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Eiwei?-Tyrosinkinase (PTK)

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Structure Chemical Name CAS MF
AZD-9291 AZD-9291 1421373-65-0 C28H33N7O2
Masitinib Masitinib 790299-79-5 C28H30N6OS
Lenvatinib Lenvatinib 417716-92-8 C21H19ClN4O4
Linifanib (ABT-869) Linifanib (ABT-869) 796967-16-3 C21H18FN5O
PELITINIB PELITINIB 257933-82-7 C24H23ClFN5O2
Dacomitinib (PF299804) Dacomitinib (PF299804) 1110813-31-4 C24H25ClFN5O2
Palbociclib Palbociclib 571190-30-2 C24H29N7O2
Pazopanib Hydrochloride Pazopanib Hydrochloride 635702-64-6 C21H24ClN7O2S
Cabozantinib Cabozantinib 849217-68-1 C28H24FN3O5
Tivozanib Tivozanib 475108-18-0 C22H19ClN4O5
Afatinib dimaleate Afatinib dimaleate 850140-73-7 C28H29ClFN5O7
Ceritinib (LDK378) Ceritinib (LDK378) 1032900-25-6 C28H36ClN5O3S
CO-1686 CO-1686 1374640-70-6 C27H28F3N7O3
NVP-TAE684 NVP-TAE684 761439-42-3 C30H40ClN7O3S
Foretinib (GSK1363089) Foretinib (GSK1363089) 849217-64-7 C34H34F2N4O6
Amuvatinib Amuvatinib 850879-09-3 C23H21N5O3S
Alectinib Alectinib 1256580-46-7 C30H34N4O2
WZ4002 WZ4002 1213269-23-8 C25H27ClN6O3
J&J Ex-61 J&J Ex-61 943540-75-8 C19H13F2N7
AEE788 AEE788 497839-62-0 C27H32N6
Crenolanib Crenolanib 670220-88-9 C26H29N5O2
AC480 (BMS-599626) AC480 (BMS-599626) 714971-09-2 C27H27FN8O3
AMG-706 AMG-706 857876-30-3 C22H29N5O9P2
LY 2874455 LY 2874455 1254473-64-7 C21H19Cl2N5O2
AP26113 AP26113 1197958-12-5 C26H34ClN6O2P
GW441756 GW441756 504433-23-2 C17H13N3O
Vatalanib Dihydrochloride Vatalanib Dihydrochloride 212141-51-0 C20H17Cl3N4
Momelotinib Momelotinib 1056634-68-4 C23H22N6O2
AZD8931 AZD8931 848942-61-0 C23H25ClFN5O3
Cabozantinib Malate Cabozantinib Malate 1140909-48-3 C32H30FN3O10
Orantinib (SU6668) Orantinib (SU6668) 252916-29-3 C18H18N2O3
XL518 XL518 934660-93-2 C21H21F3IN3O2
Tucatinib Tucatinib 937263-43-9 C26H24N8O2
SU 11274 SU 11274 658084-23-2 C28H30ClN5O4S
Pixantrone Dimaleate Pixantrone Dimaleate 144675-97-8 C21H23N5O6
SGX-523 SGX-523 1022150-57-7 C18H13N7S
1-Cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 1-Cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 1092788-83-4 C17H17N7
AMG-208 AMG-208 1002304-34-8 C22H17N5O2
R428 R428 1037624-75-1 C30H34N8
AG 1478 HYDROCHLORIDE AG 1478 HYDROCHLORIDE 153436-53-4 C16H14ClN3O2
CP-724714 CP-724714 537705-08-1 C27H27N5O3
PD04217903 PD04217903 956905-27-4 C19H16N8O
TYRPHOSTIN AG 1024 TYRPHOSTIN AG 1024 65678-07-1 C14H13BrN2O
AMG 458 AMG 458 913376-83-7 C30H29N5O5
Linsitinib Linsitinib 867160-71-2 C26H23N5O
Ki8751 Ki8751 228559-41-9 C24H18F3N3O4
IGF-1R  Inhibitor  II,  N-(5-Chloro-2-methoxyphenyl)-Nμ-(2-methylquinolin-4-yl)urea IGF-1R Inhibitor II, N-(5-Chloro-2-methoxyphenyl)-Nμ-(2-methylquinolin-4-yl)urea 196868-63-0 C18H16ClN3O2
(2R)-1-[[5-[(Z)-[5-[[(2,6-DICHLOROPHENYL)METHYL]SULFONYL]-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE]METHYL]-2,4-DIMETHYL-1H-PYRROL-3-YL]CARBONYL]-2-(1-PYRROLIDINYLMETHYL)PYRROLIDINE (2R)-1-[[5-[(Z)-[5-[[(2,6-DICHLOROPHENYL)METHYL]SULFONYL]-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE]METHYL]-2,4-DIMETHYL-1H-PYRROL-3-YL]CARBONYL]-2-(1-PYRROLIDINYLMETHYL)PYRROLIDINE 477575-56-7 C32H34Cl2N4O4S
1-{2-[5-(2-Methoxy-ethoxy)-benzoimidazol-1-yl]-quinolin-8-yl}-piperidin-4-ylamine 1-{2-[5-(2-Methoxy-ethoxy)-benzoimidazol-1-yl]-quinolin-8-yl}-piperidin-4-ylamine 343787-29-1 C24H27N5O2
N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide 875337-44-3 C26H20FN5O2S2
NVP-BHG712 NVP-BHG712 940310-85-0 C26H20F3N7O
