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4-Hydroxybenzylalkohol

4-Hydroxybenzyl alcohol Struktur
623-05-2
CAS-Nr.
623-05-2
Bezeichnung:
4-Hydroxybenzylalkohol
Englisch Name:
4-Hydroxybenzyl alcohol
Synonyma:
4-(Hydroxymethyl)phenol;P-HYDROXYBENZYL ALCOHOL;Gastrodigenin;p-Hydroxybenzyl;p-Methylolphenol;4-hydroxyphenyl Methanol;P-hydroxylbenzyl alcohol;Benzenemethanol, 4-hydroxy-;FEMA 3987;ω-Hydroxycresol
CBNumber:
CB3224331
Summenformel:
C7H8O2
Molgewicht:
124.14
MOL-Datei:
623-05-2.mol

4-Hydroxybenzylalkohol Eigenschaften

Schmelzpunkt:
114-122 °C(lit.)
Siedepunkt:
251-253°C
Dichte
1.1006 (rough estimate)
Brechungsindex
1.5035 (estimate)
FEMA 
3987 | 4-HYDROXYBENZYL ALCOHOL
Flammpunkt:
251-253°C
storage temp. 
Store below +30°C.
L?slichkeit
6.7g/l soluble
pka
pK1:9.82 (25°C)
Aggregatzustand
Crystalline Powder
Farbe
Pink to beige
Geruch (Odor)
at 100.00 %. fruity bitter almond sweet coconut
Geruchsart
fruity
Wasserl?slichkeit
Soluble in water (6.7 mg/ml at 20°C), dioxane (100 mg/ml), 1N NaOH (50 mg/ml), DMSO, and methanol.
Sensitive 
Light Sensitive/Air Sensitive
JECFA Number
955
BRN 
1858967
InChIKey
BVJSUAQZOZWCKN-UHFFFAOYSA-N
LogP
0.21
CAS Datenbank
623-05-2(CAS DataBase Reference)
NIST chemische Informationen
Benzenemethanol, 4-hydroxy-(623-05-2)
EPA chemische Informationen
4-Hydroxybenzenemethanol (623-05-2)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi
R-S?tze: 36-36/37/38
S-S?tze: 26-24/25-36
WGK Germany  3
RTECS-Nr. DA4796800
8-9-23
Hazard Note  Irritant/Keep Cold/Air Sensitive/Light Sensitive
HS Code  29072900
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H412 Sch?dlich für Wasserorganismen, mit langfristiger Wirkung. Langfristig (chronisch) gew?ssergef?hrdend Kategorie 3 P273, P501
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P273 Freisetzung in die Umwelt vermeiden.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.
P337+P313 Bei anhaltender Augenreizung: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

4-Hydroxybenzylalkohol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36:Reizt die Augen.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Chemische Eigenschaften

4-Hydroxybenzyl alcohol is a white crystalline powder with slightly fruity-sweet coconut odor

Occurrence

Reportedly found in vanilla, Bourbon (Vanilla plantifolia Andrew

Verwenden

4-Hydroxybenzyl alcohol is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

Definition

ChEBI: P-hydroxybenzyl alcohol is a member of the class of benzyl alcohols that is benzyl alcohol substituted by a hydroxy group at position 4. It has been isolated from Arcangelisia gusanlung. It has a role as a plant metabolite. It is a member of phenols and a member of benzyl alcohols.

synthetische

Prepared from p-cresol by using the microorganism, Pseudomonas putida.

Allgemeine Beschreibung

4-Hydroxybenzyl alcohol (HBA) is a phenolic compound found in Gastrodia elata. It is as an antioxidant and anti-asthmatic agent.

Kontakt-Allergie

Methylol phenols are sensitizers contained in resins based on phenol and formaldehyde of the resol type. Cross-reactivity is possible with other phenol derivative molecules.

