L-2-Hydroxy-2-phenylessigsure
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- CAS-Nr.
- 611-71-2
- Bezeichnung:
- L-2-Hydroxy-2-phenylessigsure
- Englisch Name:
- Mandelic acid
- Synonyma:
- D-MANDELIC ACID;(R)-(-)-MANDELIC ACID;(R)-2-HYDROXY-2-PHENYLACETIC ACID;(R)-MANDELIC ACID;2-Hydroxy-2-phenylacetic acid;(R)-(-)-2-MANDELIC ACID;(-)-MANDELIC ACID;D-(-)-MANDELIC ACID;(-)-D-MANDELIC ACID;D-ALPHA-HYDROXYPHENYLACETIC ACID
- CBNumber:
- CB9411418
- Summenformel:
- C8H8O3
- Molgewicht:
- 152.15
- MOL-Datei:
- 611-71-2.mol
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L-2-Hydroxy-2-phenylessigsure Eigenschaften
- Schmelzpunkt:
- 131-133 °C(lit.)
- Siedepunkt:
- 214.6°C (rough estimate)
- alpha
- -150 º (c=2.5, H2O)
- Dichte
- 1.1677 (rough estimate)
- Brechungsindex
- -153.5 ° (C=1, H2O)
- Flammpunkt:
- >190℃
- storage temp.
- Store below +30°C.
- L?slichkeit
- 109.8g/l soluble
- Aggregatzustand
- Crystalline Powder, Crystals or Flakes
- pka
- 3.37(at 25℃)
- Farbe
- White to slightly yellow-beige
- PH
- 3.34(1 mM solution);2.75(10 mM solution);2.22(100 mM solution);
- Optische Aktivit?t
- [α]25/D 151°, c = 1 in ethanol
- Wasserl?slichkeit
- It is partly soluble in water, freely soluble in isopropyl and ethyl alcohol.
- Sensitive
- Light Sensitive
- BRN
- 2691094
- Stabilit?t:
- Stable, but light sensitive. Combustible. Incompatible with strong bases, strong oxidizing agents.
- InChIKey
- IWYDHOAUDWTVEP-SSDOTTSWSA-N
- LogP
- 0.550 (est)
- CAS Datenbank
- 611-71-2(CAS DataBase Reference)
- EPA chemische Informationen
- Benzeneacetic acid, .alpha.-hydroxy-, (.alpha.R)- (611-71-2)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xi |
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| R-S?tze: |
41-36/37/38 |
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| S-S?tze: |
22-24/25-36-26-39-37/39 |
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| WGK Germany |
1 |
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| Hazard Note |
Irritant/Light Sensitive |
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| TSCA |
Yes |
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| HS Code |
29181980 |
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| Toxizit?t |
LD50 orally in Rabbit: 5000 mg/kg |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H318 |
Verursacht schwere Augensch?den. |
Schwere Augensch?digung |
Kategorie 1 |
Achtung |
![GHS hazard pictograms]() src="/GHS05.jpg" width="20" height="20" /> |
P280, P305+P351+P338, P310 |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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L-2-Hydroxy-2-phenylessigsure Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R41:Gefahr ernster Augensch?den.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
white to light yellow crystal powde
Verwenden
(R)-(-)-Mandelic acid, is used as a antiseptic ingredient particularly against urinary tract infections.Mandelic acid and its derivatives are used to apply the dual activities as an antibacterial agent and as an antiaging agent. It is used as an intermediate for the synthesis of target molecules for other applications.
Allgemeine Beschreibung
(
R)-(-)-Mandelic acid, a chiral resolving agent, is also used as a building block to synthesize pharmaceutical drugs such as penicillin and cephalosporin. It can be synthesized from (
R,
S)-mandelonitrile with high yield and enantioselectivity using nitrilase enzyme.
l?uterung methode
Purify the mandelic acids by recrystallisation from H2O, *C6H6 or CHCl3. [Roger J Chem Soc 2168 1932,Jamison & Turner J Chem Soc 611 1942.] They have solubilities in H2O of ca 11% at 25o. [Banks & Davies J Chem Soc 73 1938.] The S-benzylisothiuronium salts has m 180o (from H2O) and [] D 25 (+) and (-) 57o (c20, EtOH) [El Masri et al. Biochem J 68 199 1958]. [Beilstein 10 IV 564.]
L-2-Hydroxy-2-phenylessigsure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
1H-Azepine-4-carboxylicacid,hexahydro-,methylester,(4R)-(9CI)
(R)-3-Amino-1-(3-(Trifluoromethyl)-5,6-Dihydro-[1,2,4] Triazolo[4,3-A]Pyrazin-7(8H)-Yl)-4-(2,4,5-Trifluorophenyl) Butan-1-One Mandelate(Sgn06M)
(R)-5-Phenyl-1,3-dioxolan-2,4-dion
(R)-2-Hydroxy-2-phenylacetohydrazide
(R)-2-tert-butyl-3-Methyl-4-oxoiMidazolidin-1-iuM (R)-2-hydroxy-2-phenylacetate
(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-Hydroxy(phenyl)ethanoate
L-2-Hydroxy-2-phenylessigsure Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 751)Lieferanten
| Firmenname |
Telefon |
E-Mail |
Land |
Produktkatalog |
Edge Rate |
|
Hebei Weibang Biotechnology Co., Ltd
|
+8615531157085
|
abby@weibangbio.com |
China |
8810 |
58 |
|
Hebei Mojin Biotechnology Co., Ltd
|
+86 13288715578 +8613288715578
|
sales@hbmojin.com |
China |
12835 |
58 |
|
Hebei Yanxi Chemical Co., Ltd.
