(S)-5-Hydroxymethyldihydrofuran-2-one
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- CAS-Nr.
- 32780-06-6
- Englisch Name:
- (S)-5-Hydroxymethyldihydrofuran-2-one
- Synonyma:
- 5-(Hydroxymethyl)dihydro-2(3H)-furanone;(S)-(+)-γ-Hydroxymethyl-γ(S)-Gamma-Hydroxymethyl-Gamma;(S)-4-HYDROXYMETHYL BUTYROLACTONE;(5S)-5-(hydroxyMethyl)oxolan-2-one;(s)-γ-hydroxymethyl-γ-butyrolactone;(S)-5-Hydroxymethyldihydrofuran-2-on;(S)-(+)-G-HYDROXYMETHYL-G-BUTYROLACTONE;(S)-5-HYDROXYMETHYL-DIHYDRO-FURAN-2-ONE
- CBNumber:
- CB6702069
- Summenformel:
- C5H8O3
- Molgewicht:
- 116.12
- MOL-Datei:
- 32780-06-6.mol
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(S)-5-Hydroxymethyldihydrofuran-2-one Eigenschaften
- Schmelzpunkt:
- 72-74 °C
- Siedepunkt:
- 110-115 °C/0.2 mmHg (lit.)
- alpha
- 56 º (c=3 in chloroform)
- Dichte
- 1.237 g/mL at 25 °C (lit.)
- Brechungsindex
- n20/D 1.471(lit.)
- Flammpunkt:
- >230 °F
- storage temp.
- 2-8°C
- pka
- 14.12±0.10(Predicted)
- Aggregatzustand
- clear liquid
- Farbe
- Colorless to Almost colorless
- Optische Aktivit?t
- [α]20/D +56°, c = 3 in chloroform
- BRN
- 1680284
- CAS Datenbank
- 32780-06-6(CAS DataBase Reference)
- NIST chemische Informationen
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Bildanzeige (GHS) |
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Alarmwort |
Warnung |
Gefahrenhinweise |
Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
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Sicherheit |
P264 |
Nach Gebrauch gründlich waschen. |
P264 |
Nach Gebrauch gründlich waschen. |
P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
P332+P313 |
Bei Hautreizung: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
P337+P313 |
Bei anhaltender Augenreizung: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
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(S)-5-Hydroxymethyldihydrofuran-2-one Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
Colorless to light yellow liqui
Verwenden
(
S)-(+)-Dihydro-5-(hydroxymethyl)-2(3
H)-furanone can be used as a chiral synthon to synthesize:
- Potent nucleoside, acetylcholine, and (+)-muricatacin analogs.
- Mevinic acids, which are LDL cholesterol-lowering agents.
- Adenine based anti-HIV agent named β-F-ddA.
Allgemeine Beschreibung
Dihydro-5-(hydroxymethyl)-2(3
H)-furanone is a chiral building block widely used in the synthesis of many natural products and few biologically significant compounds like anti-HIV dideoxynucleosides. It is also used in the synthesis of optically active ligands.
