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1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester Struktur
21881-78-7
CAS-Nr.
21881-78-7
Englisch Name:
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester
Synonyma:
Nimodipine EP Imp B;Nimodipine Impurity 2;Nilvadipine Impurity D;Nilvadipine Impurity 4;Nitrendipine Impurity 8;Nimodipine EP Impurity B;Nitrendipine Impurity1224;Nimodipine Impurity B Control;Bis(1-methylethyl) 2,6-Dimethyl-4-(;Nimodipine EP Impurity B(Nitrendipine Impurity1224)
CBNumber:
CB82717263
Summenformel:
C21H26N2O6
Molgewicht:
402.44
MOL-Datei:
21881-78-7.mol

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester Eigenschaften

Schmelzpunkt:
123-125℃ (ethanol )
Siedepunkt:
512.1±50.0 °C(Predicted)
Dichte
1.186±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
L?slichkeit
Chloroform (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
pka
2.94±0.70(Predicted)
Farbe
Pale Beige
Stabilit?t:
Hygroscopic

Sicherheit

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

3-Des(2-methoxyethyl) 3-(1-Methylethyl) Ester Nimodipine (Nimodipine EP Impurity B) can be used in synthetic preparation of dihydropyridinedicarboxylic acid esters by methylimidazolium trifluoroacetate-catalyzed Hantzsch cyclocondensation reaction of oxo-carboxylic acid esters with aldehydes and ammonium acetate. It can also be used as an analyte for analytical study in developing and optimizing a validated isocratic reversed-phase high-performance liquid chromatograhy separation of nimodipine and impurities in tablets using experimental. design methodology. It is an impurity of the drug Nimodipine (N478200).

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 64)Lieferanten
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21881-78-7()Verwandte Suche:


  • 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester
  • Nimodipine EP Impurity B
  • (RS)-Di-iso-propyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate
  • Bis(1-methylethyl) 2,6-Dimethyl-4-(
  • Nimodipine Impurity B Control
  • 3,5-diisopropyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
  • Nimodipine EP Imp B
  • Nimodipine Impurity 2
  • 3-Des(2-methoxyethyl) 3-(1-Methylethyl) Ester Nimodipine
  • Bis(1-methylethyl) 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
  • Nitrendipine Impurity1224
  • diisopropyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
  • Nitrendipine Impurity 8
  • 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3,5-bis(1-methylethyl) ester
  • Nilvadipine Impurity D
  • Diisopropyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate (Nimodipine Impurity)
  • Nimodipine EP Impurity B(Nitrendipine Impurity1224)
  • Nilvadipine Impurity 4
  • 21881-78-7
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