Apatinib Apatinib 811803-05-1 C24H23N5O
TYRPHOSTIN AG 1296 TYRPHOSTIN AG 1296 146535-11-7 C16H14N2O2
TYRPHOSTIN AG 879 TYRPHOSTIN AG 879 148741-30-4 C18H24N2OS
BMS-754807 BMS-754807 1001350-96-4 C23H24FN9O
Tie2 kinase inhibitor Tie2 kinase inhibitor 948557-43-5 C26H21N3O2S
BMS-794833 BMS-794833 1174046-72-0 C23H15ClF2N4O3
AVL-292 AVL-292 1202757-89-8 C22H22FN5O3
LRRK2-IN-1 LRRK2-IN-1 1234480-84-2 C31H38N8O3
Golvatinib (E7050) Golvatinib (E7050) 928037-13-2 C33H37F2N7O4
2-(2-ETHYL-2,3-DIHYDRO-2-BENZOFURANYL)-1H-IMIDAZOLE 2-(2-ETHYL-2,3-DIHYDRO-2-BENZOFURANYL)-1H-IMIDAZOLE 189224-48-4 C13H14N2O
Mk-2461  . Mk-2461 . 917879-39-1 C24H25N5O5S
WZ8040 WZ8040 1214265-57-2 C24H25ClN6OS
Insulin-like Growth Factor-1 Receptor Inhibitor Insulin-like Growth Factor-1 Receptor Inhibitor 468740-43-4 C25H26ClN5O3
5-(3-Benzyloxyphenyl)-7-[trans-3-[(pyrrolidin-1-yl)methyl]cyclobutyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine 5-(3-Benzyloxyphenyl)-7-[trans-3-[(pyrrolidin-1-yl)methyl]cyclobutyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine 475488-23-4 C28H31N5O
OSI-420 OSI-420 183320-51-6 C21H22ClN3O4
SR 1078 SR 1078 1246525-60-9 C17H10F9NO2
AST-1306 AST-1306 1050500-29-2 C31H26ClFN4O5S
Poziotinib (HM781-36B) Poziotinib (HM781-36B) 1092364-38-9 C23H21Cl2FN4O3
AVP-AEW541 AVP-AEW541 475489-16-8 C27H29N5O
ALK/IGF1R inhibitor ALK/IGF1R inhibitor 1356962-20-3 C24H25ClN6O
ZM 306416 ZM 306416 690206-97-4 C16H13ClFN3O2
3-[(2,4-Dimethylpyrrol-5-yl)methylidenyl]-2-indolinon 3-[(2,4-Dimethylpyrrol-5-yl)methylidenyl]-2-indolinon 194413-58-6 C15H14N2O
KRN 633 KRN 633 286370-15-8 C20H21ClN4O4
lenvatinib Mesylate lenvatinib Mesylate 857890-39-2 C22H23ClN4O7S
OSI-930 OSI-930 728033-96-3 C22H16F3N3O2S
NVP-BVU 972 NVP-BVU 972 1185763-69-2 C20H16N6
REVERSINE REVERSINE 656820-32-5 C21H27N7O
PD153035 HCl PD153035 HCl 183322-45-4 C16H14BrN3O2.HCl
ARRY-380 ARRY-380 937265-83-3 C29H27N7O4S
NVP-BSK805 NVP-BSK805 1092499-93-8 C27H28F2N6O
3-(1-Methyl-1H-pyrazol-4-yl)-5-oxo-N-(2-pyridinylmethyl)-5H-benzo[4,5]cyclohepta[1,2-b]pyridine-7-methanesulfonamide 3-(1-Methyl-1H-pyrazol-4-yl)-5-oxo-N-(2-pyridinylmethyl)-5H-benzo[4,5]cyclohepta[1,2-b]pyridine-7-methanesulfonamide 1001917-37-8 C25H21N5O3S
N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine 1097917-15-1 C29H40N8O3S
E-3810 E-3810 1058137-23-7 C26H25N3O4
GNF 5837 GNF 5837 1033769-28-6 C28H21F4N5O2
5-[3-Methoxy-4-(4-methoxy-benzyloxy)-benzyl]-pyrimidine-2,4-diamine 5-[3-Methoxy-4-(4-methoxy-benzyloxy)-benzyl]-pyrimidine-2,4-diamine 870483-87-7 C20H22N4O3
Tepotinib Tepotinib 1100598-32-0 C29H28N6O2
GSK1838705A GSK1838705A 1116235-97-2 C27H29FN8O3
TAK-285 TAK-285 871026-44-7 C26H25ClF3N5O3
3-(5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)-pyrrolidine-2,5-dione 3-(5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)-pyrrolidine-2,5-dione 905854-02-6 C23H19N3O2
WZ3146 WZ3146 1214265-56-1 C24H25ClN6O2
GDC-0941 Bimesylate GDC-0941 Bimesylate 957054-33-0 C24H30N7O6S3
Icotinib Icotinib 610798-31-7 C22H21N3O4
UNC2250 UNC2250 1493694-70-4 C24H36N6O2
PD168393 PD168393 194423-15-9 C17H13BrN4O
Capmatinib Capmatinib 1029712-80-8 C23H17FN6O
2-ButynaMide, N-[4-[(3-broMophenyl)aMino]-6-quinazolinyl]- 2-ButynaMide, N-[4-[(3-broMophenyl)aMino]-6-quinazolinyl]- 194423-06-8 C18H13BrN4O
ZM 323881 hydrochloride ZM 323881 hydrochloride 193000-39-4 C22H19ClFN3O2
CNX-2006 CNX-2006 1375465-09-0 C26H27F4N7O2
SKLB1002 SKLB1002 1225451-84-2 C13H12N4O2S2
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