INDIRUBIN-3'-MONOXIME
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- $48 - $2100
- Product name: INDIRUBIN-3'-MONOXIME
- CAS: 160807-49-8
- MF: C16H11N3O2
- MW: 277.28
- EINECS:
- MDL Number:MFCD02683594
- Synonyms:3-[1,3-DIHYDRO-3-(HYDROXYIMINO)-2H-INDOL-2-YLIDENE]-1,3-DIHYDRO-2H-INDOL-2-ONE;INDIRUBIN-3'-MONOXIME;INDIRUBIN-3'-OXIME;Indirubine-3'-oxime;INDIRUBIN-3’-MONOOXIME;Indirubin-3;3-(Hydroxyimino)-[2,3'-biindolinylidene]-2'-one;Indirubin-3-monoxime - CAS 160807-49-8 - Calbiochem
36 prices
Selected condition：
Brand
- AK Scientific
- Alfa Aesar
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
Package
- 10
- 2mg
- 1mg
- 50
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 1g
- ManufacturerAK Scientific
- Product number1800AH
- Product descriptionIndirubin-3?-monoxime
- Packaging25mg
- Price$365
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ67459
- Product descriptionIndirubin-3'-oxime, 98%
- Packaging5mg
- Price$180.65
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ67459
- Product descriptionIndirubin-3'-oxime, 98%
- Packaging10mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA738539
- Product description3-(Hydroxyimino)-[2,3'-biindolinylidene]-2'-one 98%
- Packaging5mg
- Price$105
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA738539
- Product description3-(Hydroxyimino)-[2,3'-biindolinylidene]-2'-one 98%
- Packaging10mg
- Price$146
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA738539
- Product description3-(Hydroxyimino)-[2,3'-biindolinylidene]-2'-one 98%
- Packaging25mg
- Price$247
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA738539
- Product description3-(Hydroxyimino)-[2,3'-biindolinylidene]-2'-one 98%
- Packaging50mg
- Price$369
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000132
- Product descriptionIndirubin-3?-monoxime 95.00%
- Packaging5MG
- Price$647.96
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000132
- Product descriptionIndirubin-3?-monoxime 95.00%
- Packaging10MG
- Price$798
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000132
- Product descriptionIndirubin-3?-monoxime 95.00%
- Packaging50MG
- Price$1127.86
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6865
- Product descriptionIndirubin-3'-oxime
- Packaging5mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6865
- Product descriptionIndirubin-3'-oxime
- Packaging10mg
- Price$173
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6865
- Product descriptionIndirubin-3'-oxime
- Packaging50mg
- Price$693
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611725
- Product descriptionIndirubin-3?-monoxime
- Packaging10mg
- Price$248.2
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611725
- Product descriptionIndirubin-3?-monoxime
- Packaging50mg
- Price$544
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13314
- Product descriptionIndirubin-3?-monoxime ≥98%
- Packaging1mg
- Price$48
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 1800AH | Indirubin-3?-monoxime | 25mg | $365 | 2021-12-16 | Buy |
| Alfa Aesar | J67459 | Indirubin-3'-oxime, 98% | 5mg | $180.65 | 2024-03-01 | Buy |
| Alfa Aesar | J67459 | Indirubin-3'-oxime, 98% | 10mg | $200 | 2021-12-16 | Buy |
| Ambeed | A738539 | 3-(Hydroxyimino)-[2,3'-biindolinylidene]-2'-one 98% | 5mg | $105 | 2021-12-16 | Buy |
| Ambeed | A738539 | 3-(Hydroxyimino)-[2,3'-biindolinylidene]-2'-one 98% | 10mg | $146 | 2021-12-16 | Buy |
| Ambeed | A738539 | 3-(Hydroxyimino)-[2,3'-biindolinylidene]-2'-one 98% | 25mg | $247 | 2021-12-16 | Buy |
| Ambeed | A738539 | 3-(Hydroxyimino)-[2,3'-biindolinylidene]-2'-one 98% | 50mg | $369 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000132 | Indirubin-3?-monoxime 95.00% | 5MG | $647.96 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000132 | Indirubin-3?-monoxime 95.00% | 10MG | $798 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000132 | Indirubin-3?-monoxime 95.00% | 50MG | $1127.86 | 2021-12-16 | Buy |
| ApexBio Technology | B6865 | Indirubin-3'-oxime | 5mg | $110 | 2021-12-16 | Buy |
| ApexBio Technology | B6865 | Indirubin-3'-oxime | 10mg | $173 | 2021-12-16 | Buy |
| ApexBio Technology | B6865 | Indirubin-3'-oxime | 50mg | $693 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611725 | Indirubin-3?-monoxime | 10mg | $248.2 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611725 | Indirubin-3?-monoxime | 50mg | $544 | 2021-12-16 | Buy |
| Cayman Chemical | 13314 | Indirubin-3?-monoxime ≥98% | 1mg | $48 | 2024-03-01 | Buy |
Properties
Melting point :247-249°C
Boiling point :532.2±50.0 °C(Predicted)
Density :1.50
storage temp. :room temp
solubility :DMSO: >10 mg/mL
form :solid
pka :8.66±0.20(Predicted)
color :Dark red or brown
Stability :Light Sensitive
CAS DataBase Reference :160807-49-8
Boiling point :532.2±50.0 °C(Predicted)
Density :1.50
storage temp. :room temp
solubility :DMSO: >10 mg/mL
form :solid
pka :8.66±0.20(Predicted)
color :Dark red or brown
Stability :Light Sensitive
CAS DataBase Reference :160807-49-8
Safety Information
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Description
Indirubin-3’-oxime is a potent inhibitor of glycogen synthase kinase 3β (GSK3β; IC50 = 22 nM). As GSK3β phosphorylates tau protein, indirubin-3’-oxime prevents tau phosphorylation both in vitro and in vivo at Alzheimer’s disease-relevant sites. It also inhibits cyclin-dependent kinases (CDKs) at higher concentrations, including Cdk1/cyclin B (IC50 = 180 nM), Cdk2/cyclin A (IC50 ~500 nM), Cdk2/cyclin E (IC50 = 250nM), Cdk4/cyclin D1 (IC50 = 3.3 μM) and Cdk5/p35 (IC50 = 100 nM). Indirubin-3’-oxime reversibly inhibits the proliferation of many cells types, arresting cycling in the G2/M phase.More related product prices
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Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
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