Luliconazole
|
- $8 - $1172
- Product name: Luliconazole
- CAS: 187164-19-8
- MF: C14H9Cl2N3S2
- MW: 354.27
- EINECS:247-960-9
- MDL Number:MFCD00953915
- Synonyms:Luliconazole;(2E)-2-[(4R)-4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene]-2-imidazol-1-ylacetonitrile;4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene-1-imidazolylacetonitrile;C13478;Lulicon;NND 502;1H-Imidazole-1-acetonitrile,a-[(4R)-4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene]-,(aE)-;Luliconazole (This product is only available in Japan.)
30 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Labseeker
- Medical Isotopes, Inc.
- TCI Chemical
- TRC
- Usbiological
Package
- 10mg
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 10mM(in 1mL DMSO)
- 1g
- 5g
- 50g
- ManufacturerAK Scientific
- Product numberZ3687
- Product descriptionLuliconazole
- Packaging1g
- Price$417
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA170757
- Product description(R,E)-2-(4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene)-2-(1H-imidazol-1-yl)acetonitrile 98+%
- Packaging10mg
- Price$8
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA170757
- Product description(R,E)-2-(4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene)-2-(1H-imidazol-1-yl)acetonitrile 98+%
- Packaging50mg
- Price$13
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA170757
- Product description(R,E)-2-(4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene)-2-(1H-imidazol-1-yl)acetonitrile 98+%
- Packaging100mg
- Price$16
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA170757
- Product description(R,E)-2-(4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene)-2-(1H-imidazol-1-yl)acetonitrile 98+%
- Packaging250mg
- Price$27
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA170757
- Product description(R,E)-2-(4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene)-2-(1H-imidazol-1-yl)acetonitrile 98+%
- Packaging1g
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA170757
- Product description(R,E)-2-(4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene)-2-(1H-imidazol-1-yl)acetonitrile 98+%
- Packaging5g
- Price$211
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0005103
- Product descriptionLULICONAZOLE 95.00%
- Packaging50MG
- Price$224.7
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0005103
- Product descriptionLULICONAZOLE 95.00%
- Packaging5G
- Price$909.56
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3564
- Product descriptionLuliconazole
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS015890
- Product description(R,E)-2-(4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene)-2-(1H-imidazol-1-yl)acetonitrile ≥98%
- Packaging1g
- Price$59
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS015890
- Product description(R,E)-2-(4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene)-2-(1H-imidazol-1-yl)acetonitrile ≥98%
- Packaging5g
- Price$209
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number23120
- Product descriptionLuliconazole ≥98%
- Packaging250mg
- Price$86
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23120
- Product descriptionLuliconazole ≥98%
- Packaging500mg
- Price$152
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23120
- Product descriptionLuliconazole ≥98%
- Packaging1g
- Price$287
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23120
- Product descriptionLuliconazole ≥98%
- Packaging5g
- Price$1172
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | Z3687 | Luliconazole | 1g | $417 | 2021-12-16 | Buy |
| Ambeed | A170757 | (R,E)-2-(4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene)-2-(1H-imidazol-1-yl)acetonitrile 98+% | 10mg | $8 | 2021-12-16 | Buy |
| Ambeed | A170757 | (R,E)-2-(4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene)-2-(1H-imidazol-1-yl)acetonitrile 98+% | 50mg | $13 | 2021-12-16 | Buy |
| Ambeed | A170757 | (R,E)-2-(4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene)-2-(1H-imidazol-1-yl)acetonitrile 98+% | 100mg | $16 | 2021-12-16 | Buy |
| Ambeed | A170757 | (R,E)-2-(4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene)-2-(1H-imidazol-1-yl)acetonitrile 98+% | 250mg | $27 | 2021-12-16 | Buy |
| Ambeed | A170757 | (R,E)-2-(4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene)-2-(1H-imidazol-1-yl)acetonitrile 98+% | 1g | $60 | 2021-12-16 | Buy |
| Ambeed | A170757 | (R,E)-2-(4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene)-2-(1H-imidazol-1-yl)acetonitrile 98+% | 5g | $211 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0005103 | LULICONAZOLE 95.00% | 50MG | $224.7 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0005103 | LULICONAZOLE 95.00% | 5G | $909.56 | 2021-12-16 | Buy |
| ApexBio Technology | A3564 | Luliconazole | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
| Arctom | AS015890 | (R,E)-2-(4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene)-2-(1H-imidazol-1-yl)acetonitrile ≥98% | 1g | $59 | 2021-12-16 | Buy |
| Arctom | AS015890 | (R,E)-2-(4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene)-2-(1H-imidazol-1-yl)acetonitrile ≥98% | 5g | $209 | 2021-12-16 | Buy |
| Cayman Chemical | 23120 | Luliconazole ≥98% | 250mg | $86 | 2024-03-01 | Buy |
| Cayman Chemical | 23120 | Luliconazole ≥98% | 500mg | $152 | 2024-03-01 | Buy |
| Cayman Chemical | 23120 | Luliconazole ≥98% | 1g | $287 | 2024-03-01 | Buy |
| Cayman Chemical | 23120 | Luliconazole ≥98% | 5g | $1172 | 2024-03-01 | Buy |
Properties
Melting point :152 °C
Boiling point :499.1±55.0 °C(Predicted)
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly)
form :Solid
pka :3.76±0.10(Predicted)
color :White to Off-White
Stability :Light Sensitive
CAS DataBase Reference :187164-19-8
Boiling point :499.1±55.0 °C(Predicted)
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly)
form :Solid
pka :3.76±0.10(Predicted)
color :White to Off-White
Stability :Light Sensitive
CAS DataBase Reference :187164-19-8
Safety Information
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Description
Luliconazole is a member of the imidazole class of antifungal agents, with specific utility as a dermatological antimycotic drug. It was launched in Japan as a topical agent for the treatment of athlete’s foot. Luliconazole is an optically active drug with (R)-configuration at its chiral center. It is structurally related to lanoconazole, which has been marketed as a racemic mixture since 1994. As with other azole antifungal drugs, the mechanism of action of luliconazole is the inhibition of sterol 14-a-demethylase, and subsequently, inhibition of ergosterol biosynthesis. The in vivo activity of luliconazole against dermatophytes has been evaluated in the guinea pig model of tinea pedis. In this study, a 1% topical solution of luliconazole, administered once daily for seven days, achieved complete mycologic cure. Additionally, there were no occurrences of relapse for up to 16 weeks after the treatment. No data is currently available on the clinical efficacy of luliconazole. The chemical synthesis of luliconazole involves the condensation of 1-(cyanomethyl)imidazole with carbon disulfide to produce a dithioate intermediate, and subsequent alkylation with either the mesylate derivative of (S′)-1-(2,4-dichlorophenyl)-2-bromoethanol or the bis-mesylate derivative of (S′)-1-(2,4-dichlorophenyl)ethane-1,2-diol. .Related product price
- Dichlorodiphenylsilane
$10-725 - Imidazole
$5-19203 - Miconazole nitrate
$33-690
Suppliers and manufacturers
Beijing Cooperate Pharmaceutical Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
Hangzhou FandaChem Co.,Ltd.
TianYuan Pharmaceutical CO.,LTD
Biochempartner
Hubei Jusheng Technology Co.,Ltd.
