英文名稱:
4-[[6-amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3, 5 –dimethylbenzonitrile
CAS號:
269055-15-4
分子式:
C20H15BrN6O
分子量:
435.28
EINECS號:
682-331-6
熔點
.265°C (dec.)
沸點
637.4±65.0 °C(Predicted)
密度
1.439 g/cm3
儲存條件
-20°C Freezer
酸度系數(shù)(pKa)
1.23±0.10(Predicted)
Etravirine (TMC125), is highly active against wild-type HIV-1 with EC50 of 1.4 nM to 4.8 nM and shows some activity against HIV-2 with EC50 of 3.5 μM. TMC125 also inhibits a series of HIV-1 group M subtypes and circulating recombinant forms and a group O virus.
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