天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Progesteron

Progesterone Struktur
57-83-0
CAS-Nr.
57-83-0
Bezeichnung:
Progesteron
Englisch Name:
Progesterone
Synonyma:
Lutein;PROCYANIDINS;Progesteron;Progestrone;Lutin;progestin;Luteine;Prometrium;Pregn-4-ene-3,20-dione;CIDR
CBNumber:
CB4224484
Summenformel:
C21H30O2
Molgewicht:
314.46
MOL-Datei:
57-83-0.mol

Progesteron Eigenschaften

Schmelzpunkt:
128-132 °C (lit.)
Siedepunkt:
394.13°C (rough estimate)
alpha 
186 º (c=1, ethanol)
Dichte
d23 1.166; d20 1.171
Brechungsindex
182 ° (C=2, Dioxane)
Flammpunkt:
2℃
storage temp. 
room temp
L?slichkeit
H2O: 25 mg/mL, may be clear to slightly hazy
Aggregatzustand
powder
Farbe
Yellow to yellow-brown
Wasserl?slichkeit
<0.1 g/100 mL at 19 ºC
Merck 
7773
BRN 
1915950
BCS Class
4
Stabilit?t:
Stable. Incompatible with strong oxidizing agents.
InChIKey
RJKFOVLPORLFTN-LEKSSAKUSA-N
LogP
3.870
CAS Datenbank
57-83-0(CAS DataBase Reference)
NIST chemische Informationen
Progesterone(57-83-0)
EPA chemische Informationen
Progesterone (57-83-0)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn,T,F
R-S?tze: 40-45-62-36-20/21/22-11
S-S?tze: 36/37-45-53-16
RIDADR  UN 1648 3 / PGII
WGK Germany  3
RTECS-Nr. TW0175000
HS Code  29372390
Giftige Stoffe Daten 57-83-0(Hazardous Substances Data)
Toxizit?t LD50 intraperitoneal in rat: 327mg/kg
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H351 Kann vermutlich Krebs verursachen. Karzinogenit?t Kategorie 2 Warnung P201, P202, P281, P308+P313, P405,P501
H362 Kann S?uglinge über die Muttermilch sch?digen. Reproductive toxicity, effects on or via lactation Additional category P201, P260, P263, P264, P270,P308+P313
Sicherheit
P202 Vor Gebrauch alle Sicherheitshinweise lesen und verstehen.
P260 Dampf/Aerosol/Nebel nicht einatmen.
P263 Kontakt w?hrend der Schwangerschaft /und der Stillzeit vermeiden.
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P308+P313 BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.

Progesteron Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R40:Verdacht auf krebserzeugende Wirkung.
R45:Kann Krebs erzeugen.

S-S?tze Betriebsanweisung:

S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.

Beschreibung

Progesterone, along with pregnenolone, is the biosynthetic precursor of all other steroid hormones. Progesterone is synthesized from cholesterol by the sequential action of desmolase in the mitochondria, which produces pregnenolone, followed by Δ4,5-isomerase in the outer mitochondrial membrane and smooth endoplasmic reticulum of steroid-secreting cells. Progesterone activates the human progesterone receptor with an EC50 value of 0.5 nM.

Chemische Eigenschaften

White powder. Melting point 121°C. Stable in air. Insoluble in water. A female sex hormone. Low toxicity.

Occurrence

Colchicum luteum also yields this alkaloid.

Definition

ChEBI: Progesterone is a C21-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species. It has a role as a contraceptive drug, a progestin, a progesterone receptor agonist, a human metabolite and a mouse metabolite. It is a 20-oxo steroid, a 3-oxo-Delta(4) steroid and a C21-steroid hormone. It derives from a hydride of a pregnane.

Allgemeine Beschreibung

Progesterone, pregn-4-en-3,20-dione, is so rapidly metabolized that it is not particularlyeffective orally, being only one twelfth as active as intramuscularly.An oral formulation of micronized progesterone(Prometrium) is available. Progesterone given intramuscularlycan be very irritating. A vaginal gel containing 4% or8% progesterone offers an alternative dosage form.Progesterone was originally obtained from animal ovariesbut is now prepared synthetically from plant sterol precursors.The discovery of 19-nortestosterones with progesteroneactivity made synthetically modified progestins of tremendoustherapeutic importance.
Progesterone (and all other steroid 4-ene-3-ones) is lightsensitive and should be protected from light.

Air & Water Reaktionen

Insoluble in water.

Reaktivit?t anzeigen

Progesterone is sensitive to light .

Hazard

A carcinogen (OSHA).

Health Hazard

ACUTE/CHRONIC HAZARDS: Progesterone may be absorbed through the skin.

Brandgefahr

Flash point data for Progesterone are not available; however, Progesterone is probably combustible.

Biologische Aktivit?t

Endogenous progesterone receptor (PR) agonist (EC 50 = 0.5 nM).

