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Dinatrium-5,5'-(2-(1,3-dihydro-3-oxo-2H-indazol-2-yliden)-1,2-dihydro-3H-indol-3-on)disulfonat

Indigo Carmine Struktur
860-22-0
CAS-Nr.
860-22-0
Bezeichnung:
Dinatrium-5,5'-(2-(1,3-dihydro-3-oxo-2H-indazol-2-yliden)-1,2-dihydro-3H-indol-3-on)disulfonat
Englisch Name:
Indigo Carmine
Synonyma:
INDIGOTINE;CI 73015;Indigo Carmine,pure,certified;E132;73015;Was35;l-blau2;murabba;1311blue;Greell S
CBNumber:
CB8231484
Summenformel:
C16H11N2NaO8S2
Molgewicht:
446.38
MOL-Datei:
860-22-0.mol

Dinatrium-5,5'-(2-(1,3-dihydro-3-oxo-2H-indazol-2-yliden)-1,2-dihydro-3H-indol-3-on)disulfonat Eigenschaften

Schmelzpunkt:
>300°C
Dichte
1.01 g/mL at 20 °C
Brechungsindex
n20/D 1.335
storage temp. 
room temp
L?slichkeit
1g/l
Colour Index 
73015
Aggregatzustand
Powder/Solid
Farbe
Very dark blue to purple
PH
7 (10g/l, H2O, 20℃)
S?ure-Base-Indikators(pH-Indikatoren)
11.5(blue)-14.0(yellow)
Geruch (Odor)
Light odour
Wasserl?slichkeit
1 g/100 mL (25 ºC)
Sensitive 
Light Sensitive
maximale Wellenl?nge (λmax)
608nm
Merck 
14,4944
BRN 
4103904
Stabilit?t:
Stable. Incompatible with strong oxidizing agents.
Biologische Anwendungen
Detecting microorganisms; treating amyloidosis,testicular cancer; medical devices; drug delivery system
Major Application
Display device, sensor, chemical-mechanical polishing, batteries, photographic materials, thermoplastics, inks, highlighters, detergents, disinfectants, rodenticide, colored bubbles, hair dyes, cosmetics, food, determine bacterial growth, antiischemic Magents, antiseptic, antitumor agents, Alzheimer’s disease, psychoactive drugs, Tooth whitening
LogP
-3.57
CAS Datenbank
860-22-0(CAS DataBase Reference)
EPA chemische Informationen
C.I. Acid Blue 74 (860-22-0)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn,Xi
R-S?tze: 22-36/37/38
S-S?tze: 22-24/25-36/37/39-27-26
WGK Germany  3
RTECS-Nr. DU3000000
TSCA  Yes
HS Code  32041200
Giftige Stoffe Daten 860-22-0(Hazardous Substances Data)
Toxizit?t LD50 orally in Rabbit: > 2000 mg/kg
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H317 Kann allergische Hautreaktionen verursachen. Sensibilisierung der Haut Kategorie 1A Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Sicherheit
P261 Einatmen von Staub vermeiden.
P272 Kontaminierte Arbeitskleidung nicht au?erhalb des Arbeitsplatzes tragen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P302+P352 BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen.
P333+P313 Bei Hautreizung oder -ausschlag: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.

Dinatrium-5,5'-(2-(1,3-dihydro-3-oxo-2H-indazol-2-yliden)-1,2-dihydro-3H-indol-3-on)disulfonat Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R22:Gesundheitssch?dlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S27:Beschmutzte, getr?nkte Kleidung sofort ausziehen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Beschreibung

Indigo carmine is indigotindisulfonate sodium, a marker dye used during cystoscopy and ureteral catheterization.
(1) Indigo carmine is also used in endoscopic procedures, lymph node and vessel delineation, and for tumor localization. Indigo carmine is an unapproved drug without FDA approved labeling.
(2) There is no single dye that can replace indigo carmine. Choice of alternative agent will depend on type of procedure and physician discretion, as well as product availability.
Indigo Carmine (IC) is the most common chemical dye for clothes dyeing, which is considered as a refractory molecule since it is required a rather strong chemical treatment for its elimination from the water waste. The presence of this dye in residuals causes notorious change of water color and smell even in very low concentration. Moreover, if some of this water reaches natural streams it can be toxic for aquatic living entities due to the formation of toxic compounds such as aromatic amines.

Chemische Eigenschaften

purple powder

Verwenden

Indigo Carmine (FD&C Blue #2) is a colorant. It has poor ph stability in that after 1 week at ph 3 and 5 it will appreciably fade, at ph 7 considerably fade, and at ph 8 fade completely. It is the least soluble of all food colors, with a solubility of 1.6 g in 100 ml of water at 25°c. Complete fading occurs in alkalis such as 10% sodium carbonate and 10% sodium hydroxide, with fading also occurring in 10% sugar systems. It has very poor light stability and oxidation stability, and moderate stability to heat; it has a deep blue hue with poor tinctorial strength. It is the only food color that has good resistance to reducing agents, but has very poor compatibility with food components. The major use is in pet food, but it is also used in candies, confections, and baked goods. The common name is indigotine.

synthetische

3H-indol-3-one,2-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,2-dihydro?with strong sulfuric acid or trace fuming sulfuric acid products.

