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ChemicalBook >> CAS DataBase List >> BENZOTRIAZOL-1-YL-(2,4-DICHLORO-PHENYL)-METHANONE

BENZOTRIAZOL-1-YL-(2,4-DICHLORO-PHENYL)-METHANONE

BENZOTRIAZOL-1-YL-(2,4-DICHLORO-PHENYL)-METHANONE price.
  • $44 - $710
  • Product name: BENZOTRIAZOL-1-YL-(2,4-DICHLORO-PHENYL)-METHANONE
  • CAS: 200626-61-5
  • MF: C13H7Cl2N3O
  • MW: 292.12
  • EINECS:
  • MDL Number:MFCD00195103
  • Synonyms:IFLAB-BB F0451-3184;BENZOTRIAZOL-1-YL-(2,4-DICHLORO-PHENYL)-METHANONE;1-(2,4-Dichlorobenzoyl)-1H-benzotriazole;ITSA-1(ITSA1);CS-2249;Methanone, 1H-benzotriazol-1-yl(2,4-dichlorophenyl)-;(1H-Benzo[d][1,2,3]triazol-1-yl)(2,4-dichlorophenyl)methanone;inhibit,Histone deacetylases,ITSA-1,Inhibitor,HDAC,ITSA 1
23 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
Package
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number9078BA
  • Product descriptionN-(1H-Benzotriazol-1-yl)-2,4-dichlorobenzamide
  • Packaging100mg
  • Price$147
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA879167
  • Product descriptionITSA-1 99+%
  • Packaging10mg
  • Price$44
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA879167
  • Product descriptionITSA-1 99+%
  • Packaging25mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA879167
  • Product descriptionITSA-1 99+%
  • Packaging50mg
  • Price$76
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA879167
  • Product descriptionITSA-1 99+%
  • Packaging100mg
  • Price$98
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA879167
  • Product descriptionITSA-1 99+%
  • Packaging250mg
  • Price$146
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA879167
  • Product descriptionITSA-1 99+%
  • Packaging1g
  • Price$710
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7816
  • Product descriptionITSA-1(ITSA1)
  • Packaging10mg
  • Price$79
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7816
  • Product descriptionITSA-1(ITSA1)
  • Packaging25mg
  • Price$134
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7816
  • Product descriptionITSA-1(ITSA1)
  • Packaging50mg
  • Price$205
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7816
  • Product descriptionITSA-1(ITSA1)
  • Packaging100mg
  • Price$347
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18681
  • Product descriptionITSA1 ≥95%
  • Packaging10mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18681
  • Product descriptionITSA1 ≥95%
  • Packaging25mg
  • Price$92
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18681
  • Product descriptionITSA1 ≥95%
  • Packaging50mg
  • Price$161
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18681
  • Product descriptionITSA1 ≥95%
  • Packaging100mg
  • Price$257
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5854
  • Product descriptionITSA-1 >98.0%
  • Packaging10mg
  • Price$60
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9078BA N-(1H-Benzotriazol-1-yl)-2,4-dichlorobenzamide 100mg $147 2021-12-16 Buy
Ambeed A879167 ITSA-1 99+% 10mg $44 2021-12-16 Buy
Ambeed A879167 ITSA-1 99+% 25mg $59 2021-12-16 Buy
Ambeed A879167 ITSA-1 99+% 50mg $76 2021-12-16 Buy
Ambeed A879167 ITSA-1 99+% 100mg $98 2021-12-16 Buy
Ambeed A879167 ITSA-1 99+% 250mg $146 2021-12-16 Buy
Ambeed A879167 ITSA-1 99+% 1g $710 2021-12-16 Buy
ApexBio Technology B7816 ITSA-1(ITSA1) 10mg $79 2021-12-16 Buy
ApexBio Technology B7816 ITSA-1(ITSA1) 25mg $134 2021-12-16 Buy
ApexBio Technology B7816 ITSA-1(ITSA1) 50mg $205 2021-12-16 Buy
ApexBio Technology B7816 ITSA-1(ITSA1) 100mg $347 2021-12-16 Buy
Cayman Chemical 18681 ITSA1 ≥95% 10mg $44 2024-03-01 Buy
Cayman Chemical 18681 ITSA1 ≥95% 25mg $92 2024-03-01 Buy
Cayman Chemical 18681 ITSA1 ≥95% 50mg $161 2024-03-01 Buy
Cayman Chemical 18681 ITSA1 ≥95% 100mg $257 2024-03-01 Buy
ChemScene CS-5854 ITSA-1 >98.0% 10mg $60 2021-12-16 Buy

Properties

Melting point :119-121°C
storage temp. :Inert atmosphere,2-8°C
solubility :DMSO: ~28mg/mL
form :solid
color :White to Off-White

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Trichostatin A (TSA; ) is a potent, reversible inhibitor of histone deacetylase (HDAC) that inhibits HDAC1 (IC50 = 70 nM) in Jurkat cells, resulting in cell cycle arrest. ITSA1 is a cell-permeable benzotriazole amide that blocks TSA action, reducing TSA-induced acetylation of histone and tubulin in A549 cells when given at 50 μM. At the same concentration, ITSA1 also prevents TSA-mediated cell cycle arrest and apoptosis. It similarly blocks the action of the HDAC inhibitor SAHA , preventing SAHA-induced hyperacetylation of tubulin in A549 cells. ITSA1 reduces TSA-regulated transcription in mouse embryonic stem cells and in zebrafish.

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