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ChemicalBook >> CAS DataBase List >> Docetaxel

Docetaxel

Docetaxel price.
  • $32 - $1750
  • Product name: Docetaxel
  • CAS: 114977-28-5
  • MF: C43H53NO14
  • MW: 807.88
  • EINECS:601-339-2
  • MDL Number:MFCD00871399
  • Synonyms:Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-;Docetaxel N-debenzoyl-N-tert-butoxycarbonyl-10-deacetyl taxol;Taxotere anhydrous;n-debenzoyl-n-tert-butoxycarbonyl-10-deacetyl taxol;)benz(1,2-b)oxet-9-ylester,(2ar-(2a-alpha,4-beta,4a-beta,6-beta,9-alpha(alph ;Benzenepropanoic acid, b-[[(1,1-dimethylethoxy)carbonyl]amino]-a-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trih ydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (aR,bS)-;DOCETAXEL ANHYDROUS 99.5%;Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2aα,4β,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,12bα]]-
69 prices
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Brand
  • Adipogen Life Sciences
  • AHH
  • AK Scientific
  • Alfa Aesar
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • AstaTech
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
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  • 20mg
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  • 0.1g
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  • y0001466
  • 25g
  • 1/ G
  • 5/ G
  • 10/ G
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-D0371-M025
  • Product descriptionDocetaxel ≥97%(HPLC)
  • Packaging25mg
  • Price$106
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberAPI-1261
  • Product descriptionDocetaxel 98%
  • Packaging0.1g
  • Price$305
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberG516
  • Product descriptionDocetaxel(Taxotere)
  • Packaging100mg
  • Price$67
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ95760
  • Product descriptionDocetaxel(Taxotere)
  • Packaging500mg
  • Price$147
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ95760
  • Product descriptionDocetaxel(Taxotere)
  • Packaging1g
  • Price$226
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60174
  • Product descriptionDocetaxel, 99%
  • Packaging100mg
  • Price$185
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60174
  • Product descriptionDocetaxel, 99%
  • Packaging500mg
  • Price$494
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60174
  • Product descriptionDocetaxel, 99%
  • Packaging1g
  • Price$898
  • Updated2024-03-01
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4394
  • Product descriptionDocetaxel
  • Packaging100mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBID2710
  • Product descriptionDocetaxel >99%
  • Packaging100mg
  • Price$129
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBID2710
  • Product descriptionDocetaxel >99%
  • Packaging250mg
  • Price$216
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBID2710
  • Product descriptionDocetaxel >99%
  • Packaging1g
  • Price$473
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN98517
  • Product descriptionDocetaxel
  • Packaging20mg
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerAstaTech
  • Product number45008
  • Product descriptionDOCETAXEL 97%
  • Packaging1/ G
  • Price$155
  • Updated2021-12-16
  • Buy
  • ManufacturerAstaTech
  • Product number45008
  • Product descriptionDOCETAXEL 97%
  • Packaging5/ G
  • Price$466
  • Updated2021-12-16
  • Buy
  • ManufacturerAstaTech
  • Product number45008
  • Product descriptionDOCETAXEL 97%
  • Packaging10/ G
  • Price$699
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences CDX-D0371-M025 Docetaxel ≥97%(HPLC) 25mg $106 2021-12-16 Buy
AHH API-1261 Docetaxel 98% 0.1g $305 2021-12-16 Buy
AK Scientific G516 Docetaxel(Taxotere) 100mg $67 2021-12-16 Buy
AK Scientific J95760 Docetaxel(Taxotere) 500mg $147 2021-12-16 Buy
AK Scientific J95760 Docetaxel(Taxotere) 1g $226 2021-12-16 Buy
Alfa Aesar J60174 Docetaxel, 99% 100mg $185 2024-03-01 Buy
Alfa Aesar J60174 Docetaxel, 99% 500mg $494 2024-03-01 Buy
Alfa Aesar J60174 Docetaxel, 99% 1g $898 2024-03-01 Buy
ApexBio Technology A4394 Docetaxel 100mg $60 2021-12-16 Buy
Apolloscientific BID2710 Docetaxel >99% 100mg $129 2021-12-16 Buy
Apolloscientific BID2710 Docetaxel >99% 250mg $216 2021-12-16 Buy
Apolloscientific BID2710 Docetaxel >99% 1g $473 2021-12-16 Buy
Arctom CFN98517 Docetaxel 20mg $40 2021-12-16 Buy
AstaTech 45008 DOCETAXEL 97% 1/ G $155 2021-12-16 Buy
AstaTech 45008 DOCETAXEL 97% 5/ G $466 2021-12-16 Buy
AstaTech 45008 DOCETAXEL 97% 10/ G $699 2021-12-16 Buy

Properties

Melting point :186-192 °C (dec.)
alpha :-36 º (c=0.74,EtOH)
Boiling point :900.5±65.0 °C(Predicted)
Density :1.38
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Practically insoluble in water, freely soluble in anhydrous ethanol, soluble in methylene chloride.
form :Solid
pka :11.20±0.46(Predicted)
color :White
Water Solubility :Soluble in dimethyl sulfoxide and ethanol. Insoluble in water.
Merck :14,3397
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey :BEDLLNJKXXVTSX-LWWLJZAUSA-N
LogP :2.456 (est)
CAS DataBase Reference :114977-28-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H362 May cause harm to breast-fed children Reproductive toxicity, effects on or via lactation Additional category P201, P260, P263, P264, P270,P308+P313
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P263 Avoid contact during pregnancy/while nursing.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Docetaxel is a semisynthetic analog of taxol that inhibits microtubule disassembly (IC50 = 0.2 μM) and inhibits cell replication (IC50 = 0.13 μM). It has proven more effective than taxol in preventing the proliferation of cancer cells. Docetaxel has applications in breast cancer and hormone-refractory prostate cancer. This product is intended for research applications.

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