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ChemicalBook >> CAS DataBase List >> AL-8810

AL-8810

AL-8810 price.
  • $105 - $2084
  • Product name: AL-8810
  • CAS: 246246-19-5
  • MF: C24H31FO4
  • MW: 402.5
  • EINECS:
  • MDL Number:MFCD04039992
  • Synonyms:AL 8810;9ALPHA,15R-DIHYDROXY-11BETA-FLUORO-15-(2,3-DIHYDRO-1H-INDEN-2-YL)-16,17,18, 19,20-PENTANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID;(5Z,13E)-(9S,11S,15R)-9,15,DIHYDROXY-11-FLUORO-15-(2-INDANYL)-16,17,18,19,20,PENTANOR-5,13-PROSTADIENOIC ACID;[1R-[1ALPHA(Z),2BETA(1E,3S*),3BETA,5ALPHA]]-7-[3-FLUORO-5-HYDROXY-2-[3-HYDROXY-4-[2-(2,3-DIHYDRO-1H-INDENYL)]-1-BUTENYL]CYCLOLPENTYL]-5-HEPTENOIC ACID;(5z, 13e)-(9s,11s,15r)-9,15,dihydroxy-11-fluoro-15-(2-indanyl)-16,17,18,19,20,pentanor-5,13-prostadienoic acid;[1R-[1α(Z),2β(1E,3S*),3β,5α]]-7-[3-Fluoro-5-hydroxy-2-[3-hydroxy-4-[2-(2,3-dihydro-1H-indenyl)]-1-butenyl]cyclolpentyl]-5-heptenoic acid, (5Z, 13E)-(9S,11S,15R)-9,15,Dihydroxy-11-fluoro-15-(2-indanyl)-16,17,18,19,20,pentanor-5,13-prostadienoic acid;[1R-[1α(Z),2β(1E,3S*),3β,5α]]-7-[3-Fluoro-5-hydroxy-2-[3-hydroxy-4-[2-(2,3-dihydro-1H-indenyl)]-1-butenyl]cyclolpentyl]-5-heptenoic acid;WTYSXBKKVNOOIX-JTGCGUAKSA-N
12 prices
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  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • Sigma-Aldrich
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerAK Scientific
  • Product number9156CN
  • Product descriptionAL-8810
  • Packaging1mg
  • Price$213
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number9156CN
  • Product descriptionAL-8810
  • Packaging10mg
  • Price$1007
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number9156CN
  • Product descriptionAL-8810
  • Packaging25mg
  • Price$2084
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4575
  • Product descriptionAL8810
  • Packaging1mg
  • Price$117
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4575
  • Product descriptionAL8810
  • Packaging5mg
  • Price$524
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4575
  • Product descriptionAL8810
  • Packaging10mg
  • Price$931
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4575
  • Product descriptionAL8810
  • Packaging25mg
  • Price$2037
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16735
  • Product descriptionAL 8810 ≥98%
  • Packaging1mg
  • Price$105
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16735
  • Product descriptionAL 8810 ≥98%
  • Packaging5mg
  • Price$459
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16735
  • Product descriptionAL 8810 ≥98%
  • Packaging10mg
  • Price$816
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16735
  • Product descriptionAL 8810 ≥98%
  • Packaging25mg
  • Price$1783
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberA3846
  • Product descriptionAL-8810 ≥98% (HPLC), solid
  • Packaging5mg
  • Price$548
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9156CN AL-8810 1mg $213 2021-12-16 Buy
AK Scientific 9156CN AL-8810 10mg $1007 2021-12-16 Buy
AK Scientific 9156CN AL-8810 25mg $2084 2021-12-16 Buy
ApexBio Technology B4575 AL8810 1mg $117 2021-12-16 Buy
ApexBio Technology B4575 AL8810 5mg $524 2021-12-16 Buy
ApexBio Technology B4575 AL8810 10mg $931 2021-12-16 Buy
ApexBio Technology B4575 AL8810 25mg $2037 2021-12-16 Buy
Cayman Chemical 16735 AL 8810 ≥98% 1mg $105 2024-03-01 Buy
Cayman Chemical 16735 AL 8810 ≥98% 5mg $459 2024-03-01 Buy
Cayman Chemical 16735 AL 8810 ≥98% 10mg $816 2024-03-01 Buy
Cayman Chemical 16735 AL 8810 ≥98% 25mg $1783 2024-03-01 Buy
Sigma-Aldrich A3846 AL-8810 ≥98% (HPLC), solid 5mg $548 2024-03-01 Buy

Properties

Boiling point :594.6±50.0 °C(Predicted)
Density :1.21±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 10 mg/mL, soluble
form :solid
pka :4.76±0.10(Predicted)
color :white to off-white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

AL 8810 is an 11β-fluoro analog of PGF2α which acts as a potent and selective antagonist at the FP receptor. AL 8810 has weak intrinsic agonist activity on FP receptor preparations in the 200-300 nM range, yet it fully antagonizes the activity of the potent FP receptor agonist fluprostenol at this concentration, with EC50 values of approximately 430 nM. AL 8810 fully antagonized the bimatoprost-induced calcium mobilization in Swiss 3T3 fibroblasts at 100 μM, indicating that bimatoprost acts as an FP agonist in this preparation. The Ki for the inhibition of several potent agonists at the cloned human ciliary body FP receptor is in the range of 1-2 μM.

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