Nitroguanidine
Product identifier
- Product name: Nitroguanidine
- CBnumber: CB1853823
- CAS: 556-88-7
- EINECS Number: 209-143-5
- Synonyms: Nitroguanidine,Picrite
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
Classification of the substance or mixture
Explosives, Division 1.1
Label elements
Pictogram(s)
-
Signal word
Danger
H201 Explosive; mass explosion hazard
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P230 Keep wetted with ...
P234 Keep only in original packaging.
P240 Ground and bond container and receiving equipment.
P250 Do not subject to grinding/shock/friction/….
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P370+P372+P380+P373 In case of fire: Explosion risk. Evacuate area. DO NOT fight fire when fire reaches explosives.
P401 Store in accordance with…
P503 Refer to manufacturer/supplier… for information on disposal/recovery/recycling.
Other hazards
no data available
Substance
- Product name: Nitroguanidine
- Synonyms: Nitroguanidine,Picrite
- CAS: 556-88-7
- EC number: 209-143-5
- MF: CH4N4O2
- MW: 104.07
Description of first aid measures
If inhaledMove the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.
Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.
Rinse with pure water for at least 15 minutes. Consult a doctor.
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
Most important symptoms and effects, both acute and delayed
Excerpt from ERG Guide 113 [Flammable Solids - Toxic (Wet/Desensitized Explosive)]: Some are toxic and may be fatal if inhaled, swallowed or absorbed through skin. Contact may cause burns to skin and eyes. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may cause pollution. (ERG, 2016)
Excerpt from ERG Guide 112 [Explosives* - Division 1.1, 1.2, 1.3 or 1.5]: Fire may produce irritating, corrosive and/or toxic gases. (ERG, 2016)
Indication of any immediate medical attention and special treatment needed
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Dinitrophenol and Related Compounds
Extinguishing media
If material on fire or involved in fire: Dangerously explosive. Do not fight fires in a cargo of explosives. Evacuate area and let burn. Nitroguanidine, dry
Specific Hazards Arising from the Chemical
Excerpt from ERG Guide 113 [Flammable Solids - Toxic (Wet/Desensitized Explosive)]: Flammable/combustible material. May be ignited by heat, sparks or flames. DRIED OUT material may explode if exposed to heat, flame, friction or shock; treat as an explosive, refer to ERG Guide 112. Keep material wet with water or treat as an explosive, refer to ERG Guide 112. Runoff to sewer may create fire or explosion hazard. (ERG, 2016)
Excerpt from ERG Guide 112 [Explosives* - Division 1.1, 1.2, 1.3 or 1.5]: MAY EXPLODE AND THROW FRAGMENTS 1600 METERS (1 MILE) OR MORE IF FIRE REACHES CARGO. For information on "Compatibility Group" letters, refer to Glossary section. (ERG, 2016)
Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
NFPA 704
| HEALTH | 2 | Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine) | |
| FIRE | 0 | Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand. Materials that will not burn in air when exposed to a temperature of 820 °C (1,500 °F) for a period of 5 minutes.(e.g. Carbon tetrachloride) | |
| REACT | 4 | Readily capable of detonation or explosive decomposition at normal temperatures and pressures (e.g. nitroglycerin,chlorine dioxide, nitrogen triiodide) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.
Environmental precautions
Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up
Use personal protective equipment. Avoid dust formation. Avoid breathing dust. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations. Keep in suitable, closed containers for disposal.
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Keep container tightly closed in a dry and well-ventilated place. Store in cool place. Keep in a dry place. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed. Keep away from sources of ignition - No smoking. Take measures to prevent the build up of electrostatic charge.
Control parameters
Occupational Exposure limit valuesno data available
no data available
Exposure controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures
Eye/face protectionWear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).
Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.
no data available
Information on basic physicochemical properties
- Physical state
Solid. Crystalline.
- Colour
Colorless.
- Odour
no data available
- Melting point/freezing point
Remarks:Source: Kenyon 1982.
- Boiling point or initial boiling point and boiling range
323.3°C at 760 mmHg
- Flammability
no data available
- Lower and upper explosion limit/flammability limit
no data available
- Flash point
149.3°C
- Auto-ignition temperature
Ca. 216 °C.
