5-Ethyldihydro-5-(1-methylbutyl)-2-thioxo-4,6(1H,5H)-pyrimidindion,Mononatrium-Salz Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R25:Giftig beim Verschlucken.

S-S?tze Betriebsanweisung:

S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).

Chemische Eigenschaften

Yellowish-white, hygroscopic powder.

Verwenden

Pentothal (Abbott).

Definition

A rapidly acting barbiturate administered intravenously for general anesthesia and hypnosis. Commonly known as “truth serum.”

Hazard

May cause respiratory failure; use onlywith physician in attendance.

Pharmakokinetik

Thiopental is highly bound to albumin, and free drug availability is increased in hypoproteinaemia. Protein binding is decreased by alkalaemia, hyperventilation and some drugs that occupy the same albumin binding sites, thereby increasing unbound thiopental concentrations. Metabolism occurs predominantly in the liver, and the metabolites are excreted by the kidneys. Only a small proportion is excreted unchanged in the urine. The terminal elimination half-life is approximately 11.5h (longer in the elderly). Elimination after an infusion is a zero-order process with 10%–15% of the remaining drug metabolised each hour. Up to 30% of the original dose may remain in the body at 24h, and a hangover effect is common. Accumulation may result if further doses of thiopental are administered within 1–2 days.

Sicherheitsprofil

Poison by ingestion, intraperitoneal, rectal, subcutaneous, and intravenous routes. Human systemic effects by intraarterial route: acute arterial occlusion; by rectal route: respiratory depression, body temperature decrease, general anesthetic. An experimental teratogen. Experimental reproductive effects. An intravenous anesthetic. When heated to decomposition it emits toxic fumes of NO, and Na2O. See also PENTOTHAL and BARBITURATES

5-Ethyldihydro-5-(1-methylbutyl)-2-thioxo-4,6(1H,5H)-pyrimidindion,Mononatrium-Salz Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

5-Ethyldihydro-5-(1-methylbutyl)-2-thioxo-4,6(1H,5H)-pyrimidindion,Mononatrium-Salz Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
SHANDONG ZHI SHANG CHEMICAL CO.LTD	+86 18953170293	sales@sdzschem.com	China	2930	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
Xi'an MC Biotech, Co., Ltd.	029-89275612 +8618991951683	mcbio_sales@163.com	China	2251	58
Dorne Chemical Technology co. LTD	+86-86-13583358881 +8618560316533	Ethan@dornechem.com	China	3097	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	22784	58
AFINE CHEMICALS LIMITED	+86-0571-85134551	sales@afinechem.com	China	15352	58
GIHI CHEMICALS CO.,LIMITED	+8618058761490	info@gihichemicals.com	China	49978	58

71-73-8(5-Ethyldihydro-5-(1-methylbutyl)-2-thioxo-4,6(1H,5H)-pyrimidindion,Mononatrium-Salz)Verwandte Suche:

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• sodiumthiopental
• sodiumthiopentobarbital
• sodiumthiopentone
• solublethiopentone
• thiomebumalsodium
• thionembutal
• thiopentonesodium
• thiothalsodium
• thipentalsodium
• (+/-)-Thiopental SodiuM Salt-SodiuM Carbonate Mixture (CIII)
• 4,6(1H,5H)-PyriMidinedione,5-ethyldihydro-5-(1-Methylbutyl)-2-thioxo-, sodiuM salt (1:1)
• Thiopental sodium(for injection)
• RS-Thiopental sodium
• Sodium 5-ethyl-5-(a-methylbutyl)-2-thiobarbiturate
• Thionembutal sodium
• Thiopentobarbitone sodium
• Thiopentemal
• 5-Ethyl-5-(1-methylbutyl)-2-thiobarbutyrate sodium
• 5-Ethyl-5-(1-methylbutyl)-2-thiobarbituric acid, Pentothal
• 5-Ethyldihydro-5-(1-methylbutyl)-2-thioxo-4,6(1H,5H)-pyrimidinedione monosodium salt
• Sodium Carbpnate
• 5-Ethyldihydro-5-(1-methylbutyl)-2-thioxo-4,6(1H,5H)-pyrimidinedione sodium salt
• 5-ethyl-5-(1-methylbutyl)-2-thiobarbituricacidmonosodium
• 5-ethyl-5-(1-methylbutyl)-2-thio-barbituricacisodiumsalt
• 6(1h,5h)-pyrimidinedione,5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-monos
• 6(1h,5h)-pyrimidinedione,5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-monosod
• farmotal
• tiopentalsodium
• trapanal
• trapanalsodium
• PENTOTHAL SODIUM-POTASSIUM SALT
• THIOPENTAL SODIUM
• THIOPENTAL SODIUM SALT
• (+/-)-THIOPENTAL SODIUM SALT/SODIUM CARBONATE
• (+/-)-THIOPENTAL SODIUM SALT-SODIUM CARBONATE MIXTURE
• 5-ETHYL-5-(1-METHYLBUTYL)-2-THIOBARBITURIC ACID SODIUM-POTASSIUM SALT
• 5-ETHYL-5-[1-METHYLBUTYL]-2-THIOBARBITURIC ACID SODIUM SALT/SODIUM CARBONATE
• (+,-)-THIOPENTAL SODIUM/SODIUM*CARBONATE --DEA SCHED
• THIOPENTAL SODIUM/SODIUM CARBONATE MIXTU RE >96% INTRAVENOUS AN
• 5-Ethyl-5-[1-methylbutyl]-2-thiobarbituric acid, sodium salt
• Thiopentone, sodium salt
• 4,6(1H,5H)-Pyrimidinedione, 5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-, monosodium salt
• 4,6(1H,5H)-Pyrimidinedione, 5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-, monosodium salt (9CI)
• Barbituric acid, 5-ethyl-5-(1-methylbutyl)-2-thio-, sodium deriv. (7CI)
• Barbituric acid, 5-ethyl-5-(1-methylbutyl)-2-thio-, sodium salt (8CI)
• Intra-Vital Sodium
• hypnostan
• intravalsodium
• leopental
• monosodium5-ethyl-5-(1-methylbutyl)thiobarbiturate
• nesdonalsodium
• penthiobarbitalsodium
• pentothalsodium
• ravonal
• sodium5-ethyl-5-(1-methylbutyl)-2-thiobarbiturate
• sodiumpenthiobarbital
• sodiumpentothal
• sodiumpentothiobarbital