4-(2-(5-Chloro-2-methoxybenzamido)ethyl)benzenesulfamide
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- $18 - $1960
- Product name: 4-(2-(5-Chloro-2-methoxybenzamido)ethyl)benzenesulfamide
- CAS: 16673-34-0
- MF: C16H17ClN2O4S
- MW: 368.84
- EINECS:240-722-5
- MDL Number:MFCD00193756
- Synonyms:4-(2-(5-Chloro-2-methoxybenzamido)ethyl)benzenesulfamide ;Glyburide Related Compound A (25 mg) (5-chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide);4-[2-(2-Methoxy-5-chlorobenzene-1-carboxaMido)ethyl]benzenesulfonaMide;5-Chloro-N-(p-sulfaMoylphenethyl)-o-anisaMide;GlibenclaMide (Glyburide) IMpurity A;Glyburide Related CoMpound A;Glyburide Related Compound A (25 mg) (4-[2-(5-chloro-2-methoxybenzamido)ethyl]benzenesulfonamide);Glyburide USP RC A
26 prices
Selected condition：
Brand
- AHH
- AK Scientific
- Alichem
- Ambeed
- AvaChem
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TRC
Package
- 10mg
- 25MG
- 50mg
- 100mg
- 1g
- g0325010
- 250mg
- 5g
- 10g
- 25g
- 500g
- ManufacturerAHH
- Product numberMT-05659
- Product description4-[2-(5-Chloro-2-methoxybenzamido)ethyl]phenylsulphonamide 95%
- Packaging500g
- Price$475
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5142
- Product descriptionNLRP3InflammasomeInhibitorI
- Packaging10mg
- Price$145
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number16673340
- Product description5-Chloro-2-methoxy-N-(4-sulfamoylphenethyl)benzamide
- Packaging10g
- Price$1122.11
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number16673340
- Product description5-Chloro-2-methoxy-N-(4-sulfamoylphenethyl)benzamide
- Packaging25g
- Price$1960
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA118776
- Product description5-Chloro-2-methoxy-N-(4-sulfamoylphenethyl)benzamide 98+%
- Packaging1g
- Price$18
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA118776
- Product description5-Chloro-2-methoxy-N-(4-sulfamoylphenethyl)benzamide 98+%
- Packaging5g
- Price$49
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA118776
- Product description5-Chloro-2-methoxy-N-(4-sulfamoylphenethyl)benzamide 98+%
- Packaging25g
- Price$214
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3740
- Product description5-Chloro-2-methoxy-N-[2-(4-sulphamoylphenyl)ethyl]benzamide
- Packaging10mg
- Price$39
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3740
- Product description5-Chloro-2-methoxy-N-[2-(4-sulphamoylphenyl)ethyl]benzamide
- Packaging100mg
- Price$139
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC155783
- Product descriptionNLRP3i
- Packaging10mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC155783
- Product descriptionNLRP3i
- Packaging50mg
- Price$262.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number30895
- Product descriptionNLRP3i
- Packaging1g
- Price$62
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-W011798
- Product descriptionNLRP3-IN-2 98.52%
- Packaging5g
- Price$88
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-W011798
- Product descriptionNLRP3-IN-2 98.52%
- Packaging10g
- Price$172
- Updated2021-12-16
- Buy
- ManufacturerCSNpharm
- Product numberCSN21903
- Product descriptionNLRP3i
- Packaging100mg
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC26132
- Product descriptionNLRP3InflammasomeInhibitorI >98%
- Packaging100mg