|
+8617531190177
|
peter@yan-xi.com |
China |
5857 |
58 |
|
Hebei Chuanghai Biotechnology Co,.LTD
|
+86-13131129325
|
sales1@chuanghaibio.com |
China |
5889 |
58 |
|
Firsky International Trade (Wuhan) Co., Ltd
|
+8615387054039
|
admin@firsky-cn.com |
China |
427 |
58 |
|
Anhui Ruihan Technology Co., Ltd
|
+8617756083858
|
daisy@anhuiruihan.com |
China |
973 |
58 |
|
Hebei Jingbo New Material Technology Co., Ltd
|
+8619931165850
|
hbjbtech@163.com |
China |
1000 |
58 |
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Chongqing Zhihe Biopharmaceutical Co., Ltd.
|
+86-18580541567; +8618580541567
|
sales@zhswyy.com |
China |
301 |
58 |
|
Hebei Saisier Technology Co., LTD
|
+86-18400010335 +86-18034520335
|
admin@hbsaisier.cn |
China |
1015 |
58 |
|
BINBO BIOLOGICAL CO.,LTD
|
+8618629063126
|
info@binbobiological.com |
China |
423 |
58 |
611-71-2(L-2-Hydroxy-2-phenylessigsure)Verwandte Suche:
- (R)-(-)-AMYGDALIC ACID
- (R)-ALPHA-HYDROXYPHENYLACETIC ACID
- R-(-)-ALPHA-HYDROXYPHENYLACETIC ACID
- D-A-HYDROXYPHENYLACETIC ACID
- D-2-HYDROXY-PHENYLACETIC ACID
- D-(-)-AMYGDALIC ACID
- D-AMYGDALIC ACID
- D-PHENYLGLYCOLIC ACID
- L-2-hydroxy-2-phenylacetic acid
- D(-)-MANDELIC ACID FOR RESOLUTION &
- (R)-(-)-MANDELIC ACID, 99+%
- (R)-(-)-MANDELIC ACID, 98% (99% EE/GLC)
- (R)-(-)-MANDELIC ACID 99%
- D-(-)-α-Hydroxybenzeneacetic acid
- ALPHAR-HYDROXY-BENZENEACETIC ACID
- D-Mandelic acid or R-(-)Mandelic acid
- Benzeneacetic acid, .alpha.-hydroxy-, (.alpha.R)-
- (r)-(-)-à-hydroxyphenylacetic acid
- D-mandelic acid(R-mandelic acid)
- (R)-alpha-Hydrophenylacetic acid
- D-(-)-Mandelic acid 98%
- L-2-Hydroxy-2-phenylessigsure
- D-minus-mandelic acid sigma grade
- [R,(-)]-α-Hydroxybenzeneacetic acid
- D-()-Mandelic acid,(R)-α-Hydroxyphenylacetic acid
- (R)-(-)-Mandelic acid, ChiPros\(tm, 99+% ee 99+%
- )-Mandel
- (R)-(-)-alpha-Hydroxyphenylacetic acid, (2R)-(-)-Hydroxy(phenyl)ethanoic acid, D-(-)-Phenylglycolic acid
- (R)-Alfa-hydroxyphenylacetic acid
- (R)-()-Mandel
- (R)-(-)-Mandelic acid, 99% 25GR
- (R)-(-)-Mandelic acid, 98% e.e.
- (R)-(-)-MANDELIC ACID FOR RESOLUTION OF
- (R)-2-Phenylglycolic acid
- (R)-alpha-Hydroxy-benzeneacetic acid
- Sertraline EP IMpurity E
- (R)-(-)-alpha-Hydroxyphenylacetic acid, (2R)-(-)-2-Hydroxy-2-phenylethanoic acid, D-(-)-Phenylglycolic acid
- (R)-(-)-Mandelic acid, ChiPros 99+%, ee 99+%
- D-MANDELIC ACID extrapure
- (2R)-2-Hydroxy-2-phenylacetic acid
- (R)-a-Hydroxybenzeneacetic acid
- (R)-a-Hydroxyphenylacetic acid
- D-2-Phenylglycolic acid
- (R)-(-)-MANDELIC ACID: CHIPROS 99%, EE 99%
- 2-Phenylglycolic acid
- a-Hydroxy-benzeneacetic acid
- alpha-Hydroxyphenylacetic acid
- Hydroxy(phenyl)acetic acid
- R-Mandelic acid D-Mandelic acid
- (R)-mandelate
- Benzeneaceticacid, a-hydroxy-, (aR)-
- (R)-(-)-Mandelic acid ReagentPlus(R), >=99%
- Sertraline impurity E
- (R)-(-)-Mandelic acid Vetec(TM) reagent grade, 98%
- (R)-(-)-mandelic
- (R)-Hydroxyphenylaceticacid
- (R)-Mandelic Acid,99%e.e.
- RARECHEM AL BO 1446
