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Standard

In the analysis work, it often demanded to apply high-quality compound with the exact content being accurate in order to be compared as the detection control or used to calibrate the instrument, the compound is known as standard sample.
Standard refers to the standard substance used for measuring the potency of biological products. When the production department submits to a higher authority for approval of the quality standard of the biological product, they should also provide the standard sample (indicated in unit (μ)) used for measuring the potency of the tested product.

According to different application, the verification products can be divided into biological standard for the testing of biological products, endocrine drugs, antibiotics and other bioassay and chemical standards including:
1 chemical standards used for calibration of the instrument;
2 chemical reference standards used for calibration of the ultraviolet or infrared spectrum of the drugs;
3 control standards used for the purity test of drugs as well as the impurity control or as the control standards for content determination of the medicine.

In the page 67 of the appendix in the People's Republic of China Pharmacopoeia 1990 1st edition, we can find hundreds kinds of standards including bornyl ester acetate, eugenol and panaxadiol as well as 39 kinds of control medicine for the purify inspection of traditional Chinese medicine, impurity control or the content determination.

International standards
This refers to standard sample, with the potency units of the existing international standard sample potency units as baseline, undergoing further calibration of its potency units on the basis of a wide range of international cooperation. Its potency is expressed in 1U. For a certain product, for the establishment of the first international standard sample, the determination of its potency units should be consulted and decided by the Committee of Experts before the announcement. The international standard is a standard reference substance for worldwide preparation of national standards, so that the international standards can achieve unity.

Reagents and standards
All reagents in the food analysis laboratories should be clearly labeled to indicate the following: 1 name; 2 the date of preparation; 3 Signature from the people in charge; 4 if necessary, we need to add content such as safety and validity and so on.
Most food analysis should use standard sample as reference for qualitative and quantitative determination. The standard sample should be classified according to the following classification methods: 1 international standard; 2 national standards; 3 internal standard; 4 other standards.
Receptacle for reference standards should be clearly affixed to the label, to indicate the following: 1 name; 2 standard document number; 3 Opening times; 4 Validity; 5 Signature.
In addition, the laboratory should keep all the necessary specific files for all the necessary reference standards.
Capacity analysis standard solution should also be strictly managed. It should be clearly posted on all the standard solution containers with labels to indicate: 1 name; 2 concentration; 3 formulation date; 4 No of formulated procedures; 5 storage conditions; 6 validity; 7 Signature from people in charge.

