Fexofenadine
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Fexofenadine ??
- ???
- 218-220°C
- ?? ?
- 697.3±55.0 °C(Predicted)
- ??
- 1.171±0.06 g/cm3(Predicted)
- ?? ??
- Sealed in dry,Store in freezer, under -20°C
- ???
- ???(?? ??, ??? ??)
- ??? ??
- ??
- ??? ??
- ??? ??
- ?? ?? (pKa)
- 4.43±0.10(Predicted)
- ??
- ???? ?????
- BCS Class
- 1,3
- LogP
- 2.81
- CAS ??????
- 83799-24-0(CAS DataBase Reference)
??
| ?? ?? ??? | 83799-24-0(Hazardous Substances Data) |
|---|
Fexofenadine C??? ??, ??, ??
??
Fexofenadine, the carboxylic acid metabolite of terfenadine, is widely available. It accounts for the antihistaminic properties of terfenadine, which is very rapidly metabolized via CYP3A4-catalyzed processes. Members of the organic anion transporter protein family and the drug efflux transporter P-glycoprotein are involved in the disposition of fexofenadine. Fexofenadine does not have the antiarrhythmic side effects of terfenadine.??? ??
White Powder??
A metabolite of of terfenadine, a H1-Histamine receptor antagonist??
ChEBI: A piperidine-based anti-histamine compound.Fexofenadine ?? ?? ? ???
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Trimethoxychlorosilane
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??-[4-(1,1-?????)??]-4-(??????????)-1-??????? ; ?????, ???
4-???????
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Fexofenadine ?? ??
???( 216)?? ??
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|---|---|---|---|---|---|
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