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1,4-?????-2,6-???-4-(3-?????)-3,5-???????????(1-????)????

1,4-?????-2,6-???-4-(3-?????)-3,5-???????????(1-????)????
1,4-?????-2,6-???-4-(3-?????)-3,5-???????????(1-????)???? ??? ???
?? ??:
21881-78-7
???:
1,4-?????-2,6-???-4-(3-?????)-3,5-???????????(1-????)????
???(??):
1,4-?????-2,6-???-4-(3-?????)-3,5-???????????(1-????)????
???:
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester
???(??):
Nimodipine EP Imp B;Nimodipine Impurity 2;Nilvadipine Impurity D;Nilvadipine Impurity 4;Nitrendipine Impurity 8;Nimodipine EP Impurity B;Nitrendipine Impurity1224;Nimodipine Impurity B Control;Bis(1-methylethyl) 2,6-Dimethyl-4-(;Nimodipine EP Impurity B(Nitrendipine Impurity1224)
CBNumber:
CB82717263
???:
C21H26N2O6
??? ??:
402.44
MOL ??:
21881-78-7.mol
MSDS ??:
SDS

1,4-?????-2,6-???-4-(3-?????)-3,5-???????????(1-????)???? ??

???
123-125℃ (ethanol )
?? ?
512.1±50.0 °C(Predicted)
??
1.186±0.06 g/cm3(Predicted)
?? ??
Hygroscopic, -20°C Freezer, Under inert atmosphere
???
?????(?? ???), ???(?? ???)
??? ??
??
??? ??
??? ??
?? ?? (pKa)
2.94±0.70(Predicted)
??
?????
???
???

??

1,4-?????-2,6-???-4-(3-?????)-3,5-???????????(1-????)???? C??? ??, ??, ??

??

3-Des(2-methoxyethyl) 3-(1-Methylethyl) Ester Nimodipine (Nimodipine EP Impurity B) can be used in synthetic preparation of dihydropyridinedicarboxylic acid esters by methylimidazolium trifluoroacetate-catalyzed Hantzsch cyclocondensation reaction of oxo-carboxylic acid esters with aldehydes and ammonium acetate. It can also be used as an analyte for analytical study in developing and optimizing a validated isocratic reversed-phase high-performance liquid chromatograhy separation of nimodipine and impurities in tablets using experimental. design methodology. It is an impurity of the drug Nimodipine (N478200).

1,4-?????-2,6-???-4-(3-?????)-3,5-???????????(1-????)???? ?? ?? ? ???

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1,4-?????-2,6-???-4-(3-?????)-3,5-???????????(1-????)???? ?? ??

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