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Structure Chemical Name CAS MF
2-Isopropylthioxanthone 2-Isopropylthioxanthone 5495-84-1 C16H14OS
alpha-(2,4-Dichlorophenyl)-1H-imidazole-1-ethanol alpha-(2,4-Dichlorophenyl)-1H-imidazole-1-ethanol 24155-42-8 C11H10Cl2N2O
Docosahexaenoic Acid Docosahexaenoic Acid 6217-54-5 C22H32O2
Ketamine hydrochloride Ketamine hydrochloride 1867-66-9 C13H16ClNO.ClH
Chloroauric acid Chloroauric acid 16903-35-8 AuCl4H
2-ACETAMIDO-5-NITROTHIAZOLE 2-ACETAMIDO-5-NITROTHIAZOLE 140-40-9 C5H5N3O3S
2,3-Dichlorotoluene 2,3-Dichlorotoluene 32768-54-0 C7H6Cl2
RONIDAZOLE RONIDAZOLE 7681-76-7 C6H8N4O4
m-Toluidine m-Toluidine 108-44-1 C7H9N
Linseed oil Linseed oil 8001-26-1
N-Methyl pyrrole N-Methyl pyrrole 96-54-8 C5H7N
N-Carbethoxy-4-piperidone N-Carbethoxy-4-piperidone 29976-53-2 C8H13NO3
N-desalkylflurazepam N-desalkylflurazepam 2886-65-9 C15H10ClFN2O
trans-4-Isopropylcyclohexane carboxylic acid trans-4-Isopropylcyclohexane carboxylic acid 7077-05-6 C10H18O2
Naphazoline nitrate Naphazoline nitrate 5144-52-5 C14H15N3O3
Rafoxanide Rafoxanide 22662-39-1 C19H11Cl2I2NO3
2'H-Androst-2-eno[3,2-c]pyrazol-5'(1'H)-one, 17-hydroxy-17-(methyl-d3)-, (5α,17β)- (9CI) 2'H-Androst-2-eno[3,2-c]pyrazol-5'(1'H)-one, 17-hydroxy-17-(methyl-d3)-, (5α,17β)- (9CI) 170082-17-4 C21H32N2O2
DL-10-CAMPHORSULFONIC ACID DL-10-CAMPHORSULFONIC ACID 5872-08-2 C10H16O4S
2-Butyl-3-(3,5-Diiodo-4-hydroxy benzoyl) benzofuran 2-Butyl-3-(3,5-Diiodo-4-hydroxy benzoyl) benzofuran 1951-26-4 C19H16I2O3
(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride (1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride 101152-94-7 C15H23ClN2O
Pleuromulin Pleuromulin 125-65-5 C22H34O5
2-Pyrrolidinone 2-Pyrrolidinone 616-45-5 C4H7NO
OUABAIN OCTAHYDRATE OUABAIN OCTAHYDRATE 11018-89-6 C29H60O20
Fosphenytoin sodium Fosphenytoin sodium 92134-98-0 C16H16N2NaO6P
4-Methylaminophenol sulfate 4-Methylaminophenol sulfate 55-55-0 C7H11NO5S
Pentachloroaniline Pentachloroaniline 527-20-8 C6H2Cl5N
1,4-BIS(2-METHYLSTYRYL)BENZENE 1,4-BIS(2-METHYLSTYRYL)BENZENE 13280-61-0 C24H22
Pyrene Pyrene 129-00-0 C16H10
Pentamidine isethionate Pentamidine isethionate 140-64-7 C23H36N4O10S2
Closantel sodium Closantel sodium 61438-64-0 C22H15Cl2I2N2NaO2
Benzidine Benzidine 92-87-5 C12H12N2
Sodium Phosphate Monobasic Monohydrate Sodium Phosphate Monobasic Monohydrate 10049-21-5 H4NaO5P
SAQUINAVIR MESYLATE SAQUINAVIR MESYLATE 149845-06-7 C39H54N6O8S
Tiagabine hydrochloride Tiagabine hydrochloride 145821-59-6 C20H26ClNO2S2
Methyl 2,4-dichlorophenylacetate Methyl 2,4-dichlorophenylacetate 55954-23-9 C9H8Cl2O2
GENITE GENITE 97-16-5 C12H8Cl2O3S
Norandrostenedione Norandrostenedione 734-32-7 C18H24O2
Fluorescein diacetate Fluorescein diacetate 596-09-8 C24H16O7
2-(Aminomethyl)-1-ethylpyrrolidine 2-(Aminomethyl)-1-ethylpyrrolidine 26116-12-1 C7H16N2
4-Oxo-TEMPO 4-Oxo-TEMPO 2896-70-0 C9H16NO2*
4,4'-DIAMINO-3,3'-DIMETHYLDIPHENYLMETHANE 4,4'-DIAMINO-3,3'-DIMETHYLDIPHENYLMETHANE 838-88-0 C15H18N2
Closantel Closantel 57808-65-8 C22H14Cl2I2N2O2
4-(2-PYRIDYLAZO)RESORCINOL MONOSODIUM SALT HYDRATE 4-(2-PYRIDYLAZO)RESORCINOL MONOSODIUM SALT HYDRATE 16593-81-0 C11H12N3NaO3
AFLATOXIN B1 AFLATOXIN B1 1162-65-8 C17H12O6
4-Hydroxy-2,2,6,6-tetramethyl-piperidinooxy 4-Hydroxy-2,2,6,6-tetramethyl-piperidinooxy 2226-96-2 C9H18NO2*
Articaine hydrochloride Articaine hydrochloride 23964-57-0 C13H20N2O3S.ClH
5-Hydroxytryptamine 5-Hydroxytryptamine 50-67-9 C10H12N2O
Flutrimazole Flutrimazole 119006-77-8 C22H16F2N2
