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ChemicalBook >> CAS DataBase List >> 1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate

1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate

1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate price.
  • $23.3 - $3544
  • Product name: 1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate
  • CAS: 203866-14-2
  • MF: C10H16FNO4
  • MW: 233.24
  • EINECS:
  • MDL Number:MFCD06796085
  • Synonyms:N-T-BOC-TRANS-4-FLUORO-L-PROLINE;N-(TERT-BUTOXYCARBONYL)-(2S,4R)-4-FLUOROPROLINE;BOC-TRANS-4-FLUORO-L-PROLINE;(2S,4R)-N-Boc-trans-4-Fluoro-L-Proline;(2S,4R)-4-Fluoropyrrolidine-2-carboxylic acid, N4-BOC protected;trans-4-Fluoro-L-proline, N-BOC protected;(2S,4R)-Boc-4-fluoro-pyrrolidine-2-carboxylic acid;(2R,4S)-N-BOC-4-FLUORO-D-PROLINE
37 prices
Selected condition：
Brand
  • ACHEMBLOCK
  • Acrotein
  • AK Scientific
  • Alfa Aesar
  • Alichem
  • American Custom Chemicals Corporation
  • Apolloscientific
  • Biosynth Carbosynth
  • Chemenu
  • Chem-Impex
  • ChemScene
  • Crysdot
  • Frontier Specialty Chemicals
  • Iris Biotech GmbH
  • Matrix Scientific
  • Sigma-Aldrich
  • SynQuest Laboratories
  • TCI Chemical
  • Usbiological
Package
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • 2g
  • 5G
  • 10g
  • 25g
  • 50g
  • 1kg
  • ManufacturerACHEMBLOCK
  • Product numberI-9223
  • Product description(2S,4R)-1-Boc-4-fluoropyrrolidine-2-carboxylicacid 97%
  • Packaging5G
  • Price$115
  • Updated2021-12-16
  • Buy
  • ManufacturerAcrotein
  • Product numberA-3257
  • Product descriptionN-Boc-trans-4-fluoro-L-proline 97%
  • Packaging5g
  • Price$314.6
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ97217
  • Product descriptionN-Boc-trans-4-fluoro-L-proline
  • Packaging1g
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberH27721
  • Product descriptionN-Boc-trans-4-fluoro-L-proline, 98%
  • Packaging250mg
  • Price$71.8
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberH27721
  • Product descriptionN-Boc-trans-4-fluoro-L-proline, 98%
  • Packaging1g
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number203866142
  • Product description(2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoropyrrolidine-2-carboxylicacid
  • Packaging5g
  • Price$315.01
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number203866142
  • Product description(2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoropyrrolidine-2-carboxylicacid
  • Packaging10g
  • Price$454.65
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number203866142
  • Product description(2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoropyrrolidine-2-carboxylicacid
  • Packaging1kg
  • Price$3544
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAAA0001693
  • Product descriptionN-BOC-TRANS-4-FLUORO-L-PROLINE 95.00%
  • Packaging1G
  • Price$376.95
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAAA0001693
  • Product descriptionN-BOC-TRANS-4-FLUORO-L-PROLINE 95.00%
  • Packaging5G
  • Price$1397.55
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC2200
  • Product description(2S,4R)-4-Fluoropyrrolidine-2-carboxylicacid,N-BOCprotected 95%
  • Packaging1g
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC2200
  • Product description(2S,4R)-4-Fluoropyrrolidine-2-carboxylicacid,N-BOCprotected 95%
  • Packaging5g
  • Price$82
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC2200
  • Product description(2S,4R)-4-Fluoropyrrolidine-2-carboxylicacid,N-BOCprotected 95%
  • Packaging10g
  • Price$136
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB50548
  • Product descriptionBoc-trans-4-fluoro-L-proline
  • Packaging2g
  • Price$60
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFB50548
  • Product descriptionBoc-trans-4-fluoro-L-proline
  • Packaging5G
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB50548
  • Product descriptionBoc-trans-4-fluoro-L-proline
  • Packaging10g
  • Price$150
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ACHEMBLOCK I-9223 (2S,4R)-1-Boc-4-fluoropyrrolidine-2-carboxylicacid 97% 5G $115 2021-12-16 Buy
Acrotein A-3257 N-Boc-trans-4-fluoro-L-proline 97% 5g $314.6 2021-12-16 Buy
AK Scientific J97217 N-Boc-trans-4-fluoro-L-proline 1g $25 2021-12-16 Buy
Alfa Aesar H27721 N-Boc-trans-4-fluoro-L-proline, 98% 250mg $71.8 2021-12-16 Buy
Alfa Aesar H27721 N-Boc-trans-4-fluoro-L-proline, 98% 1g $180 2021-12-16 Buy
Alichem 203866142 (2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoropyrrolidine-2-carboxylicacid 5g $315.01 2021-12-16 Buy
Alichem 203866142 (2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoropyrrolidine-2-carboxylicacid 10g $454.65 2021-12-16 Buy
Alichem 203866142 (2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoropyrrolidine-2-carboxylicacid 1kg $3544 2021-12-16 Buy
American Custom Chemicals Corporation AAA0001693 N-BOC-TRANS-4-FLUORO-L-PROLINE 95.00% 1G $376.95 2021-12-16 Buy
American Custom Chemicals Corporation AAA0001693 N-BOC-TRANS-4-FLUORO-L-PROLINE 95.00% 5G $1397.55 2021-12-16 Buy
Apolloscientific PC2200 (2S,4R)-4-Fluoropyrrolidine-2-carboxylicacid,N-BOCprotected 95% 1g $28 2021-12-16 Buy
Apolloscientific PC2200 (2S,4R)-4-Fluoropyrrolidine-2-carboxylicacid,N-BOCprotected 95% 5g $82 2021-12-16 Buy
Apolloscientific PC2200 (2S,4R)-4-Fluoropyrrolidine-2-carboxylicacid,N-BOCprotected 95% 10g $136 2021-12-16 Buy
Biosynth Carbosynth FB50548 Boc-trans-4-fluoro-L-proline 2g $60 2021-12-16 Buy
Biosynth Carbosynth FB50548 Boc-trans-4-fluoro-L-proline 5G $100 2021-12-16 Buy
Biosynth Carbosynth FB50548 Boc-trans-4-fluoro-L-proline 10g $150 2021-12-16 Buy

Properties

Melting point :115-119°C
Boiling point :346.0±42.0 °C(Predicted)
Density :1.24±0.1 g/cm3(Predicted)
refractive index :-69 ° (C=1, MeOH)
storage temp. :Inert atmosphere,Room Temperature
solubility :soluble in Methanol
form :powder to crystal
pka :3.53±0.40(Predicted)
color :White to Almost white
optical activity :[α]22/D -65.0±5°, c = 1 in chloroform
InChIKey :YGWZXQOYEBWUTH-RQJHMYQMSA-N
CAS DataBase Reference :203866-14-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

N-Boc-trans-4-fluoro-L-proline is a useful synthetic intermediate. It is used to prepare potent 3- or 4-substituted-2-cyanopyrrolidine dipeptidyl peptidase IV inhibitors. It is also used to synthesize pyrrolotriazines derivatives as pan-Aurora kinase inhibitors and anti-tumor agents.