- Decomposition temperature
no data available
- pH
no data available
- Kinematic viscosity
no data available
- Solubility
Slightly soluble in ethanol; insoluble in ethyl ether; very soluble in alkali
- Partition coefficient n-octanol/water
log Pow = Ca. -0.815. Temperature:20 °C.
- Vapour pressure
0 Pa. Temperature:20 °C. Remarks:Result is derived using the Clausius-Clapeyron equation.
- Density and/or relative density
1.76 g/cm3. Temperature:20 °C.;1.76. Temperature:20 °C.
- Relative vapour density
no data available
- Particle characteristics
no data available
Reactivity
No rapid reaction with air. No rapid reaction with water.
Chemical stability
Alpha is the usual stable form...
Possibility of hazardous reactions
A very dangerous fire hazard when exposed to heat, flame, or by chemical reaction with oxidizers.Nitroalkanes, such as NITROGUANIDINE, range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction that culminates in a detonation. Nitroalkanes are milder oxidizing agents, but still react violently with reducing agents at higher temperature and pressures. Nitroalkanes react with inorganic bases to form explosive salts. The presence of metal oxides increases the thermal sensitivity of nitroalkanes. Nitroalkanes with more than one nitro group are generally explosive. Nitroalkanes are insoluble in water. Flammable/combustible material. May be ignited by heat, sparks or flames. DRIED OUT material may explode if exposed to heat, flame, friction or shock; Treat as an explosive. Mercury and silver complex salts of nitroguanidine are very impact sensitive.
Conditions to avoid
no data available
Incompatible materials
Can react vigorously with oxidizing materials and the derivatives can be explosive.
Hazardous decomposition products
Decomposes immediately on melting to form ammonia, water vapor, and solid products. The gases from the decomposition of nitroguanidine are far less erplosive than gases from other similar explosives.
Acute toxicity
- Oral: LD50 Rat oral 10,200 mg/kg
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
CLASSIFICATION: D; not classifiable as to human carcinogenicity. BASIS FOR CLASSIFICATION: Pertinent data regarding carcinogenicity have not been located in the available literature. HUMAN CARCINOGENICITY DATA: None. ANIMAL CARCINOGENICITY DATA: None. Based on former classification system
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
Toxicity
- Toxicity to fish: LC50 - Poecilia reticulata - > 1 600 mg/L - 96 h. Remarks:80% active ingredient.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - > 3 000 mg/L - 48 h. Remarks:80% active ingredient, 20% water.
- Toxicity to algae: EC50 - Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum) - ca. 2 000 mg/L - 5 d.
- Toxicity to microorganisms: EC50 - activated sludge of a predominantly domestic sewage - > 300 mg/L - 3 h. Remarks:Respiration rate.
Persistence and degradability
AEROBIC: 1-Nitroguanidine is not susceptible to aerobic biodegradation in activated sludge, and was stable under sterile reducing conditions(1,2). No decomposition occurred under aerobic conditions in either batch or continuous cultures(2). After acclimation, nitroguanidine co-metabolizes to form nitrosoguanidine(2). 1-Nitroguanidine, present at 100 mg/L, reached less than 14% of its theoretical BOD after 4 weeks in an activated sludge inoculum at 30 mg/L in the Japanese MITI test(3).
Bioaccumulative potential
An estimated BCF of 3.2 was calculated in fish for 1-nitroguanidine(SRC), using a log Kow of -0.89(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
The Koc of 1-nitroguanidine is estimated as 21(SRC), using a log Kow of -0.89(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that 1-nitroguanidine is expected to have very high mobility in soil. A sorption partition coefficient of <0.1 was calculated using sediments characterized by high surface areas(4).
Other adverse effects
no data available
Disposal methods
ProductThe material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
UN Number
ADR/RID: UN1336 (For reference only, please check.)
IMDG: UN1336 (For reference only, please check.)
IATA: UN1336 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: NITROGUANIDINE (PICRITE), WETTED with not less than 20% water, by mass (For reference only, please check.)
IMDG: NITROGUANIDINE (PICRITE), WETTED with not less than 20% water, by mass (For reference only, please check.)
IATA: NITROGUANIDINE (PICRITE), WETTED with not less than 20% water, by mass (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 4.1 (For reference only, please check.)
IMDG: 4.1 (For reference only, please check.)
IATA: 4.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
Safety, health and environmental regulations specific for the product in question
European Inventory of Existing Commercial Chemical Substances (EINECS)Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.