Tubacin
|
- $75 - $2986.9
- Product name: Tubacin
- CAS: 537049-40-4
- MF: C41H43N3O7S
- MW: 721.86
- EINECS:
- MDL Number:MFCD18452824
- Synonyms:Tubacin;N1-(4-((2R,4R,6S)-4-((4,5-diphenyloxazol-2-ylthio)methyl)-6-(4-(hydroxymethyl)phenyl)-1,3-dioxan-2-yl)phenyl)-N8-hydroxyoctanediamide;N1-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N8-hydroxy-octanediamide Tubacin;N1-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N8-hydroxy-octanediamide;Tubacin, >=98%;N1-(4-((2R,4R,6S)-4-(((4,5-Diphenyloxazol-2-yl)thio)methyl)-6-(4-(hydroxymethyl)phenyl)-1,3-di;BML-GR362;Tubacin (BML-GR362)
23 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 500ug
- 1mg
- 2.5mg
- 5mg
- 10mg
- 20mg
- 1
- 25mg
- 100mg
- ManufacturerAK Scientific
- Product number2275AH
- Product descriptionTubacinhydrate
- Packaging25mg
- Price$1384
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4501
- Product descriptionTubacin
- Packaging1mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4501
- Product descriptionTubacin
- Packaging5mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4501
- Product descriptionTubacin
- Packaging10mg
- Price$470
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60354
- Product descriptionTubacin ≥98%
- Packaging5mg
- Price$593
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146282
- Product descriptionTubacin (BML-GR362) >98%
- Packaging100mg
- Price$2986.9
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13691
- Product descriptionTubacin ≥90%
- Packaging1mg
- Price$106
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13691
- Product descriptionTubacin ≥90%
- Packaging5mg
- Price$336
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-5738
- Product descriptionTubacin 99.17%
- Packaging1mg
- Price$96
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5738
- Product descriptionTubacin 99.17%
- Packaging5mg
- Price$324
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5738
- Product descriptionTubacin 99.17%
- Packaging10mg
- Price$612
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5738
- Product descriptionTubacin 99.17%
- Packaging20mg
- Price$1164
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11108880
- Product descriptionTubacin 95+%
- Packaging5mg
- Price$290
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11108880
- Product descriptionTubacin 95+%
- Packaging10mg
- Price$540
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11108880
- Product descriptionTubacin 95+%
- Packaging25mg
- Price$1030
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC5178
- Product descriptionTubacin(BML-GR362) >98%
- Packaging100mg
- Price$2000
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2275AH | Tubacinhydrate | 25mg | $1384 | 2021-12-16 | Buy |
| ApexBio Technology | A4501 | Tubacin | 1mg | $75 | 2021-12-16 | Buy |
| ApexBio Technology | A4501 | Tubacin | 5mg | $250 | 2021-12-16 | Buy |
| ApexBio Technology | A4501 | Tubacin | 10mg | $470 | 2021-12-16 | Buy |
| Arctom | CFN60354 | Tubacin ≥98% | 5mg | $593 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146282 | Tubacin (BML-GR362) >98% | 100mg | $2986.9 | 2021-12-16 | Buy |
| Cayman Chemical | 13691 | Tubacin ≥90% | 1mg | $106 | 2024-03-01 | Buy |
| Cayman Chemical | 13691 | Tubacin ≥90% | 5mg | $336 | 2024-03-01 | Buy |
| ChemScene | CS-5738 | Tubacin 99.17% | 1mg | $96 | 2021-12-16 | Buy |
| ChemScene | CS-5738 | Tubacin 99.17% | 5mg | $324 | 2021-12-16 | Buy |
| ChemScene | CS-5738 | Tubacin 99.17% | 10mg | $612 | 2021-12-16 | Buy |
| ChemScene | CS-5738 | Tubacin 99.17% | 20mg | $1164 | 2021-12-16 | Buy |
| Crysdot | CD11108880 | Tubacin 95+% | 5mg | $290 | 2021-12-16 | Buy |
| Crysdot | CD11108880 | Tubacin 95+% | 10mg | $540 | 2021-12-16 | Buy |
| Crysdot | CD11108880 | Tubacin 95+% | 25mg | $1030 | 2021-12-16 | Buy |
| DC Chemicals | DC5178 | Tubacin(BML-GR362) >98% | 100mg | $2000 | 2021-12-16 | Buy |
Properties
Melting point :155 - 157°C
storage temp. :-20°C
solubility :DMSO: ≥10mg/mL
form :powder
color :white to tan
InChIKey :BHUZLJOUHMBZQY-UHHSDZQINA-N
SMILES :C(NC1=CC=C([C@H]2O[C@@H](CSC3=NC(C4=CC=CC=C4)=C(C4=CC=CC=C4)O3)C[C@@H](C3=CC=C(CO)C=C3)O2)C=C1)(=O)CCCCCCC(NO)=O |&1:6,8,29,r|
storage temp. :-20°C
solubility :DMSO: ≥10mg/mL
form :powder
color :white to tan
InChIKey :BHUZLJOUHMBZQY-UHHSDZQINA-N
SMILES :C(NC1=CC=C([C@H]2O[C@@H](CSC3=NC(C4=CC=CC=C4)=C(C4=CC=CC=C4)O3)C[C@@H](C3=CC=C(CO)C=C3)O2)C=C1)(=O)CCCCCCC(NO)=O |&1:6,8,29,r|
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | ||||||||||||||
| Hazard statements: |
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| Precautionary statements: |
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Description
Tubacin is a tubulin acetylation inducer that selectively inhibits histone deacetylase (HDAC) 6 (IC50 = 4 nM). In comparison, it demonstrates at least 300-fold selectivity against all other HDAC isoforms (IC50s range from 1.3-17.3 μM). Tubacin induces α-tubulin hyperacetylation at 2.5 μM in primary cortical neuron cultures. Tubacin inhibition of HDAC6 has been used as a biochemical tool to control microtubule-dependent intracellular trafficking, to manipulate the aggresome formation of misfolded proteins in certain diseases, and to study the dynamics of cellular adhesion.Related product price
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