Hydroxocobalamin Hydroxocobalamin 13422-51-0 C62H90ClCoN13O15P
Pachymic acid Pachymic acid 29070-92-6 C33H52O5
2-Methoxy-5-methylaniline 2-Methoxy-5-methylaniline 120-71-8 C8H11NO
Pregna-4,6-diene-3,20-dione Pregna-4,6-diene-3,20-dione 1162-56-7 C21H28O2
Cyclobenzaprine hydrochloride Cyclobenzaprine hydrochloride 6202-23-9 C20H22ClN
2-Aminobenzimidazole 2-Aminobenzimidazole 934-32-7 C7H7N3
Mefloquine hydrochloride Mefloquine hydrochloride 51773-92-3 C17H17ClF6N2O
CYCLOSPORIN D CYCLOSPORIN D 63775-96-2 C63H113N11O12
1-(4-Chlorobenzhydryl)piperazine 1-(4-Chlorobenzhydryl)piperazine 303-26-4 C17H19ClN2
Sultamicillin tosilate Sultamicillin tosilate 83105-70-8 C32H38N4O12S3
5-Nitro-2-furaldehyde diacetate 5-Nitro-2-furaldehyde diacetate 92-55-7 C9H9NO7
Decahydronaphthalene Decahydronaphthalene 91-17-8 C10H18
α-Ketoglutaric acid disodium salt α-Ketoglutaric acid disodium salt 305-72-6 C5H6O5.2Na
1,1-Dichloroethane 1,1-Dichloroethane 75-34-3 C2H4Cl2
NIOBIUM NIOBIUM 7440-03-1 Nb
AMMONIUM CERIUM(IV) SULFATE AMMONIUM CERIUM(IV) SULFATE 7637-03-8 CeH5NO4S
Triamcinolone diacetate Triamcinolone diacetate 67-78-7 C25H31FO8
1-ETHYL-7-CHLORO-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID 1-ETHYL-7-CHLORO-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID 68077-26-9 C12H9ClFNO3
Sulcotrione Sulcotrione 99105-77-8 C14H13ClO5S
1-Aminohydantoin hydrochloride 1-Aminohydantoin hydrochloride 2827-56-7 C3H6ClN3O2
2,4-Dibromophenol 2,4-Dibromophenol 615-58-7 C6H4Br2O
2-AMINO-3-CHLORO-1,4-NAPHTHOQUINONE 2-AMINO-3-CHLORO-1,4-NAPHTHOQUINONE 2797-51-5 C10H6ClNO2
3-Amino-1,2,4-Triazole 3-Amino-1,2,4-Triazole 61-82-5 C2H4N4
2-Chloro-4-nitrophenol 2-Chloro-4-nitrophenol 619-08-9 C6H4ClNO3
1,4-bis-2(5-phenyloxazoyl)benzene 1,4-bis-2(5-phenyloxazoyl)benzene 1806-34-4 C24H16N2O2
Tiamulin Tiamulin 55297-95-5 C28H47NO4S
PHOSPHATE STANDARD PHOSPHATE STANDARD 14265-44-2 O4P-3
Potassium phthalate (2:1) Potassium phthalate (2:1) 29801-94-3 C8H5KO4
2-Chloroadenine 2-Chloroadenine 1839-18-5 C5H4ClN5
DEOXYRIBONUCLEIC ACID DEOXYRIBONUCLEIC ACID 100403-24-5 Null
DIMETHYL POPOP DIMETHYL POPOP 3073-87-8 C26H20N2O2
Iminodibenzyl Iminodibenzyl 494-19-9 C14H13N
3,3'-Dichlorobenzidine dihydrochloride 3,3'-Dichlorobenzidine dihydrochloride 612-83-9 C12H11Cl3N2
Nitroxinil Nitroxinil 1689-89-0 C7H3IN2O3
2,4,6-TRIBROMOANISOLE 2,4,6-TRIBROMOANISOLE 607-99-8 C7H5Br3O
(S)-1,2,4-Butanetriol (S)-1,2,4-Butanetriol 42890-76-6 C4H10O3
Mirtazapine Mirtazapine 61337-67-5 C17H19N3
PROXYPHYLLINE PROXYPHYLLINE 603-00-9 C10H14N4O3
Retigabine Retigabine 150812-12-7 C16H18FN3O2
Ethylenebis(oxyethylenenitrilo)tetraacetic acid Ethylenebis(oxyethylenenitrilo)tetraacetic acid 67-42-5 C14H24N2O10
Zinkamalgam Zinkamalgam 52374-36-4 Zn
2-Ethylhexyl salicylate 2-Ethylhexyl salicylate 118-60-5 C15H22O3
Arachidonic acid Arachidonic acid 506-32-1 C20H32O2
Dibenzosuberone Dibenzosuberone 1210-35-1 C15H12O
Mebhydrolin napadisylate Mebhydrolin napadisylate 6153-33-9 C48H48N4O6S2
Propyzamide Propyzamide 23950-58-5 C12H11Cl2NO
Tryptamine Tryptamine 61-54-1 C10H12N2
Mehtyl 6-[3-(1-adamanty)-4-methoxy phenyl]-2-naphthoate Mehtyl 6-[3-(1-adamanty)-4-methoxy phenyl]-2-naphthoate 106685-41-0 C29H30O3
1,3-Dimethylamylamine 1,3-Dimethylamylamine 105-41-9 C7H17N
L(+)-Tartaric acid L(+)-Tartaric acid 87-69-4 C4H6O6
2,3-Dimethylaniline 2,3-Dimethylaniline 87-59-2 C8H11N
Cilastatin sodium Cilastatin sodium 81129-83-1 C16H25N2O5S.Na
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