Definition

ChEBI: An organic sodium salt resulting from the formal condensation of indigo carmine (acid form) with two equivalents of sodium hydroxide. It is an indicator at pH 11.5-14, changing from blue to yellow.

Allgemeine Beschreibung

Indigo to dark blue powder.

Air & Water Reaktionen

Water soluble.

Reaktivit?t anzeigen

Sensitive to light. Very sensitive to oxidizing agents. Color is readily discharged by nitric acid, chlorates, etc. Color of aqueous solutions fades on standing.

Brandgefahr

Flash point data for Acid Blue 74 is not available, but Acid Blue 74 is probably combustible.

l?uterung methode

Its solubility in H2O is 1g/100mL at 25o. It has been purified by dissolving in H2O, filtering and adding EtOH to cause the salt to separate. Wash the solid with EtOH, Et2O and dry in vacuo. [V.rlander & Schubert Chem Ber 34 1860 1901, UV: Smit et al. Anal Chem 27 1159 1955, Preisler et al. J Am Chem Soc 81 1991 1959, Beilstein 25 IV 1975.]

Einzelnachweise

American Society of Health-system Pharmacist.
Journal of Environmental Protection, 2016, 7, 1693-1706

Dinatrium-5,5'-(2-(1,3-dihydro-3-oxo-2H-indazol-2-yliden)-1,2-dihydro-3H-indol-3-on)disulfonat Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Dinatrium-5,5'-(2-(1,3-dihydro-3-oxo-2H-indazol-2-yliden)-1,2-dihydro-3H-indol-3-on)disulfonat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 547)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325
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Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
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+86-0551-65418679 +8618949832763
info@tnjchem.com China 2986 55
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29880 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28172 58
Standardpharm Co. Ltd.
86-714-3992388
overseasales1@yongstandards.com United States 14332 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873
sales@chemdad.com China 39894 58
Shenyang Simchoice Chemical Co.,Ltd
+86-024-23769576 +86-15040101888
sales@simchoicechem.com China 254 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49374 58
Nanjing Sky Hope Tongyuan Biological Engineering Co., Ltd.
+86-0086-025-69916489 +86-18852044786
tongyuansales@vip.sina.com China 323 58

860-22-0(Dinatrium-5,5'-(2-(1,3-dihydro-3-oxo-2H-indazol-2-yliden)-1,2-dihydro-3H-indol-3-on)disulfonat)Verwandte Suche:


  • indigocarmineconc.fq
  • indigocarminedisodiumsalt
  • indigocarminepowder
  • indigocarminex
  • indigodisulfonate(biologicalstain)
  • indigoextract
  • indigo-karmin
  • indigotin-5,5’-disulfonicaciddisodiumsalt
  • indigotineb
  • indigotinebluelz
  • indigotineconc.powder
  • indigotinedisodiumsalt
  • indigotineextrapurea
  • indigotinei
  • indigotinelake
  • indigotinen
  • indigotini
  • indocarminef
  • intenseblue
  • l-blau2
  • mapleindigocarmine
  • mitsuiindigocarmine
  • modrkysela74
  • modrpigment63
  • modrpotravinarska1
  • murabba
  • sachsischblau
  • san-eiindigocarmine
  • schultznr.1309
  • sodium5,5’-indigotidisulfonate
  • solubleindigo
  • sumitomowoolbluesbc
  • usacertblueno.2
  • INDIGO CARMINE (C.I. 73015) FOR ANALYSIS
  • SodiuM 3,3'-dioxo-[2,2'-biindolinylidene]-5,5'-disulfonate
  • Indigo CarMine, Reagent, ACS
  • Indigo carMine, high purity biological stain
  • Indigotwosulfonic acid sodiuM salt
  • 1H-Indole-5-sulfonicacid, 2-(1,3-dihydro-3-oxo-5-sulfo-2H-indol-2-ylidene)-2,3-dihydro-3-oxo-,sodiuM salt (1:2)
  • Indigotine 0
  • 73015
  • Indigo carmine, Cell Biology and Analysis, Molecular Biology
  • Indigo carmine, Pure
  • FD AND C BLUE NO 2
  • FD AND C BLUE 2
  • FDC BLUE NO 2
  • FOOD BLUE NO 2
  • food blue 1
  • INDIGOTINE 1
  • INDIGOTINE 1A
  • INDIGOTINE DISULFONATE
  • INDIGO CARMINE
  • INDIGO DISULFONATE
  • INDIGO-5,5'-DISULFONIC ACID DISODIUM SALT
  • E132
  • SODIUM INDIGODISULFONATE
  • SODIUM INDIGOTIN DISULFONATE
  • SODIUM COERULINSULFATE
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