0 °C(Predicted)
Density :1.382
storage temp. :-20°C
solubility :Soluble in DMSO (15 mg/ml)
form :White powder.
pka :5.94±0.50(Predicted)
color :White
Stability :Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Description
Phosphatidylinositol 3-kinases (PI3K) belong to a family of lipid kinases that is involved in many types of cancer. NVP-BKM120 is an orally bioavailable inhibitor of class I PI3K isoforms, potently blocking, in vitro, both p110α (IC50 = 52 nM) and p110β (IC50 = 166 nM). It much less effectively inhibits the class III PI3K Vps34 and mammalian target of rapamycin and has no effect on PI4Kβ and several other kinases. NVP-BKM120 prevents the growth of assorted cancer cell lines when used at 5 μM and inhibits tumor growth in vivo. It can be particularly effective against certain types of cancer when combined with other modulators.Related product price
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