- Price$200
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | MT-05659 | 4-[2-(5-Chloro-2-methoxybenzamido)ethyl]phenylsulphonamide 95% | 500g | $475 | 2021-12-16 | Buy |
| AK Scientific | SYN5142 | NLRP3InflammasomeInhibitorI | 10mg | $145 | 2021-12-16 | Buy |
| Alichem | 16673340 | 5-Chloro-2-methoxy-N-(4-sulfamoylphenethyl)benzamide | 10g | $1122.11 | 2021-12-16 | Buy |
| Alichem | 16673340 | 5-Chloro-2-methoxy-N-(4-sulfamoylphenethyl)benzamide | 25g | $1960 | 2021-12-16 | Buy |
| Ambeed | A118776 | 5-Chloro-2-methoxy-N-(4-sulfamoylphenethyl)benzamide 98+% | 1g | $18 | 2021-12-16 | Buy |
| Ambeed | A118776 | 5-Chloro-2-methoxy-N-(4-sulfamoylphenethyl)benzamide 98+% | 5g | $49 | 2021-12-16 | Buy |
| Ambeed | A118776 | 5-Chloro-2-methoxy-N-(4-sulfamoylphenethyl)benzamide 98+% | 25g | $214 | 2021-12-16 | Buy |
| AvaChem | 3740 | 5-Chloro-2-methoxy-N-[2-(4-sulphamoylphenyl)ethyl]benzamide | 10mg | $39 | 2021-12-16 | Buy |
| AvaChem | 3740 | 5-Chloro-2-methoxy-N-[2-(4-sulphamoylphenyl)ethyl]benzamide | 100mg | $139 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC155783 | NLRP3i | 10mg | $75 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC155783 | NLRP3i | 50mg | $262.5 | 2021-12-16 | Buy |
| Cayman Chemical | 30895 | NLRP3i | 1g | $62 | 2024-03-01 | Buy |
| ChemScene | CS-W011798 | NLRP3-IN-2 98.52% | 5g | $88 | 2021-12-16 | Buy |
| ChemScene | CS-W011798 | NLRP3-IN-2 98.52% | 10g | $172 | 2021-12-16 | Buy |
| CSNpharm | CSN21903 | NLRP3i | 100mg | $45 | 2021-12-16 | Buy |
| DC Chemicals | DC26132 | NLRP3InflammasomeInhibitorI >98% | 100mg | $200 | 2021-12-16 | Buy |
Properties
Melting point :209-214 °C
Density :1.356±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 45 mg/ml).
form :Solid
pka :10.14±0.10(Predicted)
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChI :InChI=1S/C16H17ClN2O4S/c1-23-15-7-4-12(17)10-14(15)16(20)19-9-8-11-2-5-13(6-3-11)24(18,21)22/h2-7,10H,8-9H2,1H3,(H,19,20)(H2,18,21,22)
InChIKey :KVWWTCSJLGHLRM-UHFFFAOYSA-N
SMILES :C(NCCC1=CC=C(S(N)(=O)=O)C=C1)(=O)C1=CC(Cl)=CC=C1OC
CAS DataBase Reference :16673-34-0(CAS DataBase Reference)
Density :1.356±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 45 mg/ml).
form :Solid
pka :10.14±0.10(Predicted)
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChI :InChI=1S/C16H17ClN2O4S/c1-23-15-7-4-12(17)10-14(15)16(20)19-9-8-11-2-5-13(6-3-11)24(18,21)22/h2-7,10H,8-9H2,1H3,(H,19,20)(H2,18,21,22)
InChIKey :KVWWTCSJLGHLRM-UHFFFAOYSA-N
SMILES :C(NCCC1=CC=C(S(N)(=O)=O)C=C1)(=O)C1=CC(Cl)=CC=C1OC
CAS DataBase Reference :16673-34-0(CAS DataBase Reference)
Safety Information
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Description
NLRP3i (16673-34-0) is an NLRP3 inflammasome inhibitor which likely acts via interfering with the formation of the NLRP3 inflammasome complex and which exhibits promising?in vivo?protective activities in mouse acute myocardial infarction models. It blocks ASC aggregation, blocks the release of IL-1β and the activation of caspase-1 in macrophages expressing constitutively active NLRP3 but does not directly inhibit caspase-1.1,2?Limits infarct size after myocardial ischemia-reperfusion as well as leukocyte infiltration in a peritonitis model in mice.2Related product price
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