BAY 41-2272 NEW
| Price | $30 | $45 | $79 |
| Package | 2mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: BAY 41-2272 | CAS No.: 256376-24-6 |
| Purity: 99.54% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | BAY 41-2272 |
| Description | BAY 41-2272 is a direct and NO-independent soluble guanylate cyclase (sGC) stimulator. |
| In vitro | In vitro, BAY 41-2272 results in concentration dependent relaxation of human and rabbit cavernosum with EC50 of 489.1 nM and 406.3 nM, respectively. [3] |
| In vivo | In female spontaneously hypertensive rats, BAY 41-2272 (10 mg/kg, p.o.) shows antiplatelet effect, strongly decreases blood pressure and increases survival. [2] In C. albicans-infected mice, BAY 41-2272 (10 mg/kg, i.p.) markedly increases macrophage-dependent cell influx to the peritoneum in addition to macrophage functions, and reduces the death rate. [4] In db/db-/- type II diabetic and obese mice, BAY 41-2272 improves impaired corpus cavernosum (CC) relaxation. [5] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 36 mg/mL (100 mM) |
| Keywords | Inhibitor | BAY 41-2272 | inhibit | Guanylate Cyclase | BAY 41 2272 | BAY 412272 |
| Inhibitors Related | LY83583 | Lificiguat | Sinitrodil | Riociguat | Nelociguat | Nitroprusside disodium dihydrate | Vericiguat | ODQ | Methylene Blue | Methylene Blue trihydrate | BAY 41-8543 | Cinaciguat |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | NO PAINS Compound Library | Anti-Cardiovascular Disease Compound Library | Orally Active Compound Library | Bioactive Compounds Library Max | Preclinical Compound Library | GPCR Compound Library | Human Metabolite Library | Anti-Hypertension Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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