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2-??????? ?

2-??????? ?
2-??????? ? ??? ???
?? ??:
826-55-1
???:
2-??????? ?
???(??):
2-????????;2-??-2-???????
???:
2-Phenylisobutyric acid
???(??):
2-methyl-2-phenylpropanoic acid;TH 4161;NSC 28952;NSC 29095;α, α-diMethyl acid;RARECHEM AL BO 1659;Phenylisobutyric Aci;2- phenylisobutyrate;2-Phenylisobutyrsure;Bilastine Impurity 48
CBNumber:
CB8424536
???:
C10H12O2
??? ??:
164.2
MOL ??:
826-55-1.mol
MSDS ??:
SDS

2-??????? ? ??

???
80-82°C
?? ?
146.5°C
??
1.089±0.06 g/cm3(Predicted)
???
146.5°C
?? ??
Sealed in dry,Room Temperature
???
?????(?? ???), ???(?? ???)
?? ?? (pKa)
4.39±0.10(Predicted)
??? ??
?? ??
??
???
???
?? ???.
LogP
2.3 at 20℃
CAS ??????
826-55-1(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ???? ?? 36/37/38-36/38
????? 26-36/37/39
HS ?? 2916399090
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P321 (…) ??? ???.
P332+P313 ?? ??? ??? ???? ??· ??? ????.
P337+P313 ?? ?? ??? ???? ???? ??· ??? ????.
NFPA 704
0
2 0

2-??????? ? C??? ??, ??, ??

??

2-Methyl-2-phenylpropionic acid is used in the synthesis of Fexofenadine hydrochloride

Synthesis Reference(s)

The Journal of Organic Chemistry, 23, p. 1636, 1958 DOI: 10.1021/jo01105a014

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??-?????????? Benzene, (1-bromo-1-methylethyl)- ALPHA,ALPHA-DIMETHYLBENZYL PHENYL SULFIDE ????????? 2-??-2-???????? ??2,2-?????????? α,α-???-?? ???? ?????? ?? ?????? ??-?? ????

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