DIETHYL BROMOPHOSPHATE
- CAS No.
- 51761-27-4
- Chemical Name:
- DIETHYL BROMOPHOSPHATE
- Synonyms
- DIETHYL BROMOPHOSPHATE;diethyl phosphorobromidate;Bromidophosphoric acid diethyl ester;Phosphorobromidic acid, diethyl ester
- CBNumber:
- CB8511788
- Molecular Formula:
- C4H10BrO3P
- Molecular Weight:
- 217
- MDL Number:
- MFCD01074583
- MOL File:
- 51761-27-4.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H331-H314-H301-H311 |
| Precautionary statements | P261-P271-P304+P340-P311-P321-P403+P233-P405-P501-P260-P264-P280-P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P321-P305+P351+P338-P405-P501-P264-P270-P301+P310-P321-P330-P405-P501-P280-P302+P352-P312-P322-P361-P363-P405-P501 |
DIETHYL BROMOPHOSPHATE Chemical Properties,Uses,Production
Uses
Used in β-lactam formation; peptide synthesis; formation of trifluoroacetyl bromide.
Preparation
Diethyl phosphorobromidate is prepared in good yield from the reaction between N-Bromosuccinimide and diethyl hydrogen phosphite,1 or from the bromination of Triethyl Phosphite with Bromine at -30 °C to -25 °C.2 It can also be prepared in almost quantitative yield by reacting diethyl hydrogen phosphite with Chlorotrimethylsilane followed by bromine at -78 °C.
storage
Highly toxic, corrosive, and a lachrymator. It should be used in a fume hood. It is highly moisture sensitive and undergoes thermal decomposition. It generates toxic byproducts when decomposition occurs. Should be stored under nitrogen in a cool dry place.
DIETHYL BROMOPHOSPHATE Preparation Products And Raw materials
Raw materials
Preparation Products
DIETHYL BROMOPHOSPHATE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong WorldSun Biological Technology Co., Ltd. | 0531-88723173 18596073690 | 1047208234@qq.com | China | 5278 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | info@synzest.com | China | 9286 | 58 |
| Zhengzhou Alpha Chemical Co. LTD | 0371-0371-53732842 13383863444 | 3002612166@qq.com | China | 10073 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 18351873721 | helen.zhang@synzest.com | China | 8295 | 58 |