Nebenwirkungen

Common side effects of oral Progesterone include: chest pain, chills, cold or flu-like symptoms; cough or hoarseness; fever, and problems with urination. Rare side effects include: clear or bloody discharge; dimpling of the breast skin, lumps in the breast or armpit; persistent crusting or flaking; redness or swelling of the breast; and sores on the breast skin that do not heal. Other side effects that may occur are: abdominal or stomach pain; constipation, difficulty breathing, dizziness, fast, strong, or irregular heartbeat or pulse; headache, measles, indigestion, itching, joint pain, stiffness, or swelling; rash.

Sicherheitsprofil

NTP 10th Report on Carcinogens. IARC Cancer Review: Animal Lirmted Evidence IMEMDT 21,491,79; Animal Sufficient Evidence IMEMDT 6,135,74. EPA Genetic Toxicology Program. Reported in EPA TSCA Inventory. SAFETY PROFILE: Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Poison by intravenous and intraperitoneal routes. Human teratogenic effects by ingestion and parenteral routes: developmental abnormalities of the urogenital system. Human male reproductive effects by intramuscular route: changes in spermatogenesis, the prostate, seminal vesicle, Cowper's gland and accessory glands, impotence, and breast development. Human female reproductive effects by ingestion, parenteral, and intravaginal routes: ferthty changes; menstrual cycle changes and disorders; uterus, cervix, and vagina changes. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.

Carcinogenicity

Progesterone is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

l?uterung methode

The form crystallises from EtOH with m 127-131o. The -form crystallises from pet ether or aqueous pet ether/aqueous Et2O with m 119-120o or 121o. It also crystallises from Et2O, Me2CO/EtOAc, MeOH, aqueous Et2O, aqueous MeOH, wet pet ether, Et2O/pet ether, pet ether/*C6H6, Et2O/pentane and isopropyl ether. The is at 240nm with log 4.25 (EtOH). [Wintersteiner & Allen J Biol Chem 107 max 321 1934, Beilstein 7 III 3648, 7 IV 2395.]

Progesteron Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Progesteron Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 922)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Wuhan Haorong Biotechnology Co.,ltd
+86-18565342920; +8618565342920
sales@chembj.net China 289 58
Baoji Guokang Bio-Technology Co., Ltd.
0917-3909592 13892490616
gksales1@gk-bio.com China 9312 58
APOLLO HEALTHCARE RESOURCES
+6596580999
sales@apollo-healthcare.com.sg Singapore 399 58
Pharmaceuticals Group Corp., Ltd.
+8613004379774
wu@jiaerke.com China 33 58
airuikechemical co., ltd.
+undefined86-15315557071
sales02@sdzhonghuimaterial.com China 983 58
Shanghai Likang New Materials Co., Limited
+86-16631818819 +86-17736933208
3684455296@qq.com China 9300 58
Hangzhou Hyper Chemicals Limited
+86-0086-57187702781 +8613675893055
info@hyper-chem.com China 295 58
Wuhan Fortuna Chemical Co., Ltd
+86-027-59207850
info@fortunachem.com China 5975 58
Dorne Chemical Technology co. LTD
+86-86-13583358881 +8618560316533
Ethan@dornechem.com China 3097 58
Sinoway Industrial co., ltd.
0592-5800732; +8613806035118
xie@china-sinoway.com China 988 58

57-83-0(Progesteron)Verwandte Suche:


  • Cyclogest
  • delta(Sup4)-pregnene-3,20-dione
  • delta-Pregnene-3,20-dione
  • Gesterol
  • Gesterol 100
  • Gesterol 50
  • gesterol100
  • Gestiron
  • Gestormone
  • Gestron
  • Luteum
  • Lutex
  • Lutidon
  • Lutociclina
  • Lutocuclin M
  • Lutocyclin m
  • lutocyclinm
  • Lutocylin
  • Lutoform
  • Lutogyl
  • Lutromone
  • Membrettes
  • Methylpregnone
  • Nalutron
  • NSC-9704
  • Percutacrine
  • Percutacrine luteinique
  • percutacrineluteinique
  • Piaponon
  • Pregn-4-en-3,20-dione
  • Pregn-4-ene-3,20-dione, 17alpha-hydroxy-6alpha-methyl-
  • Pregnene-3,20-dione
  • Pregnenedione
  • Progekan
  • pregesterone
  • Progesterone Injection
  • PROGESTERONE USP MICRONIZED
  • PROGESTERONE USP
  • PROGESTERONE, CELL CULTURE TESTED
  • Progesterone, Topical, Powder, Micronized
  • grogesterone
  • HYDROXY PROGESTERRONE CAPTORATE BP98
  • Progeseterone
  • (8S,9S,10R,13S,14S,17S)-17-Acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
  • Progesterone,98%
  • PROGESTERONEANALYTICAL GRADE
  • Progesterone,4-Pregnene-3,20-dione
  • Progesterone (200 mg)
  • Progesterone (200 mg)I0D3730.998mg/mg(ai)
  • Progesterone COS
  • (8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-diMethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one
  • PROGESTERONE(AS)
  • Progesterone for system suitability
  • Progesterone for peak identification
  • Lutein and zeaxanthin in corn oil
  • Progesterone: 2-hydroxypropyl-β-cyclodextrin complex
  • Progesterone: HBC complex
  • Progesterone solution
Copyright 2019 ? ChemicalBook. All rights reserved