IC 50

IC50 >0.2 mM (human); ALDH5A1: IC50 >1 mM (human); ABAT: IC50 >1 mM (human); Tyrosinase: IC50 >1 mM (Agaricus bisporus)

l?uterung methode

Crystallise the alcohol from H2O, *C6H6 (m 124o), *C6H6/EtOH or ClCH2CH2Cl (m 122o). [Beilstein 6 III 4546, 6 IV 5909.]

4-Hydroxybenzylalkohol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


4-Hydroxybenzylalkohol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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623-05-2(4-Hydroxybenzylalkohol)Verwandte Suche:


  • 4-(Hydroxymethyl)phenol 98%
  • 4-Hydroxybenzyl alcohol, (4-Hydroxyphenyl)methanol
  • 4-Hydroxybenzyl alcohol, 97% 25GR
  • The hydroxy benzyl alcohol
  • P-(HYDROXYMETHYL)PHENOL
  • RARECHEM AL BD 0098
  • 4-METHYLOLPHENOL
  • 4-HYDROXYBENZYL ALCOHOL
  • 4-hydroxybenzenemethanol
  • HYDROXYBENZYL-4 ALCOHOL
  • FEMA 3987
  • alpha-Hydroxy-p-cresol
  • Benzyl alcohol, p-hydroxy-
  • p-Hydroxy Benzyl Alcohol 4-Hydroxy Benzyl Alcohol
  • 4-HYDROXYBENZYL ALCOHOL 98+%
  • 4-HydroxybenzylAlcohol99%
  • PARA-HYDROXYBENZOYLALCOHOL
  • PARA-ALCOHOLPHENOL
  • 4-HYDROXYBENZYL ALCOHOL 99%
  • p-Hydroxybenzenemethanol
  • ω-Hydroxycresol
  • 4-Hydroxybenzyl alcohol,97%
  • 4-Hydroxbenzyl alcohol
  • (4-hydroxybenzyl)ether
  • 4-Hydroxybenzylic Alcohol
  • Bisoprolol Impurity 19
  • α,4‐Dihydroxytoluene
  • 4 Hydroxy benzyl alcohol (CAS No: 623-05-2)
  • Bisoprolol Alcohol Impurity (Gastrodigenin)
  • 4-Hydroxybenzyl Alcohol >
  • 4-HYDROXYBENZYL ALCOHOL FOR SYNTHESIS
  • Bisoprolol Impurity 13 (Gastrodigenin)
  • Para Hydroxylbenzyl alcohol
  • Bisoprolol Impurity 33
  • 4-(Hydroxymethyl)phenol (BPL-I)
  • 4-Hydroxy Benzyl Alcohol pure, 98%
  • Bisoprolol Alcohol ImpurityQ: What is Bisoprolol Alcohol Impurity Q: What is the CAS Number of Bisoprolol Alcohol Impurity Q: What is the storage condition of Bisoprolol Alcohol Impurity Q: What are the applications of Bisoprolol Alcohol Impurity
  • 4-hydroxyphenyl Methanol
  • P-HYDROXYBENZYL ALCOHOL
  • P-hydroxylbenzyl alcohol
  • 4-(Hydroxymethyl)phenol
  • Gastrodigenin
  • p-Methylolphenol
  • p-Hydroxybenzyl
  • Benzenemethanol, 4-hydroxy-
  • 4-HYDROXY BENZYLALCHOHOL
  • PARA HYDROXY BENZYL ALCOHOL
  • 4-Hydroxybenzyl alcohol, p-Hydroxybenzyl alcohol, 4-(Hydroxymethyl)phenol, Gastrodigenin, p-Hydroxybenzyl, p-Methylolphenol, 4-hydroxyphenyl Methanol, p-hydroxylbenzyl alcohol, Benzenemethanol, 4-hydroxy-, FEMA 3987, ω-Hydroxycresol
  • 623-05-2
  • 0623-05-02
  • Alcohols
  • Building Blocks
  • C7 to C8
  • Organic Building Blocks
  • Oxygen Compounds
  • Aromatics
  • Benzhydrols, Benzyl & Special Alcohols
  • Alphabetical Listings
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