天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Prostaglandin F2a

Prostaglandin F2a Struktur
551-11-1
CAS-Nr.
551-11-1
Englisch Name:
Prostaglandin F2a
Synonyma:
glandin;u-14583;cyclosin;Dinprost;enzaprost;dinolytic;panacelan;Glandin N;DINOPROST;Dinaprost
CBNumber:
CB3161368
Summenformel:
C20H34O5
Molgewicht:
354.49
MOL-Datei:
551-11-1.mol

Prostaglandin F2a Eigenschaften

Schmelzpunkt:
25-35°
alpha 
D25 +23.5° (c = 1 in tetrahydrofuran)
Siedepunkt:
407.69°C (rough estimate)
Dichte
1.0458 (rough estimate)
Brechungsindex
1.6120 (estimate)
storage temp. 
Store at -20°C
L?slichkeit
DMSO:100.0(Max Conc. mg/mL);282.1(Max Conc. mM)
Water:100.0(Max Conc. mg/mL);282.1(Max Conc. mM)
pka
pKa 4.90(H2O,t=25±2,I=0.0,c<0.01,N2) (Uncertain)
Aggregatzustand
Low melting white solid or colorless oil.
Farbe
White to light brown
InChIKey
PXGPLTODNUVGFL-JPYXJAOSNA-N
SMILES
C([C@H]1[C@H](C[C@@H](O)[C@@H]1/C=C/[C@@H](O)CCCCC)O)/C=C\CCCC(=O)O |&1:1,2,4,6,9,r|
CAS Datenbank
551-11-1(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Giftige Stoffe Daten 551-11-1(Hazardous Substances Data)
Toxizit?t LD50 in rabbits (mg/kg): 2.5-5.0 i.v.; 2.5-5.0 i.m. (Fujita)
Bildanzeige (GHS) GHS hazard pictogramsGHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
Sicherheit
P201 Vor Gebrauch besondere Anweisungen einholen.
P202 Vor Gebrauch alle Sicherheitshinweise lesen und verstehen.
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P301+P312 BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P308+P313 BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.

Prostaglandin F2a Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Prostaglandin F2α (PGF2α) is present in numerous species and has a widespread distribution. It can cause smooth muscle contraction in the vascular, bronchial, intestinal, and myometrial regions, and has potent luteolytic activity. PGF2α exerts its physiological effects through receptor mediation, with maximal ovine myometrial contraction being achieved at 125 nM PGF2α in vitro, and its receptor-mediated activity is most potent at 50-100 nM. Studies have also shown that PGF2α inhibits nitric oxide production in uterine tissue, enhances uterine contractility, and exhibits potent luteolytic activity. Furthermore, PGF2α functions as an activator of PGF2αR.

History

Prostaglandins (PGs) are a class of important endogenous products with a wide range of physiological activities. PGs were first discovered and named by American scholar Von Eluer in 1930. In 1962, Bergstorm extracted two pure PGs (PGF1 and PGF2) and determined their chemical structures. In 1969, Willis first proposed that PGs are an inflammatory mediator in the body. Subsequently, various physiological and pharmacological activities of PGs have been intensively studied.

Verwenden

Prostaglandin F2α is one of the most biologically studied of the primary prostaglandins. Closely related to Prostaglandin E2 (PGE2) in that both prostaglandins are biosynthesized from the same precursors and that PGF2 is the synthetic reduction product of PGE2.

Definition

ChEBI: Prostaglandin F2α is a prostaglandins Falpha that is prosta-5,13-dien-1-oic acid substituted by hydroxy groups at positions 9, 11 and 15. It is a naturally occurring prostaglandin used to induce labor.

Pharmakokinetik

Dinoprost is a natural prostaglandin F2α (PGF2α), which can directly act on the myometrium, stimulate the pregnant uterus to contract the uterine muscle, and can soften and dilate the cervix, so it can be used for induced abortion and late labor induction. However, due to the instability of dinoprost at room temperature, inconvenient storage and transportation, complex synthesis process and high cost, the application of dinoprost is difficult to popularize.

Sicherheitsprofil

Poison by subcutaneous, intravenous, and intramuscular routes. Moderately toxic by ingestion. Human and experimental teratogenic and experimental reproductive effects. Human reproductive effects by subcutaneous, intravenous, intramuscular, intraperitoneal, intravaginal, and intraplacental routes: postpartum depression and other maternal effects, abortion, and changes in measures of ferulity. Human teratogenic effects by intraplacental route: extra embryonic structures. Human systemic effects by intravenous route: hypermoulity, diarrhea, nausea or vomiting. Human mutation data reported. When heated to decomposition it emits acrid smoke and fumes

Mode of action

Prostaglandin F2α (PGF2α) stimulates myometrial activity, relaxes the cervix, inhibits corpus luteal steroidogenesis, and induces luteolysis by direct action on the corpus luteum. In pregnancy, PGF2α is medically used to sustain contracture and provoke myometrial ischemia to accelerate labor and prevent significant blood loss in labor.

