Ranolazine dihydrochloride
- $19 - $945.95
- Product name: Ranolazine dihydrochloride
- CAS: 95635-56-6
- MF: C24H35Cl2N3O4
- MW: 500.46
- EINECS:
- MDL Number:MFCD03788770
- Synonyms:(+/-)-4-[2-HYDROXY-3-(O-METHOXYPHENOXY)PROPYL]-1-PIPERAZINEACETO-2',6'-XYLIDIDE DIHYDROCHLORIDE;n-(2,6-dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl]acetamide dihydrochloride;(+/-)-N-(2,6-DIMETHYLPHENYL)-4-[2-HYDROXY-3-(2-METHOXYPHENOXY)PROPYL]-1-PIPERAZINEACETAMIDE DIHYDROCHLORIDE;RANOLAZINE DIHYDROCHLORIDE;RANOLAZINE HCL;Ranolazine DiHCI ;Ranolazine and salt;N-(2,6-Dimethylphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)-propyl)piperazin-1-yl)acetamide di
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Brand
- AHH
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- AvaChem
- Cayman Chemical
- Chem-Impex
- ChemScene
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 50MG
- 0.1g
- 200mg
- 500mg
- 10mg
- 100mg
- 250mg
- 50
- 1g
- 5g
- 10mM(in 1mL DMSO)
- ManufacturerAHH
- Product numberAPI-1614
- Product descriptionRanolazine Dihydrochloride 98%
- Packaging1g
- Price$360
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberR463
- Product descriptionRanolazine Dihydrochloride
- Packaging1g
- Price$229
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA730331
- Product descriptionN-(2,6-Dimethylphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)acetamidedihydrochloride 98%
- Packaging100mg
- Price$19
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA730331
- Product descriptionN-(2,6-Dimethylphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)acetamidedihydrochloride 98%
- Packaging250mg
- Price$29
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA730331
- Product descriptionN-(2,6-Dimethylphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)acetamidedihydrochloride 98%
- Packaging1g
- Price$73
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA730331
- Product descriptionN-(2,6-Dimethylphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)acetamidedihydrochloride 98%
- Packaging5g
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004041
- Product descriptionRANOLAZINE DIHYDROCHLORIDE 95.00%
- Packaging1G
- Price$945.95
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004041
- Product descriptionRANOLAZINE DIHYDROCHLORIDE 95.00%
- Packaging50MG
- Price$184.8
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5300
- Product descriptionRanolazine2HCl
- Packaging10mg
- Price$44
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5300
- Product descriptionRanolazine2HCl
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5300
- Product descriptionRanolazine2HCl
- Packaging100mg
- Price$53
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5300
- Product descriptionRanolazine2HCl
- Packaging200mg
- Price$88
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2451
- Product descriptionRanolazine Dihydrochloride
- Packaging100mg
- Price$35
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15604
- Product descriptionRanolazine (hydrochloride) ≥98%
- Packaging50mg
- Price$81
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15604
- Product descriptionRanolazine (hydrochloride) ≥98%
- Packaging100mg
- Price$137
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15604
- Product descriptionRanolazine (hydrochloride) ≥98%
- Packaging250mg
- Price$298
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AHH | API-1614 | Ranolazine Dihydrochloride 98% | 1g | $360 | 2021-12-16 | Buy |
AK Scientific | R463 | Ranolazine Dihydrochloride | 1g | $229 | 2021-12-16 | Buy |
Ambeed | A730331 | N-(2,6-Dimethylphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)acetamidedihydrochloride 98% | 100mg | $19 | 2021-12-16 | Buy |
Ambeed | A730331 | N-(2,6-Dimethylphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)acetamidedihydrochloride 98% | 250mg | $29 | 2021-12-16 | Buy |
Ambeed | A730331 | N-(2,6-Dimethylphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)acetamidedihydrochloride 98% | 1g | $73 | 2021-12-16 | Buy |
Ambeed | A730331 | N-(2,6-Dimethylphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)acetamidedihydrochloride 98% | 5g | $250 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0004041 | RANOLAZINE DIHYDROCHLORIDE 95.00% | 1G | $945.95 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0004041 | RANOLAZINE DIHYDROCHLORIDE 95.00% | 50MG | $184.8 | 2021-12-16 | Buy |
ApexBio Technology | A5300 | Ranolazine2HCl | 10mg | $44 | 2021-12-16 | Buy |
ApexBio Technology | A5300 | Ranolazine2HCl | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
ApexBio Technology | A5300 | Ranolazine2HCl | 100mg | $53 | 2021-12-16 | Buy |
ApexBio Technology | A5300 | Ranolazine2HCl | 200mg | $88 | 2021-12-16 | Buy |
AvaChem | 2451 | Ranolazine Dihydrochloride | 100mg | $35 | 2021-12-16 | Buy |
Cayman Chemical | 15604 | Ranolazine (hydrochloride) ≥98% | 50mg | $81 | 2024-03-01 | Buy |
Cayman Chemical | 15604 | Ranolazine (hydrochloride) ≥98% | 100mg | $137 | 2024-03-01 | Buy |
Cayman Chemical | 15604 | Ranolazine (hydrochloride) ≥98% | 250mg | $298 | 2024-03-01 | Buy |
Properties
Melting point :222-229.5 °C(lit.)
storage temp. :Desiccate at RT
solubility :H2O: 10 mg/mL, soluble
form :solid
color :off-white
Merck :14,8111
Stability :Hygroscopic
CAS DataBase Reference :95635-56-6(CAS DataBase Reference)
storage temp. :Desiccate at RT
solubility :H2O: 10 mg/mL, soluble
form :solid
color :off-white
Merck :14,8111
Stability :Hygroscopic
CAS DataBase Reference :95635-56-6(CAS DataBase Reference)
Safety Information
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Signal word: | Warning | |||||||||||||||||||||
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Description
Ranolazine was developed to protect the heart from transient ischemia, as may occur during angina and infarct. It has diverse effects at the cellular level, inhibiting late sodium and potassium currents (IC50s = 3.9-16.6 μM for both) and blocking ligand binding to α1, β1, and β2 adrenergic receptors (Kis = 0.5-19.5 μM for all). Ranolazine inhibits fatty acid β-oxidation leading to decreased acetyl CoA, activation of pyruvate dehydrogenase, and increased glucose oxidation. It also weakly inhibits mitochondrial respiratory complex I.More related product prices
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