(S)-5-Hydroxymethyldihydrofuran-2-one Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Dimethylsulfid-Boran
Glutaminsure
Natriumnitrit
Tetrahydrofuran
Benzol
Ethylacetat
Hydrogenchlorid
Methanol
Ligroin
Pentanoic acid, 4,5-dihydroxy-, methyl ester, (4S)-
D-threo-Pentonic acid, 2-deoxy-, γ-lactone
(5S)-5-(trityloxymethyl)-5H-furan-2-one
2-Oxiranepropanoic acid, methyl ester, (2R)-
2-Oxiranepropanoic acid, methyl ester
(S)-(+)-GAMMA-(TRITYLOXYMETHYL)-GAMMA-BUTYROLACTONE
(S)-(-)HYDROXYMETHYL-3(2H)-FURANONE
(1S,5R)-6,8-dioxabicyclo[3.2.1]octan-4-one
Downstream Produkte
(S)-5-Hydroxymethyldihydrofuran-2-one Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 166)Lieferanten
32780-06-6()Verwandte Suche:
- (S)-(+)-gamma-Hydroxymethyl-gamma-butyrolactone,97%
- (S)-Gamma-Hydroxymethyl-Gamma
- (S)-(+)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone ,97%
- (5S)-5-(HYDROXYMETHYL)-3,4,5-TRIHYDROFURAN-2-ONE
- (5S)-(+)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one
- (S)-(+)-4,5-Dihydro-5-hydroxymethyl-2(3H)-furanone
(S)-(+)-5-Hydroxymethyltetrahydro-2-furanone
- 5-Oxo-tetrahydro-furan-2-carboxylic acid ethyl ester
- (5S)-5-(hydroxyMethyl)oxolan-2-one
- 2(3H)-Furanone,dihydro-5-(hydroxyMethyl)-, (5S)-
- (S)-(+)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone 95%
- (S)-(+)-&gamma
- -Hydroxymethyl-&gamma
- (S)-(+)-DIHYDRO-5-(HYDROXYMETHYL)-2(3H)-FURANONE
- (S)-(+)-DIHYDRO-5-(HYDROXYMETHYL)FURANONE
- (S)-(+)-GAMMA-HYDROXYMETHYL-GAMMA-BUTYROLACTON
- (S)-(+)-GAMMA-HYDROXYMETHYL-GAMMA-BUTYROLACTONE
- (S)-GAMMA-HYDROXYMETHYL-GAMMA-BUTYROLACTONE
- (S)-(+)-G-HYDROXYMETHYL-G-BUTYROLACTONE
- (S)-(+)-4,5-DIHYDRO-5-HYDROXYMETHYL-2(3H)-FURANONE
- (S)-4,5-DIHYDRO-5-HYDROXYMETHYL-2(3H)-FURANONE
- DIHYDRO-5-(HYDROXYMETHYL)-2(3H)-FURANONE (S-)
- 2(3H)-FURANONE, DIHYDRO-5-(HYDROXYMETHYL)-,(S)
- (S)-4-HYDROXYMETHYL BUTYROLACTONE
- (S)-5-HYDROXYMETHYL-2-OXOTETRAHYDROFURAN
- (S)-5-HYDROXYMETHYL-DIHYDRO-FURAN-2-ONE
- (S)-(+)-5-HYDROXYMETHYL-GAMMA-BUTYROLACTONE
- (S)-(+)-5-HYDROXYMETHYLTETRAHYDRO-2-FURANONE
- (S)-γ-Hydroxymethyl-γ-butyrolactone, (S)-4,5-Dihydro-5-hydroxymethyl-2(3H)-furanone, (S)-5-Hydroxymethyl-2-oxotetrahydrofuran
- (S)-4,5-Dihydro-5-hydroxymethyl-2(3H)-furanone, (S)-5-Hydroxymethyl-2-oxotetrahydrofuran
- (S)-(+)-DIHYDRO-5-(HYDROXYMETHYL)-2(3H)- FURANONE, 95% (98% EE/GLC)
- (S)-GAMMA-HYDROXYMETHYL-GAMMA-BUTYRO- &
- (s)-γ-hydroxymethyl-γ-butyrolactone
- (S)-(+)-5-HYDROXYMETHYL-GAMMA-BUTYROLACTONE 98%
- (5S)-5-(hydroxymethyl)-2-oxo-tetrahydrofuran
- (S)-5-Hydroxymethyldihydrofuran-2-on
- (S)-(+)-γ-Hydroxymethyl-γ-butyrolactone>
- 5-(Hydroxymethyl)dihydro-2(3H)-furanone
- (5S)-5-(Hydroxymethyl)dihydro-2(3H)-furanone
- 32780-06-6
- Asymmetric Synthesis
- Chiral Building Blocks
- Heterocyclic Building Blocks
- Furans
- chiral
- Chiral Reagent