Axitinib
|
- $39 - $1154
- Product name: Axitinib
- CAS: 319460-85-0
- MF: C22H18N4OS
- MW: 386.47
- EINECS:638-771-6
- MDL Number:MFCD09837898
- Synonyms:N-METHYL-2-{[3-((E)-2-PYRIDIN-2-YLVINYL)-1H-INDAZOL-6-YL]SULFANYL}BENZAMIDE;AVERMECTINB;Axitinib for research;AG 013736;Benzamide, N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-;Axtinib;N-Methyl-2-({3-[(E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-6-yl}sulfanyl)benzaMide;10MG/50MG/100G
45 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemcia Scientific
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- Usbiological
Package
- 5mg
- 10MG
- 50mg
- 20mg
- 50
- 10
- 100mg
- 10mM(in 1mL DMSO)
- 200mg
- 250mg
- 500mg
- 1g
- 5g
- ManufacturerAK Scientific
- Product numberJ11463
- Product descriptionAxitinib
- Packaging100mg
- Price$156
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberA819
- Product descriptionAxitinib
- Packaging250mg
- Price$187
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ99425
- Product descriptionAxitinib
- Packaging1g
- Price$360
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024707
- Product descriptionAXITINIB 95.00%
- Packaging10MG
- Price$779.63
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024707
- Product descriptionAXITINIB 95.00%
- Packaging1G
- Price$854.7
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8370
- Product descriptionAxitinib(AG013736)
- Packaging100mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8370
- Product descriptionAxitinib(AG013736)
- Packaging10mM(in 1mL DMSO)
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8370
- Product descriptionAxitinib(AG013736)
- Packaging50mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60145
- Product descriptionAxitinib
- Packaging20mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS484876
- Product description(E)-N-Methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide ≥98%
- Packaging100mg
- Price$105
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS484876
- Product description(E)-N-Methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide ≥98%
- Packaging250mg
- Price$138
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS484876
- Product description(E)-N-Methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide ≥98%
- Packaging1g
- Price$355
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS484876
- Product description(E)-N-Methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide ≥98%
- Packaging5g
- Price$1154
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2431
- Product descriptionAxitinib
- Packaging10mg
- Price$39
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2431
- Product descriptionAxitinib
- Packaging100mg
- Price$69
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2431
- Product descriptionAxitinib
- Packaging1g
- Price$375
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | J11463 | Axitinib | 100mg | $156 | 2021-12-16 | Buy |
| AK Scientific | A819 | Axitinib | 250mg | $187 | 2021-12-16 | Buy |
| AK Scientific | J99425 | Axitinib | 1g | $360 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0024707 | AXITINIB 95.00% | 10MG | $779.63 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0024707 | AXITINIB 95.00% | 1G | $854.7 | 2021-12-16 | Buy |
| ApexBio Technology | A8370 | Axitinib(AG013736) | 100mg | $85 | 2021-12-16 | Buy |
| ApexBio Technology | A8370 | Axitinib(AG013736) | 10mM(in 1mL DMSO) | $55 | 2021-12-16 | Buy |
| ApexBio Technology | A8370 | Axitinib(AG013736) | 50mg | $50 | 2021-12-16 | Buy |
| Arctom | CFN60145 | Axitinib | 20mg | $70 | 2021-12-16 | Buy |
| Arctom | AS484876 | (E)-N-Methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide ≥98% | 100mg | $105 | 2021-12-16 | Buy |
| Arctom | AS484876 | (E)-N-Methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide ≥98% | 250mg | $138 | 2021-12-16 | Buy |
| Arctom | AS484876 | (E)-N-Methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide ≥98% | 1g | $355 | 2021-12-16 | Buy |
| Arctom | AS484876 | (E)-N-Methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide ≥98% | 5g | $1154 | 2021-12-16 | Buy |
| AvaChem | 2431 | Axitinib | 10mg | $39 | 2021-12-16 | Buy |
| AvaChem | 2431 | Axitinib | 100mg | $69 | 2021-12-16 | Buy |
| AvaChem | 2431 | Axitinib | 1g | $375 | 2021-12-16 | Buy |
Properties
Melting point :213-215°C
Boiling point :668.9±55.0 °C(Predicted)
Density :1.4
storage temp. :room temp
solubility :DMSO: ≥8mg/mL
form :powder
pka :12.70±0.40(Predicted)
color :white to tan
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C22H18N4OS/c1-23-22(27)18-7-2-3-8-21(18)28-16-10-11-17-19(25-26-20(17)14-16)12-9-15-6-4-5-13-24-15/h2-14H,1H3,(H,23,27)(H,25,26)/b12-9+
InChIKey :RITAVMQDGBJQJZ-FMIVXFBMSA-N
SMILES :C(NC)(=O)C1=CC=CC=C1SC1=CC2=C(C=C1)C(/C=C/C1=NC=CC=C1)=NN2
CAS DataBase Reference :319460-85-0(CAS DataBase Reference)
Boiling point :668.9±55.0 °C(Predicted)
Density :1.4
storage temp. :room temp
solubility :DMSO: ≥8mg/mL
form :powder
pka :12.70±0.40(Predicted)
color :white to tan
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C22H18N4OS/c1-23-22(27)18-7-2-3-8-21(18)28-16-10-11-17-19(25-26-20(17)14-16)12-9-15-6-4-5-13-24-15/h2-14H,1H3,(H,23,27)(H,25,26)/b12-9+
InChIKey :RITAVMQDGBJQJZ-FMIVXFBMSA-N
SMILES :C(NC)(=O)C1=CC=CC=C1SC1=CC2=C(C=C1)C(/C=C/C1=NC=CC=C1)=NN2
CAS DataBase Reference :319460-85-0(CAS DataBase Reference)
Safety Information
| Symbol(GHS): |
 
|
|||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||
| Precautionary statements: |
|
Description
Axitinib is a tyrosine kinase inhibitor that blocks the activation of VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFR-β (IC50 = 1.2, 0.25, 0.29, 1.7, and 1.6 nM, respectively). Through its effects on VEGFRs, it causes regression of fenestrated, VEGFR-rich capillaries in tumors and normal tissue of mice, which is reversed following removal of the inhibitor. Axitinib has shown promise as a therapeutic, in certain cancers and cancer models.More related product prices
Afatinib (BIBW 2992) Crizotinib Sunitinib Malate 871700-17-3 Dasatinib Bosutinib Lenvatinib Dacomitinib (PF299804) OTAVA-BB 1115529 Cabozantinib GZD 824 CO-1686 Neratinib lenvatinib Mesylate Axitinib BenzaMide, 2-[(3-iodo-1H-indazol-6-yl)thio]-N-Methyl- 3,6-DIIODO (1H)INDAZOLE 2-(1H-indazol-6-ylthio)-N-Methyl- BenzaMide Axitinib Impurity a Axitinib-13C-d3Related product price
- Afatinib (BIBW 2992)
$24-2658.8 - Crizotinib
$5-1963.5 - Sunitinib Malate
$6-1593.9
Suppliers and manufacturers
Shandong Risen-Sun Pharmaceutical Co., Ltd
