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4-Amino-7H-pyrrolo[2,3-d]pyrimidine

4-Amino-7H-pyrrolo[2,3-d]pyrimidine Struktur
1500-85-2
CAS-Nr.
1500-85-2
Englisch Name:
4-Amino-7H-pyrrolo[2,3-d]pyrimidine
Synonyma:
7-DEAZAADENINE;6-Amino-7-deazapurine;6-AMino-7-deazapurine 97%;4-Amino-7H-pyrrolo[2,3-d]...;4-Aminopyrrolo[2,3-d]Pyrimidin;4-AMINOPYRROLO[2,3-D]PYRIMIDINE;1H-Pyrrolo[2,3-d]pyrimidin-4-amin;7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE;3-d)pyrimidine,4-amino-7h-pyrrolo(;4-Amino-7H-pyrrolo[2,3-d]pyrimidine
CBNumber:
CB6306218
Summenformel:
C6H6N4
Molgewicht:
134.14
MOL-Datei:
1500-85-2.mol

4-Amino-7H-pyrrolo[2,3-d]pyrimidine Eigenschaften

Schmelzpunkt:
257-262℃
Siedepunkt:
318.3±45.0 °C(Predicted)
Dichte
1.61±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
13.38±0.20(Predicted)
Aggregatzustand
Solid
Farbe
White to pale brown
Sensitive 
Moisture & Light Sensitive
InChIKey
PEHVGBZKEYRQSX-UHFFFAOYSA-N
CAS Datenbank
1500-85-2(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher T
R-S?tze: 25
S-S?tze: 45
RIDADR  UN 2811 6.1/PG 1
WGK Germany  2
RTECS-Nr. UY8850000
HazardClass  IRRITANT
PackingGroup 
HS Code  2933599590
Toxizit?t mouse,LD50,intraperitoneal,300mg/kg (300mg/kg),Gann. Japanese Journal of Cancer Research. Vol. 56, Pg. 219, 1965.
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H301 Giftig bei Verschlucken. Akute Toxizit?t oral Kategorie 3 Achtung GHS hazard pictogramssrc="/GHS06.jpg" width="20" height="20" /> P264, P270, P301+P310, P321, P330,P405, P501
Sicherheit
P301+P310 BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.

4-Amino-7H-pyrrolo[2,3-d]pyrimidine Chemische Eigenschaften,Einsatz,Produktion Methoden

Synthese

A mixture of 5-ethynylpyrimidine-4,6-diamine (300?mg, 2.24?mmol), Cs2CO3 (1.46?g, 4.47?mmol) and DMSO (4.00?ml) in a 10.00?ml microwave tube was irradiated at 100?W and 180?°C for 15?minutes. After this time, the reaction mixture was cooled to room temperature and poured into a separating funnel containing 100?ml water and 100?ml ethyl acetate. The aqueous layer was extracted with EtOAc (2×100?ml). The combined organic extracts were dried with MgSO4 and filtered through celite, and excess solvent was removed in vacuo. Purification by column chromatography (80?% EtOAc/hexane – 10?% MeOH/CH2Cl2) gave 7H-pyrrolo[2,3-d]pyrimidin-4-amine (4-Amino-7H-pyrrolo[2,3-d]pyrimidine) (0.15?g, 50?%) as an off-white solid[1].

4-Amino-7H-pyrrolo[2,3-d]pyrimidine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


4-Amino-7H-pyrrolo[2,3-d]pyrimidine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 221)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Capot Chemical Co.,Ltd.
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0519-86626038
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FandaChem@Gmail.com China 9080 55
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Alchem Pharmtech,Inc.
8485655694
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Wuhan Chemwish Technology Co., Ltd
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1500-85-2()Verwandte Suche:


  • 6-AMino-7-deazapurine 97%
  • 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 6-Amino-7-deazapurine
  • 7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE
  • 7-DEAZAADENINE
  • 4-AMINOPYRROLO[2,3-D]PYRIMIDINE
  • 4-Amino-7H-pyrrolo[2,3-d]pyrimidine
  • 3-d)pyrimidine,4-amino-7h-pyrrolo(
  • 6-Amino-7-deazapurine
  • 1H-Pyrrolo[2,3-d]pyrimidin-4-amine (9CI)
  • 4-Aminopyrrolo[2,3-d]Pyrimidin
  • 4-AMINO-7H-PYRROLO[2,3-D]PYRIMIDINE SULFATE 98%
  • 7H-Pyrrolo[2,3-D]pyrimidin-4-ylamine
  • 4-Amino-7H-pyrrolo[2,3-d]...
  • 4-Amino-7H-pyrrolo[2,3-d]pyrimidine ISO 9001:2015 REACH
  • 1H-Pyrrolo[2,3-d]pyrimidin-4-amin
  • 1500-85-2
  • 856600-01-2
  • Heterocycle-Pyrimidine series
  • Building Blocks
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Purines
  • Heterocycles series
  • Amines
  • Fused Ring Systems
  • PYRIMIDINE
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