3-Aminopropan-1,2-diol
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3-Aminopropan-1,2-diol Eigenschaften
- Schmelzpunkt:
- 55-57 °C
- Siedepunkt:
- 264-265 °C739 mm Hg(lit.)
- Dichte
- 1.175 g/mL at 25 °C(lit.)
- Dampfdruck
- <1 hPa (20 °C)
- Brechungsindex
- n
20/D 1.492(lit.)
- Flammpunkt:
- >230 °F
- storage temp.
- Store below +30°C.
- L?slichkeit
- >1000g/l soluble
- pka
- 12.11±0.35(Predicted)
- Aggregatzustand
- liquid (highly viscous)
- Farbe
- Clear colorless to pale yellow
- Wichte
- 1.175
- PH
- 11 (100g/l, H2O, 20℃)
- Wasserl?slichkeit
- soluble
- Sensitive
- Hygroscopic
- BRN
- 1719121
- InChIKey
- KQIGMPWTAHJUMN-UHFFFAOYSA-N
- LogP
- -2.079 (est)
- CAS Datenbank
- 616-30-8(CAS DataBase Reference)
- NIST chemische Informationen
- 3-Amino-1,2-propanediol(616-30-8)
- EPA chemische Informationen
- 1,2-Propanediol, 3-amino- (616-30-8)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher | C,Xi | ||
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R-S?tze: | 34-36/37/38 | ||
S-S?tze: | 26-36/37/39-45-36 | ||
RIDADR | UN 2735 8/PG 2 | ||
WGK Germany | 2 | ||
RTECS-Nr. | TY2800000 | ||
F | 10-21 | ||
Hazard Note | Corrosive | ||
TSCA | Yes | ||
HazardClass | 8 | ||
PackingGroup | III | ||
HS Code | 29221980 | ||
Toxizit?t | LD50 orally in Rabbit: 7500 mg/kg |
Bildanzeige (GHS) | |||||||||||||||
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Alarmwort | Achtung | ||||||||||||||
Gefahrenhinweise |
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Sicherheit |
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3-Aminopropan-1,2-diol Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R34:Verursacht Ver?tzungen.R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
3-Amino-1,2-propanediol (APD) is a calcium metabolism regulator useful in the treatment of Paget's disease, tumor-induced hypercalcemia and other bone disorders involving increased osteoclastic activity.Chemische Eigenschaften
3-Amino-1,2-propanediol is a very viscous transparent colorless to pale yellow liquid with a melting point of 55-57 °C and a boiling point of 264-265 °C. The density at 25 °C is 1.175 g/mL. soluble in water.Verwenden
3-Amino-1,2-propanediol is used in the preparation of iohexol, which is a X-CT non-ionic contrast medium. It acts as a starting material in the production of specialty materials.Application
3-Amino-1,2-propanediol is used as a reactant in the synthesis of lipid-like delivery molecules(lipidoids) for RNA interference (RNAi) therapeutics. It is also used in the synthesis of the bioactive template to prepare cationic α-helical polypeptides and various cationic polymers for gene delivery. It is also used in the synthesis of Decarbazolyl Carvedilol (D212720), a metabolite of Carvedilol (C184625) found in humans, rats, dogs and mice.synthetische
3-Amino-1,2-propanediol is synthesized by reacting 3-chloro-1,2-propanediol (CPD) with ammonia in alkaline environment by adding sodium hydroxide. Afterwards, the product undergoes a series of purification steps.Allgemeine Beschreibung
3-Amino-1,2-propanediol is a chiral glycerol derivative. It could used as a hydrogen bond donor in the design of a new deep eutectic solvent which have emerged as a suitable alternative to VOCs (volatile organic compounds) for diverse practical applications including, among others, drug delivery, electrochemistry, material design, extractions and, of course, organic reactions, alone or together twith other sustainable reaction-media[1]. It can also used as a core present in antiviral compounds to skeleton to design a novel class of anti-adenovirus agents[2].Hazard
