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ChemicalBook >> CAS DataBase List >> Entinostat

Entinostat

Entinostat price.
  • $21 - $1963.5
  • Product name: Entinostat
  • CAS: 209783-80-2
  • MF: C21H20N4O3
  • MW: 376.41
  • EINECS:
  • MDL Number:MFCD08272435
  • Synonyms:Carbamic acid, N-[[4-[[(2-aminophenyl)amino]carbonyl]phenyl]methyl]-, 3-pyridinylmethyl ester;entinostat;3-pyridinylmethyl [[4-[[(2-aminophenyl)amino]carbonyl]phenyl]methyl]carbamate, N-(2-Aminophenyl)-4-[N-(pyridine-3ylmethoxycarbonyl)aminomethyl]benzamide;N-[[4-[[(2-Aminophenyl)amino]carbonyl]phenyl]methyl]carbamic acid 3-pyridinylmethyl ester;Entinostat/MS-275;Nsc706995;Entinostat(NSC-706995);(Pyridin-3-yl)Methyl 4-(2-AMinophenylcarbaMoyl)benzylcarbaMate
43 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
  • 1unit
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberJ97909
  • Product descriptionEntinostat
  • Packaging100mg
  • Price$144
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA122285
  • Product descriptionPyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate 98+%
  • Packaging10mg
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA122285
  • Product descriptionPyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate 98+%
  • Packaging50mg
  • Price$58
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA122285
  • Product descriptionPyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate 98+%
  • Packaging100mg
  • Price$87
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA122285
  • Product descriptionPyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate 98+%
  • Packaging250mg
  • Price$132
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA122285
  • Product descriptionPyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate 98+%
  • Packaging1g
  • Price$333
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000350
  • Product descriptionMS-275 95.00%
  • Packaging1G
  • Price$1963.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000350
  • Product descriptionMS-275 95.00%
  • Packaging100MG
  • Price$750.75
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000350
  • Product descriptionMS-275 95.00%
  • Packaging5MG
  • Price$188.1
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8171
  • Product descriptionEntinostat(MS-275,SNDX-275)
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8171
  • Product descriptionEntinostat(MS-275,SNDX-275)
  • Packaging10mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS023212
  • Product descriptionPyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate ≥98%
  • Packaging10mg
  • Price$31
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS023212
  • Product descriptionPyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate ≥98%
  • Packaging50mg
  • Price$51
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS023212
  • Product descriptionPyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate ≥98%
  • Packaging100mg
  • Price$92
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS023212
  • Product descriptionPyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate ≥98%
  • Packaging250mg
  • Price$154
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60024
  • Product descriptionEntinostat(MS-275) ≥98%
  • Packaging10mg
  • Price$168
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J97909 Entinostat 100mg $144 2021-12-16 Buy
Ambeed A122285 Pyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate 98+% 10mg $25 2021-12-16 Buy
Ambeed A122285 Pyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate 98+% 50mg $58 2021-12-16 Buy
Ambeed A122285 Pyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate 98+% 100mg $87 2021-12-16 Buy
Ambeed A122285 Pyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate 98+% 250mg $132 2021-12-16 Buy
Ambeed A122285 Pyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate 98+% 1g $333 2021-12-16 Buy
American Custom Chemicals Corporation INB0000350 MS-275 95.00% 1G $1963.5 2021-12-16 Buy
American Custom Chemicals Corporation INB0000350 MS-275 95.00% 100MG $750.75 2021-12-16 Buy
American Custom Chemicals Corporation INB0000350 MS-275 95.00% 5MG $188.1 2021-12-16 Buy
ApexBio Technology A8171 Entinostat(MS-275,SNDX-275) 1unit $28 2021-12-16 Buy
ApexBio Technology A8171 Entinostat(MS-275,SNDX-275) 10mg $50 2021-12-16 Buy
Arctom AS023212 Pyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate ≥98% 10mg $31 2021-12-16 Buy
Arctom AS023212 Pyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate ≥98% 50mg $51 2021-12-16 Buy
Arctom AS023212 Pyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate ≥98% 100mg $92 2021-12-16 Buy
Arctom AS023212 Pyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate ≥98% 250mg $154 2021-12-16 Buy
Arctom CFN60024 Entinostat(MS-275) ≥98% 10mg $168 2021-12-16 Buy

Properties

Melting point :159-160 ºC
Boiling point :566.7±50.0 °C(Predicted)
Density :1.315
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: 38 mg/mL, soluble
form :solid
pka :11.32±0.46(Predicted)
color :Pale yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week.
InChIKey :INVTYAOGFAGBOE-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.

Description

MS-275 is an inhibitor of histone deacetylases (HDACs) that preferentially inhibits HDAC1 (IC50 = 300 nM) over HDAC3 (IC50 = 8 μM). However, it does not inhibit HDAC8 (IC50 > 100 μM). MS-275 induces cyclin-dependent kinase inhibitor 1A (p21/CIP1/WAF1), slowing cell growth, differentiation, and tumor development in vivo. Recent studies suggest that MS-275 may be particularly useful as an antineoplastic agent when combined with other drugs, like adriamycin, inhibitors of poly (ADP-ribose) polymerase (PARP), or inhibitors of heat shock protein 90 (Hsp90).

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