Entinostat
- $21 - $1963.5
- Product name: Entinostat
- CAS: 209783-80-2
- MF: C21H20N4O3
- MW: 376.41
- EINECS:
- MDL Number:MFCD08272435
- Synonyms:Carbamic acid, N-[[4-[[(2-aminophenyl)amino]carbonyl]phenyl]methyl]-, 3-pyridinylmethyl ester;entinostat;3-pyridinylmethyl [[4-[[(2-aminophenyl)amino]carbonyl]phenyl]methyl]carbamate, N-(2-Aminophenyl)-4-[N-(pyridine-3ylmethoxycarbonyl)aminomethyl]benzamide;N-[[4-[[(2-Aminophenyl)amino]carbonyl]phenyl]methyl]carbamic acid 3-pyridinylmethyl ester;Entinostat/MS-275;Nsc706995;Entinostat(NSC-706995);(Pyridin-3-yl)Methyl 4-(2-AMinophenylcarbaMoyl)benzylcarbaMate
43 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 1mg
- 1unit
- 5MG
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- ManufacturerAK Scientific
- Product numberJ97909
- Product descriptionEntinostat
- Packaging100mg
- Price$144
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA122285
- Product descriptionPyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate 98+%
- Packaging10mg
- Price$25
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA122285
- Product descriptionPyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate 98+%
- Packaging50mg
- Price$58
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA122285
- Product descriptionPyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate 98+%
- Packaging100mg
- Price$87
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA122285
- Product descriptionPyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate 98+%
- Packaging250mg
- Price$132
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA122285
- Product descriptionPyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate 98+%
- Packaging1g
- Price$333
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000350
- Product descriptionMS-275 95.00%
- Packaging1G
- Price$1963.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000350
- Product descriptionMS-275 95.00%
- Packaging100MG
- Price$750.75
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000350
- Product descriptionMS-275 95.00%
- Packaging5MG
- Price$188.1
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8171
- Product descriptionEntinostat(MS-275,SNDX-275)
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8171
- Product descriptionEntinostat(MS-275,SNDX-275)
- Packaging10mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS023212
- Product descriptionPyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate ≥98%
- Packaging10mg
- Price$31
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS023212
- Product descriptionPyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate ≥98%
- Packaging50mg
- Price$51
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS023212
- Product descriptionPyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate ≥98%
- Packaging100mg
- Price$92
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS023212
- Product descriptionPyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate ≥98%
- Packaging250mg
- Price$154
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60024
- Product descriptionEntinostat(MS-275) ≥98%
- Packaging10mg
- Price$168
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | J97909 | Entinostat | 100mg | $144 | 2021-12-16 | Buy |
Ambeed | A122285 | Pyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate 98+% | 10mg | $25 | 2021-12-16 | Buy |
Ambeed | A122285 | Pyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate 98+% | 50mg | $58 | 2021-12-16 | Buy |
Ambeed | A122285 | Pyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate 98+% | 100mg | $87 | 2021-12-16 | Buy |
Ambeed | A122285 | Pyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate 98+% | 250mg | $132 | 2021-12-16 | Buy |
Ambeed | A122285 | Pyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate 98+% | 1g | $333 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0000350 | MS-275 95.00% | 1G | $1963.5 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0000350 | MS-275 95.00% | 100MG | $750.75 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0000350 | MS-275 95.00% | 5MG | $188.1 | 2021-12-16 | Buy |
ApexBio Technology | A8171 | Entinostat(MS-275,SNDX-275) | 1unit | $28 | 2021-12-16 | Buy |
ApexBio Technology | A8171 | Entinostat(MS-275,SNDX-275) | 10mg | $50 | 2021-12-16 | Buy |
Arctom | AS023212 | Pyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate ≥98% | 10mg | $31 | 2021-12-16 | Buy |
Arctom | AS023212 | Pyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate ≥98% | 50mg | $51 | 2021-12-16 | Buy |
Arctom | AS023212 | Pyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate ≥98% | 100mg | $92 | 2021-12-16 | Buy |
Arctom | AS023212 | Pyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate ≥98% | 250mg | $154 | 2021-12-16 | Buy |
Arctom | CFN60024 | Entinostat(MS-275) ≥98% | 10mg | $168 | 2021-12-16 | Buy |
Properties
Melting point :159-160 ºC
Boiling point :566.7±50.0 °C(Predicted)
Density :1.315
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: 38 mg/mL, soluble
form :solid
pka :11.32±0.46(Predicted)
color :Pale yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week.
InChIKey :INVTYAOGFAGBOE-UHFFFAOYSA-N
Boiling point :566.7±50.0 °C(Predicted)
Density :1.315
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: 38 mg/mL, soluble
form :solid
pka :11.32±0.46(Predicted)
color :Pale yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week.
InChIKey :INVTYAOGFAGBOE-UHFFFAOYSA-N
Safety Information
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Signal word: | Danger | |||||||||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
MS-275 is an inhibitor of histone deacetylases (HDACs) that preferentially inhibits HDAC1 (IC50 = 300 nM) over HDAC3 (IC50 = 8 μM). However, it does not inhibit HDAC8 (IC50 > 100 μM). MS-275 induces cyclin-dependent kinase inhibitor 1A (p21/CIP1/WAF1), slowing cell growth, differentiation, and tumor development in vivo. Recent studies suggest that MS-275 may be particularly useful as an antineoplastic agent when combined with other drugs, like adriamycin, inhibitors of poly (ADP-ribose) polymerase (PARP), or inhibitors of heat shock protein 90 (Hsp90).More related product prices
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