3-Amino-1,2-propanediol is Danger.H314 (93.33%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
H318 (56.36%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
Sicherheitsprofil
Poison by intraperitoneal route.Moderately toxic by ingestion. When heated todecomposition it emits toxic fumes of NOx.Lager
3-Amino-1,2-propanediol absorbs moisture and needs to be kept in a container sealed. Store in cool, dry conditions in well-sealed containers.3-Aminopropan-1,2-diol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3-Aminopropan-1,2-diol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 513)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
Hebei Weibang Biotechnology Co., Ltd | +8615531157085 |
abby@weibangbio.com | China | 8810 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12835 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5857 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 |
sales1@chuanghaibio.com | China | 5889 | 58 |
Hebei Weibang Biotechnology Co., Ltd | +8617732866630 |
bess@weibangbio.com | China | 18151 | 58 |
Firsky International Trade (Wuhan) Co., Ltd | +8615387054039 |
admin@firsky-cn.com | China | 427 | 58 |
Sichuan HongRi Pharma-Tech Co.,Ltd | +86-028-64841719 +8617390183901 |
daisy@enlaibio.com | China | 1106 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 20284 | 58 |
Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 |
admin@zlchemi.com | China | 3002 | 58 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 18751 | 58 |
616-30-8(3-Aminopropan-1,2-diol)Verwandte Suche:
(R)-(-)-1,2-Propanediol
2-Methoxy-1-methylethylacetat
Propan-1,2-diol
Propan-1,3-diol
Glycin
ALTRENOGEST
3-Aminophenol
1-Phenoxypropan-2-ol
(2-Butoxymethylethoxy)propanol
1-Methoxypropan-2-ol
Aminocapronsure
2-METHYL-1,3-PROPANEDIOL
3-Aminopropan-1-sulfonsaeure
Trometamol
2-Aminopropan-1,3-diol
[S(R*,R*)]-2-Amino-1-phenylpropan-1,3-diol
PROPANEDIOL
3-(N-Ethyl-m-toluidino)propan-1,2-diol
- 3-AMino-1,2-propanediol, 98% 25GR
- 3-AMINO-1,2-PROPANEDIOL FOR SYNTHESIS
- 3 - aMino - 1, 2 - propylene glycol
- 3-AMINO-1,2-DIHYDROXYPROPANE
- (+/-)-3-AMINO-1,2-PROPANEDIOL
- 3-AMINO-1,2-PROPANEDIOL
- 2,3-DIHYDROXY-1-PROPYLAMINE
- 1-AMINO-2,3-PROPANDIOL
- 1-AMINO-2,3-PROPANEDIOL
- 1-AMINOGLYCEROL
- 1,2-DIHYDROXY-3-AMINOPROPANE
- 1,2-DIHYDROXY-1-PROPYLAMINE
- 1,2-Propanediol, 3-amino-
- 1-aminopropanediol
- 2,3-Dihydroxypropylamine
- 2,3-Propandiol-1-amine
- 3-amino-2-propanediol
- (+/-)-3-AMINO-1,2-PROPANEEDIOL
- 3-AMINO-1,2-PROOPANEDIOL
- 3-Aminopropane-1,2-diol 99%
- 3-AMINO-1,2-PROPANEDIOL 98%
- Aminopropylene glycol
- 1-Amino-2,3-dihydroxypropane
- Glycerol α-monoamine
- 3-Amino-1,2-propanediol,98%
- 3-Amino-1,2-propanediol (Isoserinol)
- 3-Amino-1,2-propaned
- 3-AMNIO-1,2-PROPANEDIOL
- 3-AMino-1,2-propanediol, 98% 100GR
- 3-Amino-1,2-propanediol USP/EP/BP
- 3-AMINO-1,2-PROPANDIOL
- Isoserinol
- 3-AMINOPROPANE-1,2-DIOL
- AMINOPROPANEDIOL
- APD
- (+/-)-3-AMINO-1,2-PROPANEDIOL
- 3-amino-1,2-propanediol (APD)
- 1-Aminopropan-2,3-diol
- 3--1,2-
- Ethyl Acetate Impurity 32
- 616-30-8
- NH2CH2CHOHCH2OH
- AMINE
- Oxygen Compounds
- Organic Building Blocks
- Amino Alcohols
- Building Blocks
- API
- Alcohols and Derivatives
- Amino Alcohols
- Organic Building Blocks
- Oxygen Compounds
- 616-30-8