Prostaglandin F2a Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Prostaglandin F2a Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 179)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Sinoway Industrial co., ltd.
0592-5800732; +8613806035118
xie@china-sinoway.com China 988 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21634 55
Biochempartner
0086-13720134139
candy@biochempartner.com CHINA 965 58
Hubei xin bonus chemical co. LTD
86-13657291602
linda@hubeijusheng.com CHINA 22963 58
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19553 58
career henan chemical co
+86-0371-86658258 +8613203830695
factory@coreychem.com China 29811 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763
sales@tnjchem.com China 34563 58
Shanxi Xuanran Import and Export Trade Co., Ltd.
+8617735180244
mike_yan@xuanranglobal.com CHINA 4017 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167
1026@dideu.com China 7724 58

551-11-1()Verwandte Suche:


  • 9ALPHA,11ALPHA,15S-TRIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID
  • cyclosin
  • dinolytic
  • enzaprost
  • enzaprostf
  • glandin
  • l-pgf2-alpha
  • l-prostaglandinf2-alpha
  • panacelan
  • prosta-5,13-dien-1-oicacid,9,11,15-trihydroxy-,(5z,9-alpha,11-alpha,13e,15s)
  • prostaglandinf2a
  • prostalmonf
  • prostarmonf
  • prostinf2alpha
  • prostinf2-alpha
  • u-14583
  • Dinprost
  • 7-[(1R,2S,3R,5R)-3,5-dihydroxy-2-[(3S)-3-hydroxyoct-1-enyl]cyclopentyl]hept-5-enoic acid
  • 9α,11α,15(S)-Trihydroxy-5-cis-13-trans-prostadienoic acid
  • 9α,11α-PGF2
  • 9α,11α-PGF2α
  • Cyclosin (pharmaceutical)
  • Glandin N
  • Protamodin
  • (5Z,9a,11a,13E,15S)-9,11,15-Trihydroxyprosta-5,13-diene-1-oic acid
  • DINOPROST
  • (5z,9alpha,11alpha,13e,15s)-9,11,15-trihydroxyprosta-3,13-dien-1-oicacid
  • 2beta(s*,e),3alpha,5alpha))-alpha(z
  • (Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((S,E)-3-hydroxyoct-1-enyl)cyclopentyl)hept-5-enoic acid
  • (5Z,13E,15S)-9α,11β,15-Trihydroxyprosta-5,13-dien-1-oic acid
  • (5Z,9S,11S,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic acid
  • 11-epi-PGF2α
  • 11-epiprostaglandin F2α
  • Prostaglandin F2a/Dinoprost
  • Prostaglandin F2α Lipid Maps MS Standard
  • Dinoprost TroMetaMol(Prostaglandin F2a)
  • (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl)cyclopentyl)hept-5-enoic acid
  • (5Z,13E)-(15S)-9,11,15-trihydroxyprosta-5,13-dienoate
  • (5z,13e)-(15s)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate
  • 5Z13E-15S-9-ALPHA11-ALPHA15-TRIHY
  • 7-[3, 5-dihydroxy-2-(3-hydroxyl-1-octenyl) cyclopentyl]-5-heptenoic acid
  • Dinaprost
  • Dinoprost (Prostaglandin F2a)
  • 5-dihydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl)-7-(l-5-heptenoicaci
  • 7-(3,5-dihydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl)-5-heptenoicaci
  • 7-(3,5-dihydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl)-5-heptenoicaci(1r-(1
  • 7-(3,5-dihydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl)-5-heptenoicacid
  • 7-[3,5-dihydroxy-2(3-hydroxy-1-octenyl)cyclopentyl]-5-heptenoicacid
  • 9,11,15-trihydroxy-,(5z,9alpha,11alpha,13e,15s)-prosta-13-dien-1-oicacid
  • 9,11,15-trihydroxyprosta-5,13-dien-1-oicacid
  • amoglandin
  • PROSTAGLANDIN F2ALPHA
  • PGF2ALPHA
  • 4-(3-hydroxyoct-1-enyl)-5-methylcyclopentane-1,3-diol
  • PROSTAGLANDIN F2A; PGF2Α
  • ProstaglandinF2α>
  • Prostaglandin F2α
  • Prostaglandin F2α MaxSpec? Standard
Copyright 2019 ? ChemicalBook. All rights reserved