天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

ChemicalBook >> journal list >> Bioelectrochemistry >>article
Bioelectrochemistry

Bioelectrochemistry

IF: 4.79
Download PDF

Selective aptasensor of deoxynivalenol based on dual signal enhancement of thionine electrochemistry using silver nanoparticle-loaded label at gold nanoparticle?…

Published:9 December 2024 DOI: 10.1016/j.bioelechem.2024.108881 PMID: 39657431
Xiaoying Cui,?Ke Zhao,?Zhengquan Qu,?Xipeng Chao,?Lingling Xie,?Hanyu Chen,?Baoshan He,?Baozhong Zhang

Abstract

In this work, an efficient sensing platform deoxynivalenol (DON) detection was constructed through monitoring the current change of a competitive mechanism triggered by DON, leading the signal label detached from the electrode surface by square-wave voltammetry using thionine (Thi) as a redox indicator. The complementary strand of aptamer (cDNA) and Thi were loaded onto Fe/Ni bimetallic metal-organic framework loaded with sliver nanoparticles (AgNPs@FeNi-MOF) to construct AgNPs@FeNi-MOF/cDNA/Thi signal probes. In the presence of DON, the aptamer sequence was more predisposed to form an aptamer-DON complex, resulting in the displacement of the cDNA. The signal probe was subsequently released, leading to a decrease in the signal intensity of Thi. Notably, AgNPs@FeNi-MOF has a larger electroactive specific surface area and is able to load more cDNA and thi, which can amplify the signal. Under the optimal experimental conditions, the developed sensor exhibits a good linear response in the range of 1?×?10-2 to 1?×?104 pg/mL, with a limit of detection (LOD) of 5.68?fg/mL and has good selectivity, reproducibility and stability.

Substances (4)

Materials
Procduct Name CAS Molecular Formula Supplier Price
Sodium hydroxide 1310-73-2 NaOH 1212 suppliers $14.00-$16472.00
Bovine albumin 9048-46-8 N/A 506 suppliers $15.00-$17060.00
AFLATOXIN B1 1162-65-8 C17H12O6 200 suppliers $46.00-$1625.00
DEOXYNIVALENOL 51481-10-8 C15H20O6 167 suppliers $49.00-$2704.00

Similar articles

IF:0

D-Glucose-Mediated Gold Nanoparticle Fabrication for Colorimetric Detection of Foodborne Pathogens

Biosensors Seo Yeon Park, Rajamanickam Sivakumar,etc Published: 1 June 2024
IF:0

Bioactivity of Mupirocin Nanoparticle-Loaded Hydrogel against Methicillin-Resistant Staphylococcus aureus (MRSA)

Applied microbiology Sukanjana Kamlungmak,?Monwadee Wonglapsuwan,etc Published: 3 March 2022