Anifostine trihydrate
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- $6 - $2000
- Product name: Anifostine trihydrate
- CAS: 112901-68-5
- MF: C5H17N2O4PS
- MW: 232.23
- EINECS:
- MDL Number:MFCD00233058
- Synonyms:Amifostine (150 mg);Anifostine trihydrate;Ethanethiol,2-[(3-aMinopropyl)aMino]-, 1-(dihydrogen phosphate), hydrate (1:3);Amifostine trihydrate, >=98%;Aminopropylamino)ethylsulfanylphosphonic acid trihydrate;S-2-(3-AMINOPROPYLAMINO)ETHYL O,O-DIHYDROGEN PHOSPHOROTHIOATE;WR2721;Amifostinetrihydrateormonohydrate
26 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- Arctom
- AvaChem
- Cayman Chemical
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 5MG
- 10mg
- 50mg
- 100mg
- 150mg
- 250mg
- 300MG
- 500mg
- 1g
- 2.5g
- 5g
- ManufacturerAK Scientific
- Product number2141AH
- Product description2-(3-Aminopropylamino)ethylsulfanylphosphonicacidtrihydrate
- Packaging10mg
- Price$92
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA210496
- Product descriptionAmifostine trihydrate 97%
- Packaging50mg
- Price$6
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA210496
- Product descriptionAmifostine trihydrate 97%
- Packaging100mg
- Price$8
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA210496
- Product descriptionAmifostine trihydrate 97%
- Packaging250mg
- Price$13
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA210496
- Product descriptionAmifostine trihydrate 97%
- Packaging1g
- Price$37
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA210496
- Product descriptionAmifostine trihydrate 97%
- Packaging5g
- Price$124
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberING0008290
- Product description2-(3-AMINOPROPYLAMINO)ETHYLSULFANYLPHOSPHONIC ACID TRIHYDRATE 95.00%
- Packaging5MG
- Price$498.86
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS479328
- Product descriptionAmifostine trihydrate 97%
- Packaging10mg
- Price$24
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS479328
- Product descriptionAmifostine trihydrate 97%
- Packaging50mg
- Price$51
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS479328
- Product descriptionAmifostine trihydrate 97%
- Packaging100mg
- Price$62
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS479328
- Product descriptionAmifostine trihydrate 97%
- Packaging250mg
- Price$108
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS479328
- Product descriptionAmifostine trihydrate 97%
- Packaging1g
- Price$266
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2611H
- Product descriptionAmifostine Trihydrate
- Packaging100mg
- Price$129
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2611H
- Product descriptionAmifostine Trihydrate
- Packaging1g
- Price$259
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2611H
- Product descriptionAmifostine Trihydrate
- Packaging5g
- Price$790
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14398
- Product descriptionAmifostine (hydrate) ≥95%
- Packaging50mg
- Price$62
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2141AH | 2-(3-Aminopropylamino)ethylsulfanylphosphonicacidtrihydrate | 10mg | $92 | 2021-12-16 | Buy |
| Ambeed | A210496 | Amifostine trihydrate 97% | 50mg | $6 | 2021-12-16 | Buy |
| Ambeed | A210496 | Amifostine trihydrate 97% | 100mg | $8 | 2021-12-16 | Buy |
| Ambeed | A210496 | Amifostine trihydrate 97% | 250mg | $13 | 2021-12-16 | Buy |
| Ambeed | A210496 | Amifostine trihydrate 97% | 1g | $37 | 2021-12-16 | Buy |
| Ambeed | A210496 | Amifostine trihydrate 97% | 5g | $124 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | ING0008290 | 2-(3-AMINOPROPYLAMINO)ETHYLSULFANYLPHOSPHONIC ACID TRIHYDRATE 95.00% | 5MG | $498.86 | 2021-12-16 | Buy |
| Arctom | AS479328 | Amifostine trihydrate 97% | 10mg | $24 | 2021-12-16 | Buy |
| Arctom | AS479328 | Amifostine trihydrate 97% | 50mg | $51 | 2021-12-16 | Buy |
| Arctom | AS479328 | Amifostine trihydrate 97% | 100mg | $62 | 2021-12-16 | Buy |
| Arctom | AS479328 | Amifostine trihydrate 97% | 250mg | $108 | 2021-12-16 | Buy |
| Arctom | AS479328 | Amifostine trihydrate 97% | 1g | $266 | 2021-12-16 | Buy |
| AvaChem | 2611H | Amifostine Trihydrate | 100mg | $129 | 2021-12-16 | Buy |
| AvaChem | 2611H | Amifostine Trihydrate | 1g | $259 | 2021-12-16 | Buy |
| AvaChem | 2611H | Amifostine Trihydrate | 5g | $790 | 2021-12-16 | Buy |
| Cayman Chemical | 14398 | Amifostine (hydrate) ≥95% | 50mg | $62 | 2024-03-01 | Buy |
Properties
storage temp. :2-8°C
solubility :PBS (pH 7.2): 5 mg/ml
form :powder
pka :pKa1 <2.0; pKa2 4.2; pKa3 9.0; pKa4 11.7(at 25℃)
color :White to off-white
InChIKey :JKOQGQFVAUAYPM-UHFFFAOYSA-N
CAS DataBase Reference :112901-68-5(CAS DataBase Reference)
solubility :PBS (pH 7.2): 5 mg/ml
form :powder
pka :pKa1 <2.0; pKa2 4.2; pKa3 9.0; pKa4 11.7(at 25℃)
color :White to off-white
InChIKey :JKOQGQFVAUAYPM-UHFFFAOYSA-N
CAS DataBase Reference :112901-68-5(CAS DataBase Reference)
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | ||||||||||||||
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Description
Amifostine is a prodrug that through dephosphorylation by alkaline phosphatase is converted to an active thiol, WR 1065 that has free radical scavenging, DNA protective, and hypoxia inducing activities. Because of the differential expression of alkaline phosphatase in normal versus neoplastic tissues, the cytoprotection conferred by amifostine is selective, enabling as much as 100-fold greater accumulation of WR 1065 in normal tissues than in tumor cells. Amifostine has been used to reduce toxicity in normal tissues exposed to radiation or chemotherapeutic agents. In mouse fibroblasts and various cancer cells, amifostine (IC50 = 4 mM) has been shown to activate p53 protein, to induce the expression of the cyclin-dependent kinase inhibitor p21, and to arrest cells at the G1/S transition through a p53-dependent mechanism.More related product prices
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